Matches in SemOpenAlex for { <https://semopenalex.org/work/W2999359160> ?p ?o ?g. }
- W2999359160 endingPage "110626" @default.
- W2999359160 startingPage "110626" @default.
- W2999359160 abstract "Abstract Developing a biomimetic substrate with intrinsic potential for cell attachment and growth has always been a tissue engineering challenge. In the present research, we successfully fabricated PMS:PLA nanofibrous scaffolds for the first time using electrospinning process by adjusting blending ratios, feed rates and polymer concentrations. A desirable composition was found when homogenous nanofibers with an average fiber diameter of 235 ± 38 nm were achieved at 10% w/v for PMS:PLA 60:40. The scaffolds were then characterized for their microstructure, mechanical strength and elasticity, degradation rate, porosity, wettability and cell/tissue compatibility. Mechanical analysis and degradation behavior of PMS:PLA nanofibrous scaffolds revealed appropriate elasticity, stiffness and strength, as well as degradation rate appropriate for soft tissues. Nitrogen adsorption-desorption analysis discovered that mesoporous nanofibers with enhanced specific surface area were fabricated. Further in vitro and in vivo biocompatibility evaluations revealed enhanced cytocompatibility, proliferation and tissue responses of PMS:PLA nanofibrous scaffolds with desirable cell-scaffold interactions. Moreover, PMS:PLA nanofibrous scaffolds exhibited negligible inflammatory responses with significantly thinner fibrotic capsule formation and minor infiltration of inflammatory cells compared to PLA nanofibers. These findings suggest that PMS/PLA nanofibrous scaffolds could be introduced as potential candidates with improved properties for soft tissue engineering applications." @default.
- W2999359160 created "2020-01-23" @default.
- W2999359160 creator A5006656522 @default.
- W2999359160 creator A5026781154 @default.
- W2999359160 creator A5029816593 @default.
- W2999359160 creator A5030964037 @default.
- W2999359160 creator A5035297545 @default.
- W2999359160 creator A5045740477 @default.
- W2999359160 creator A5064105810 @default.
- W2999359160 date "2020-05-01" @default.
- W2999359160 modified "2023-10-02" @default.
- W2999359160 title "Development of poly (mannitol sebacate)/poly (lactic acid) nanofibrous scaffolds with potential applications in tissue engineering" @default.
- W2999359160 cites W1884979014 @default.
- W2999359160 cites W1931979683 @default.
- W2999359160 cites W1939652426 @default.
- W2999359160 cites W1978063675 @default.
- W2999359160 cites W1983947541 @default.
- W2999359160 cites W1991366502 @default.
- W2999359160 cites W1991915912 @default.
- W2999359160 cites W1994054444 @default.
- W2999359160 cites W1998213702 @default.
- W2999359160 cites W1998568198 @default.
- W2999359160 cites W1998732209 @default.
- W2999359160 cites W2000537455 @default.
- W2999359160 cites W2002036385 @default.
- W2999359160 cites W2002783172 @default.
- W2999359160 cites W2005799832 @default.
- W2999359160 cites W2008805549 @default.
- W2999359160 cites W2025832438 @default.
- W2999359160 cites W2028746500 @default.
- W2999359160 cites W2029960863 @default.
- W2999359160 cites W2030358543 @default.
- W2999359160 cites W2039503495 @default.
- W2999359160 cites W2040824641 @default.
- W2999359160 cites W2046007813 @default.
- W2999359160 cites W2047404361 @default.
- W2999359160 cites W2048378992 @default.
- W2999359160 cites W2053750386 @default.
- W2999359160 cites W2056197223 @default.
- W2999359160 cites W2059987495 @default.
- W2999359160 cites W2064698848 @default.
- W2999359160 cites W2066496156 @default.
- W2999359160 cites W2068739980 @default.
- W2999359160 cites W2072212515 @default.
- W2999359160 cites W2087515198 @default.
- W2999359160 cites W2095296362 @default.
- W2999359160 cites W2099851825 @default.
- W2999359160 cites W2100169867 @default.
- W2999359160 cites W2135645930 @default.
- W2999359160 cites W2148328620 @default.
- W2999359160 cites W2162805862 @default.
- W2999359160 cites W2166204670 @default.
- W2999359160 cites W2170159489 @default.
- W2999359160 cites W2170486528 @default.
- W2999359160 cites W2170630327 @default.
- W2999359160 cites W2178403318 @default.
- W2999359160 cites W2192181205 @default.
- W2999359160 cites W2317604405 @default.
- W2999359160 cites W2330450111 @default.
- W2999359160 cites W2333953251 @default.
- W2999359160 cites W2400030127 @default.
- W2999359160 cites W2472156521 @default.
- W2999359160 cites W2511570442 @default.
- W2999359160 cites W2607497738 @default.
- W2999359160 cites W2620275281 @default.
- W2999359160 cites W2676409082 @default.
- W2999359160 cites W2784876442 @default.
- W2999359160 cites W2785642358 @default.
- W2999359160 cites W2896004505 @default.
- W2999359160 cites W2899635059 @default.
- W2999359160 cites W2946449467 @default.
- W2999359160 doi "https://doi.org/10.1016/j.msec.2020.110626" @default.
- W2999359160 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32204067" @default.
- W2999359160 hasPublicationYear "2020" @default.
- W2999359160 type Work @default.
- W2999359160 sameAs 2999359160 @default.
- W2999359160 citedByCount "22" @default.
- W2999359160 countsByYear W29993591602020 @default.
- W2999359160 countsByYear W29993591602021 @default.
- W2999359160 countsByYear W29993591602022 @default.
- W2999359160 countsByYear W29993591602023 @default.
- W2999359160 crossrefType "journal-article" @default.
- W2999359160 hasAuthorship W2999359160A5006656522 @default.
- W2999359160 hasAuthorship W2999359160A5026781154 @default.
- W2999359160 hasAuthorship W2999359160A5029816593 @default.
- W2999359160 hasAuthorship W2999359160A5030964037 @default.
- W2999359160 hasAuthorship W2999359160A5035297545 @default.
- W2999359160 hasAuthorship W2999359160A5045740477 @default.
- W2999359160 hasAuthorship W2999359160A5064105810 @default.
- W2999359160 hasConcept C126348684 @default.
- W2999359160 hasConcept C127413603 @default.
- W2999359160 hasConcept C136229726 @default.
- W2999359160 hasConcept C171250308 @default.
- W2999359160 hasConcept C185592680 @default.
- W2999359160 hasConcept C188027245 @default.
- W2999359160 hasConcept C192562407 @default.
- W2999359160 hasConcept C2775920511 @default.
- W2999359160 hasConcept C2778445172 @default.