FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2999441628> ?p ?o ?g. }

• W2999441628 endingPage "403" @default.
• W2999441628 startingPage "395" @default.
• W2999441628 abstract "To investigate whether exosomes derived from human umbilical cord mesenchymal stem cells (hucMSC-derived exosomes) can repair injured endometrial epithelial cells (EECs). HucMSC-derived exosomes and mouse primary EECs were isolated and purified. EECs were exposed to oxygen and glucose deprivation for 2 h followed by reoxygenation to mimic injury. After oxygen and glucose deprivation/reoxygenation (OGD/R), hucMSC-derived exosomes were added to the EEC culture medium. After 24 h of co-treatment, cell viability and cell death were tested by 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium assay and lactate dehydrogenase (LDH) assay, respectively. The expression of proinflammatory cytokines was tested by real-time PCR, enzyme-linked immunosorbent assay (ELISA), and Western blot to investigate the potential mechanism. Compared with the control group, 5, 10, and 15 μg/mL of hucMSC-derived exosomes significantly attenuated cell viability decrease and inhibited LDH release of injured EECs, but 1 μg/mL of hucMSC-derived exosomes had no effect on either cell viability or LDH release. Real-time PCR and ELISA analysis revealed that 10 μg/mL of hucMSC-derived exosomes significantly inhibited the release of interleukin-6 (IL-6) and interleukin-1 beta (IL-1β) and increased tumor necrosis factor alpha (TNFA) in injured EECs. In addition, 10 μg/mL of hucMSC-derived exosomes significantly inhibited toll-like receptor 4 (TLR4) and v-rel reticuloendotheliosis viral oncogene homolog A (RelA) expression in injured EECs. In OGD/R-induced injured EECs, hucMSC-derived exosomes efficiently improved the cell viability, reduced cell death, and exhibited anti-inflammatory properties against OGD/R." @default.
• W2999441628 created "2020-01-23" @default.
• W2999441628 creator A5003554962 @default.
• W2999441628 creator A5004638032 @default.
• W2999441628 creator A5023128001 @default.
• W2999441628 creator A5026762317 @default.
• W2999441628 creator A5040859980 @default.
• W2999441628 creator A5081209056 @default.
• W2999441628 creator A5082585878 @default.
• W2999441628 creator A5086134325 @default.
• W2999441628 date "2020-01-15" @default.
• W2999441628 modified "2023-10-12" @default.
• W2999441628 title "Exosomes derived from human umbilical cord mesenchymal stem cells repair injured endometrial epithelial cells" @default.
• W2999441628 cites W1488278893 @default.
• W2999441628 cites W1560695875 @default.
• W2999441628 cites W1839188703 @default.
• W2999441628 cites W1979493465 @default.
• W2999441628 cites W1983897480 @default.
• W2999441628 cites W1989796399 @default.
• W2999441628 cites W2011508825 @default.
• W2999441628 cites W2015985418 @default.
• W2999441628 cites W2055424631 @default.
• W2999441628 cites W2066426973 @default.
• W2999441628 cites W2067591094 @default.
• W2999441628 cites W2091168675 @default.
• W2999441628 cites W2097605647 @default.
• W2999441628 cites W2124925707 @default.
• W2999441628 cites W2127954353 @default.
• W2999441628 cites W2145142940 @default.
• W2999441628 cites W2146213972 @default.
• W2999441628 cites W2150395626 @default.
• W2999441628 cites W2264590390 @default.
• W2999441628 cites W2308714122 @default.
• W2999441628 cites W2342859699 @default.
• W2999441628 cites W2384442937 @default.
• W2999441628 cites W2521917870 @default.
• W2999441628 cites W2605484523 @default.
• W2999441628 cites W2619612702 @default.
• W2999441628 cites W2738491178 @default.
• W2999441628 cites W2768238755 @default.
• W2999441628 cites W2802550300 @default.
• W2999441628 cites W2840917343 @default.
• W2999441628 cites W2898620570 @default.
• W2999441628 cites W2913330914 @default.
• W2999441628 cites W2915270257 @default.
• W2999441628 cites W2937630149 @default.
• W2999441628 doi "https://doi.org/10.1007/s10815-019-01687-4" @default.
• W2999441628 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7056758" @default.
• W2999441628 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31938932" @default.
• W2999441628 hasPublicationYear "2020" @default.
• W2999441628 type Work @default.
• W2999441628 sameAs 2999441628 @default.
• W2999441628 citedByCount "9" @default.
• W2999441628 countsByYear W29994416282020 @default.
• W2999441628 countsByYear W29994416282021 @default.
• W2999441628 countsByYear W29994416282022 @default.
• W2999441628 countsByYear W29994416282023 @default.
• W2999441628 crossrefType "journal-article" @default.
• W2999441628 hasAuthorship W2999441628A5003554962 @default.
• W2999441628 hasAuthorship W2999441628A5004638032 @default.
• W2999441628 hasAuthorship W2999441628A5023128001 @default.
• W2999441628 hasAuthorship W2999441628A5026762317 @default.
• W2999441628 hasAuthorship W2999441628A5040859980 @default.
• W2999441628 hasAuthorship W2999441628A5081209056 @default.
• W2999441628 hasAuthorship W2999441628A5082585878 @default.
• W2999441628 hasAuthorship W2999441628A5086134325 @default.
• W2999441628 hasBestOaLocation W29994416282 @default.
• W2999441628 hasConcept C104317684 @default.
• W2999441628 hasConcept C145059251 @default.
• W2999441628 hasConcept C1491633281 @default.
• W2999441628 hasConcept C153911025 @default.
• W2999441628 hasConcept C164027704 @default.
• W2999441628 hasConcept C16685009 @default.
• W2999441628 hasConcept C181199279 @default.
• W2999441628 hasConcept C198826908 @default.
• W2999441628 hasConcept C203014093 @default.
• W2999441628 hasConcept C20518536 @default.
• W2999441628 hasConcept C2776914184 @default.
• W2999441628 hasConcept C2777318727 @default.
• W2999441628 hasConcept C2781261824 @default.
• W2999441628 hasConcept C53227056 @default.
• W2999441628 hasConcept C55493867 @default.
• W2999441628 hasConcept C71924100 @default.
• W2999441628 hasConcept C86803240 @default.
• W2999441628 hasConcept C95444343 @default.
• W2999441628 hasConceptScore W2999441628C104317684 @default.
• W2999441628 hasConceptScore W2999441628C145059251 @default.
• W2999441628 hasConceptScore W2999441628C1491633281 @default.
• W2999441628 hasConceptScore W2999441628C153911025 @default.
• W2999441628 hasConceptScore W2999441628C164027704 @default.
• W2999441628 hasConceptScore W2999441628C16685009 @default.
• W2999441628 hasConceptScore W2999441628C181199279 @default.
• W2999441628 hasConceptScore W2999441628C198826908 @default.
• W2999441628 hasConceptScore W2999441628C203014093 @default.
• W2999441628 hasConceptScore W2999441628C20518536 @default.
• W2999441628 hasConceptScore W2999441628C2776914184 @default.
• W2999441628 hasConceptScore W2999441628C2777318727 @default.
• W2999441628 hasConceptScore W2999441628C2781261824 @default.

• next