Matches in SemOpenAlex for { <https://semopenalex.org/work/W2999462843> ?p ?o ?g. }
Showing items 1 to 71 of
71
with 100 items per page.
- W2999462843 abstract "ACINETOBACTER baumannii (A. baumannii ) is considered one of the predominant antibiotic resistance pathogens involved in hospital acquired infections worldwide problem. The study investigated the effect of antibiotic combination of β-lactams (ceftriaxone, cefixime, carpabenem and impenim) and aminoglycosides against 5 clinical isolates of A. baumannii multidrug resistant. Over one year, 250 bacterial isolates were collected from 5 Egyptian hospitals from various infection sites. Two hundred out of 250 bacterial isolates were identified as A. baumannii based on phenotypic and genotypic techniques. The susceptibility of two-hundred A. baumannii strains against 21 different antibiotics was studied. The results showed that the highest resistance was to Cephalosporins, group was 99% followed by Quinolones & Fluoroquinolone was 90, 5 followed by penicillin 87.5, then Sulfa drugs was 75.5 then Carbapenem was 73 and finally Aminoglycosides was 60.5%. The minimum inhibitory concentration (MICs) values of aminoglycosides resistant A. baumannii strains ranged from 32 to >512mg/ml and β-lactam group ranged from 16 to >512mg/ml. Forty-five combined microtitre checkerboards were performed against the 5 totally aminoglycoside resistant A. baumannii strains to assess the potential for combination therapy. Combination of aminoglycoside antibiotics with β-lactams showed synergy action in thirty- eight (84%) of total forty-five combinations. Synergy was achieved with 100%, with the following combinations GN/IMP, GN/CRO, GN/CFM, AK/CRO, AK/CFM, TOB/CRO and TOB/CFM. No synergism was observed with combination between amikacin and imipenem." @default.
- W2999462843 created "2020-01-23" @default.
- W2999462843 creator A5024135376 @default.
- W2999462843 creator A5024726141 @default.
- W2999462843 creator A5067934800 @default.
- W2999462843 creator A5074371113 @default.
- W2999462843 date "2020-01-02" @default.
- W2999462843 modified "2023-10-15" @default.
- W2999462843 title "Susceptibility of Aminoglycoside Resistant Acinetobacter baumannii to Antibiotic Combinations" @default.
- W2999462843 doi "https://doi.org/10.21608/ejm.2019.16809.1115" @default.
- W2999462843 hasPublicationYear "2020" @default.
- W2999462843 type Work @default.
- W2999462843 sameAs 2999462843 @default.
- W2999462843 citedByCount "0" @default.
- W2999462843 crossrefType "journal-article" @default.
- W2999462843 hasAuthorship W2999462843A5024135376 @default.
- W2999462843 hasAuthorship W2999462843A5024726141 @default.
- W2999462843 hasAuthorship W2999462843A5067934800 @default.
- W2999462843 hasAuthorship W2999462843A5074371113 @default.
- W2999462843 hasBestOaLocation W29994628431 @default.
- W2999462843 hasConcept C174802600 @default.
- W2999462843 hasConcept C2776315533 @default.
- W2999462843 hasConcept C2776685102 @default.
- W2999462843 hasConcept C2777427914 @default.
- W2999462843 hasConcept C2777637488 @default.
- W2999462843 hasConcept C2777787772 @default.
- W2999462843 hasConcept C2778243283 @default.
- W2999462843 hasConcept C2778523567 @default.
- W2999462843 hasConcept C2779631663 @default.
- W2999462843 hasConcept C501593827 @default.
- W2999462843 hasConcept C523546767 @default.
- W2999462843 hasConcept C54355233 @default.
- W2999462843 hasConcept C64778159 @default.
- W2999462843 hasConcept C71924100 @default.
- W2999462843 hasConcept C86803240 @default.
- W2999462843 hasConcept C89423630 @default.
- W2999462843 hasConcept C94665300 @default.
- W2999462843 hasConceptScore W2999462843C174802600 @default.
- W2999462843 hasConceptScore W2999462843C2776315533 @default.
- W2999462843 hasConceptScore W2999462843C2776685102 @default.
- W2999462843 hasConceptScore W2999462843C2777427914 @default.
- W2999462843 hasConceptScore W2999462843C2777637488 @default.
- W2999462843 hasConceptScore W2999462843C2777787772 @default.
- W2999462843 hasConceptScore W2999462843C2778243283 @default.
- W2999462843 hasConceptScore W2999462843C2778523567 @default.
- W2999462843 hasConceptScore W2999462843C2779631663 @default.
- W2999462843 hasConceptScore W2999462843C501593827 @default.
- W2999462843 hasConceptScore W2999462843C523546767 @default.
- W2999462843 hasConceptScore W2999462843C54355233 @default.
- W2999462843 hasConceptScore W2999462843C64778159 @default.
- W2999462843 hasConceptScore W2999462843C71924100 @default.
- W2999462843 hasConceptScore W2999462843C86803240 @default.
- W2999462843 hasConceptScore W2999462843C89423630 @default.
- W2999462843 hasConceptScore W2999462843C94665300 @default.
- W2999462843 hasLocation W29994628431 @default.
- W2999462843 hasOpenAccess W2999462843 @default.
- W2999462843 hasPrimaryLocation W29994628431 @default.
- W2999462843 hasRelatedWork W10573300 @default.
- W2999462843 hasRelatedWork W10943807 @default.
- W2999462843 hasRelatedWork W14370425 @default.
- W2999462843 hasRelatedWork W2818026 @default.
- W2999462843 hasRelatedWork W3861333 @default.
- W2999462843 hasRelatedWork W3890731 @default.
- W2999462843 hasRelatedWork W4498081 @default.
- W2999462843 hasRelatedWork W5665659 @default.
- W2999462843 hasRelatedWork W9540093 @default.
- W2999462843 hasRelatedWork W9064380 @default.
- W2999462843 isParatext "false" @default.
- W2999462843 isRetracted "false" @default.
- W2999462843 magId "2999462843" @default.
- W2999462843 workType "article" @default.