Matches in SemOpenAlex for { <https://semopenalex.org/work/W2999384710> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W2999384710 endingPage "114" @default.
- W2999384710 startingPage "114" @default.
- W2999384710 abstract "Globally, cattle production has more than doubled since the 1960s, with widespread use of artificial insemination (AI) and an emphasis on a small pool of high genetic merit animals. Selecting AI bulls with optimal fertility is, therefore, vital, as impaired fertility reduces genetic gains and production, resulting in heavy financial and environmental losses. Chromosome translocations, particularly the 1;29 Robertsonian translocation, are a common cause of reduced fertility; however, reciprocal translocations are significantly underreported due to the difficulties inherent in analysing cattle chromosomes. Based on our porcine work, we have developed an approach for the unambiguous detection of Robertsonian and reciprocal translocations, using a multiple-hybridization probe detection strategy. We applied this method on the chromosomes of 39 bulls, detecting heterozygous and homozygous 1;29 translocations and a 12;23 reciprocal translocation in a total of seven animals. Previously, karyotype analysis was the only method of diagnosing chromosomal rearrangements in cattle, and was time-consuming and error-prone. With calving rates of only 50–60%, it is vital to reduce further fertility loss in order to maximise productivity. The approach developed here identifies abnormalities that DNA sequencing will not, and has the potential to lead to long-term gains, delivering meat and milk products in a more cost-effective and environmentally-responsible manner to a growing population." @default.
- W2999384710 created "2020-01-23" @default.
- W2999384710 creator A5044630886 @default.
- W2999384710 creator A5053044998 @default.
- W2999384710 creator A5082358610 @default.
- W2999384710 date "2020-01-10" @default.
- W2999384710 modified "2023-10-17" @default.
- W2999384710 title "A New Approach for Accurate Detection of Chromosome Rearrangements That Affect Fertility in Cattle" @default.
- W2999384710 cites W1591714523 @default.
- W2999384710 cites W1769878457 @default.
- W2999384710 cites W1995734829 @default.
- W2999384710 cites W1996371820 @default.
- W2999384710 cites W2007301866 @default.
- W2999384710 cites W2012719267 @default.
- W2999384710 cites W2017474322 @default.
- W2999384710 cites W2027096956 @default.
- W2999384710 cites W2074906381 @default.
- W2999384710 cites W2125534265 @default.
- W2999384710 cites W2613339742 @default.
- W2999384710 cites W2796438017 @default.
- W2999384710 cites W2901865939 @default.
- W2999384710 doi "https://doi.org/10.3390/ani10010114" @default.
- W2999384710 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7023336" @default.
- W2999384710 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31936776" @default.
- W2999384710 hasPublicationYear "2020" @default.
- W2999384710 type Work @default.
- W2999384710 sameAs 2999384710 @default.
- W2999384710 citedByCount "10" @default.
- W2999384710 countsByYear W29993847102021 @default.
- W2999384710 countsByYear W29993847102022 @default.
- W2999384710 countsByYear W29993847102023 @default.
- W2999384710 crossrefType "journal-article" @default.
- W2999384710 hasAuthorship W2999384710A5044630886 @default.
- W2999384710 hasAuthorship W2999384710A5053044998 @default.
- W2999384710 hasAuthorship W2999384710A5082358610 @default.
- W2999384710 hasBestOaLocation W29993847101 @default.
- W2999384710 hasConcept C104317684 @default.
- W2999384710 hasConcept C138626823 @default.
- W2999384710 hasConcept C150903083 @default.
- W2999384710 hasConcept C2778610407 @default.
- W2999384710 hasConcept C2779234561 @default.
- W2999384710 hasConcept C2780458022 @default.
- W2999384710 hasConcept C2908647359 @default.
- W2999384710 hasConcept C30481170 @default.
- W2999384710 hasConcept C518429986 @default.
- W2999384710 hasConcept C53226629 @default.
- W2999384710 hasConcept C54355233 @default.
- W2999384710 hasConcept C71924100 @default.
- W2999384710 hasConcept C86803240 @default.
- W2999384710 hasConcept C99454951 @default.
- W2999384710 hasConceptScore W2999384710C104317684 @default.
- W2999384710 hasConceptScore W2999384710C138626823 @default.
- W2999384710 hasConceptScore W2999384710C150903083 @default.
- W2999384710 hasConceptScore W2999384710C2778610407 @default.
- W2999384710 hasConceptScore W2999384710C2779234561 @default.
- W2999384710 hasConceptScore W2999384710C2780458022 @default.
- W2999384710 hasConceptScore W2999384710C2908647359 @default.
- W2999384710 hasConceptScore W2999384710C30481170 @default.
- W2999384710 hasConceptScore W2999384710C518429986 @default.
- W2999384710 hasConceptScore W2999384710C53226629 @default.
- W2999384710 hasConceptScore W2999384710C54355233 @default.
- W2999384710 hasConceptScore W2999384710C71924100 @default.
- W2999384710 hasConceptScore W2999384710C86803240 @default.
- W2999384710 hasConceptScore W2999384710C99454951 @default.
- W2999384710 hasIssue "1" @default.
- W2999384710 hasLocation W29993847101 @default.
- W2999384710 hasLocation W29993847102 @default.
- W2999384710 hasLocation W29993847103 @default.
- W2999384710 hasLocation W29993847104 @default.
- W2999384710 hasLocation W29993847105 @default.
- W2999384710 hasOpenAccess W2999384710 @default.
- W2999384710 hasPrimaryLocation W29993847101 @default.
- W2999384710 hasRelatedWork W1974626988 @default.
- W2999384710 hasRelatedWork W1994067797 @default.
- W2999384710 hasRelatedWork W2049456474 @default.
- W2999384710 hasRelatedWork W2059806707 @default.
- W2999384710 hasRelatedWork W2065394919 @default.
- W2999384710 hasRelatedWork W2093979098 @default.
- W2999384710 hasRelatedWork W2316471765 @default.
- W2999384710 hasRelatedWork W2359047259 @default.
- W2999384710 hasRelatedWork W2372905734 @default.
- W2999384710 hasRelatedWork W3007735571 @default.
- W2999384710 hasVolume "10" @default.
- W2999384710 isParatext "false" @default.
- W2999384710 isRetracted "false" @default.
- W2999384710 magId "2999384710" @default.
- W2999384710 workType "article" @default.