Matches in SemOpenAlex for { <https://semopenalex.org/work/W2999445652> ?p ?o ?g. }
Showing items 1 to 47 of
47
with 100 items per page.
- W2999445652 abstract "Abstract Background Efficient IBD symptomatic control, especially in severe patients, is still lacking while conventional management options agents carry risks for long-term side effects such as malignancy and infections. Only about 60% of IBD patients initially respond to conventional therapy thus, a growing number of IBD patients turn to use medical cannabis to relieve their symptoms. The large selection of cannabis varieties available in the markets, together with lack of evidence-based cannabis therapy guidelines, practically turns cannabis care to a self-medicating hit-or-miss treatment. Yet, despite its large therapeutic window, cannabis care still carries unknown risks of short-and long-term side effects and tolerance. SelfX is a novel cannabis-therapy management web platform, designed to monitor patients in various clinical conditions. It is a cloud-based decision-support physician tool, consisting of personal patient wearable monitoring device, mobile app and physician web portal. Methods SelfX capability to detect and alert of IBD patients in need of cannabis treatment protocol change consideration (including cessation of treatment), was examined in a proof of concept observational clinical study. Men and Women aged 18–65 (n = 26) with IBD who were already treated with cannabis prior to the study initiation, and held a valid cannabis license from the Israeli Ministry of Health, were recruited at Meir Medical Center in Israel and completed 6 weeks of remote monitoring. A designated statistical formula developed by our team for change-point detection was applied to alert of any negative clinical trends, including an increase in resting heart rate, decrease in sleep quality, increase in daily self-report IBD scoring system, adverse events and cannabis patterns use. Results The study achieved its primary objective to alert in real-time of detected change points which enabled an educated calibration of a personal adaptive alerts function. Study group post hoc analysis revealed significant and informative system performance: 60 objective negative trends alerts, and 27 subjective negative trends alerts were detected in real time. Conclusion Currently physicians require a practical tool to monitor short-and long-term safety and efficiency of cannabis use. Our work demonstrates the importance of continuous remote monitoring alongside laboratory routine measurements for IBD patients treated with cannabis. Future interventional studies will expand valuable monitored parameters scope range and will associate monitored data points with personal cannabis patterns use. SelfX platform offers a safety-net and an educated adaptive optimisation tool for continuous remote patients management in real time." @default.
- W2999445652 created "2020-01-23" @default.
- W2999445652 creator A5003675346 @default.
- W2999445652 creator A5031986705 @default.
- W2999445652 creator A5033531513 @default.
- W2999445652 date "2020-01-01" @default.
- W2999445652 modified "2023-09-23" @default.
- W2999445652 title "P504 Remote cannabis-therapy management platform for IBD patients: performance assessment" @default.
- W2999445652 doi "https://doi.org/10.1093/ecco-jcc/jjz203.633" @default.
- W2999445652 hasPublicationYear "2020" @default.
- W2999445652 type Work @default.
- W2999445652 sameAs 2999445652 @default.
- W2999445652 citedByCount "0" @default.
- W2999445652 crossrefType "journal-article" @default.
- W2999445652 hasAuthorship W2999445652A5003675346 @default.
- W2999445652 hasAuthorship W2999445652A5031986705 @default.
- W2999445652 hasAuthorship W2999445652A5033531513 @default.
- W2999445652 hasBestOaLocation W29994456521 @default.
- W2999445652 hasConcept C118552586 @default.
- W2999445652 hasConcept C126322002 @default.
- W2999445652 hasConcept C177713679 @default.
- W2999445652 hasConcept C23131810 @default.
- W2999445652 hasConcept C2777056318 @default.
- W2999445652 hasConcept C71924100 @default.
- W2999445652 hasConceptScore W2999445652C118552586 @default.
- W2999445652 hasConceptScore W2999445652C126322002 @default.
- W2999445652 hasConceptScore W2999445652C177713679 @default.
- W2999445652 hasConceptScore W2999445652C23131810 @default.
- W2999445652 hasConceptScore W2999445652C2777056318 @default.
- W2999445652 hasConceptScore W2999445652C71924100 @default.
- W2999445652 hasLocation W29994456521 @default.
- W2999445652 hasOpenAccess W2999445652 @default.
- W2999445652 hasPrimaryLocation W29994456521 @default.
- W2999445652 hasRelatedWork W14033268 @default.
- W2999445652 hasRelatedWork W14433664 @default.
- W2999445652 hasRelatedWork W15158175 @default.
- W2999445652 hasRelatedWork W17121398 @default.
- W2999445652 hasRelatedWork W17966948 @default.
- W2999445652 hasRelatedWork W1895107 @default.
- W2999445652 hasRelatedWork W20363096 @default.
- W2999445652 hasRelatedWork W2372034 @default.
- W2999445652 hasRelatedWork W4820804 @default.
- W2999445652 hasRelatedWork W19225616 @default.
- W2999445652 isParatext "false" @default.
- W2999445652 isRetracted "false" @default.
- W2999445652 magId "2999445652" @default.
- W2999445652 workType "article" @default.