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- W2999406721 abstract "PURPOSE - Breast cancer-related lymphedema is a common and debilitating side effect of cancer treatment. This randomized trial compared the effect of progressive resistance- or aerobic-based exercise on breast cancer-related lymphedema extent and severity, as well as participants' muscular strength and endurance, aerobic fitness, body composition, upper-body function and quality of life. METHODS - Women with a clinical diagnosis of stable unilateral, upper-limb lymphedema secondary to breast cancer were randomly allocated to a resistance- (n=21) or aerobic-based (n=20) exercise group (12-week intervention). Women were assessed pre-, post- and 12 weeks post-intervention, with generalised estimating equation models used to compare over time changes in each group's lymphedema (two-tailed p<0.05). RESULTS - Lymphedema remained stable in both groups (as measured by bioimpedance spectroscopy and circumferences), with no significant differences between groups noted in lymphedema status. There was a significant (p<0.01) time by group effect for upper-body strength (assessed using 4-6 repetition maximum bench press), with the resistance-based exercise group increasing strength by 4.2 kg (3.2, 5.2) post-intervention compared to 1.2 kg (-0.1, 2.5) in the aerobic-based exercise group. Although not supported statistically, the aerobic-based exercise group reported a clinically relevant decline in number of symptoms post-intervention (-1.5 [-2.6, -0.3]), and women in both exercise groups experienced clinically meaningful improvements in lower-body endurance, aerobic fitness and quality of life by 12-week follow-up. DISCUSSION - Participating in resistance- or aerobic-based exercise did not change lymphedema status, but led to clinically relevant improvements in function and quality of life, with findings suggesting that neither mode is superior with respect to lymphoedema impact. As such, personal preferences, survivorship concerns and functional needs are important and relevant considerations when prescribing exercise mode to those with secondary lymphedema." @default.
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- W2999406721 date "2016-01-01" @default.
- W2999406721 modified "2023-09-24" @default.
- W2999406721 title "A randomized trial on the effect of exercise mode on breast cancer-related lymphedema" @default.
- W2999406721 hasPublicationYear "2016" @default.
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