FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2999503540> ?p ?o ?g. }

• W2999503540 endingPage "594" @default.
• W2999503540 startingPage "588" @default.
• W2999503540 abstract "Abstract Background and Aims The relationship between inflammatory bowel disease in pregnancy and birth defects is not understood. We evaluated whether Crohn’s disease and ulcerative colitis in pregnant women were associated with the risk of birth defects in the offspring. Methods We undertook a retrospective cohort study of 2 184 888 pregnancies in Quebec, Canada, between 1989 and 2016. We calculated risk ratios [RR] and 95% confidence intervals [CI] for the association between inflammatory bowel disease and the risk of birth defects, using generalised estimating equations adjusted for maternal characteristics. We assessed associations in the period before 2000, when immunosuppressive biologic therapy and folic acid food fortification were not yet available, compared with the period after 2000 when these interventions were more widespread. Results This study included 13 099 women with Crohn’s disease and 7798 with ulcerative colitis. Crohn’s disease was associated with 1.90 times [95% CI 1.10–3.28] the risk of abdominal wall defects [gastroschisis, omphalocoele, and diaphragmatic hernia] and ulcerative colitis was associated with 1.53 times [95% CI 1.02–2.30] the risk of central nervous system defects. The association of Crohn’s disease with abdominal wall defects was stronger before 2000 [RR 3.62, 95% CI 1.71–7.67] than after 2000 [RR 1.23, 95% CI 0.55–2.75]. Ulcerative colitis was associated with central nervous system defects regardless of time period. Conclusions These findings suggest that inflammatory bowel disease is associated with the risk of abdominal wall and central nervous system defects, and that introduction of immunobiologic medications is unlikely to be associated with added risk. Podcast This article has an associated podcast which can be accessed at https://academic.oup.com/ecco-jcc/pages/podcast" @default.
• W2999503540 created "2020-01-23" @default.
• W2999503540 creator A5005579212 @default.
• W2999503540 creator A5057924790 @default.
• W2999503540 creator A5062902281 @default.
• W2999503540 creator A5084689710 @default.
• W2999503540 date "2020-01-07" @default.
• W2999503540 modified "2023-10-14" @default.
• W2999503540 title "Inflammatory Bowel Disease and Risk of Birth Defects in Offspring" @default.
• W2999503540 cites W1547943993 @default.
• W2999503540 cites W1992819061 @default.
• W2999503540 cites W199967711 @default.
• W2999503540 cites W2006782464 @default.
• W2999503540 cites W2033315477 @default.
• W2999503540 cites W2034217591 @default.
• W2999503540 cites W2045915839 @default.
• W2999503540 cites W2046673451 @default.
• W2999503540 cites W2080814854 @default.
• W2999503540 cites W2100626976 @default.
• W2999503540 cites W2116676647 @default.
• W2999503540 cites W2127935571 @default.
• W2999503540 cites W2146636273 @default.
• W2999503540 cites W2149860264 @default.
• W2999503540 cites W2160101621 @default.
• W2999503540 cites W2185850265 @default.
• W2999503540 cites W2189150428 @default.
• W2999503540 cites W2335213225 @default.
• W2999503540 cites W2532905842 @default.
• W2999503540 cites W2587944265 @default.
• W2999503540 cites W2597714858 @default.
• W2999503540 cites W2741205354 @default.
• W2999503540 cites W2763369925 @default.
• W2999503540 cites W2971406729 @default.
• W2999503540 cites W4210972027 @default.
• W2999503540 cites W4294959435 @default.
• W2999503540 cites W591438761 @default.
• W2999503540 doi "https://doi.org/10.1093/ecco-jcc/jjz211" @default.
• W2999503540 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31907519" @default.
• W2999503540 hasPublicationYear "2020" @default.
• W2999503540 type Work @default.
• W2999503540 sameAs 2999503540 @default.
• W2999503540 citedByCount "4" @default.
• W2999503540 countsByYear W29995035402020 @default.
• W2999503540 countsByYear W29995035402021 @default.
• W2999503540 countsByYear W29995035402022 @default.
• W2999503540 crossrefType "journal-article" @default.
• W2999503540 hasAuthorship W2999503540A5005579212 @default.
• W2999503540 hasAuthorship W2999503540A5057924790 @default.
• W2999503540 hasAuthorship W2999503540A5062902281 @default.
• W2999503540 hasAuthorship W2999503540A5084689710 @default.
• W2999503540 hasConcept C112672928 @default.
• W2999503540 hasConcept C126322002 @default.
• W2999503540 hasConcept C131872663 @default.
• W2999503540 hasConcept C167135981 @default.
• W2999503540 hasConcept C172680121 @default.
• W2999503540 hasConcept C201903717 @default.
• W2999503540 hasConcept C2777428835 @default.
• W2999503540 hasConcept C2778260677 @default.
• W2999503540 hasConcept C2779134260 @default.
• W2999503540 hasConcept C2779234561 @default.
• W2999503540 hasConcept C2779280984 @default.
• W2999503540 hasConcept C2780479503 @default.
• W2999503540 hasConcept C44249647 @default.
• W2999503540 hasConcept C54355233 @default.
• W2999503540 hasConcept C71924100 @default.
• W2999503540 hasConcept C82789193 @default.
• W2999503540 hasConcept C86803240 @default.
• W2999503540 hasConcept C90924648 @default.
• W2999503540 hasConceptScore W2999503540C112672928 @default.
• W2999503540 hasConceptScore W2999503540C126322002 @default.
• W2999503540 hasConceptScore W2999503540C131872663 @default.
• W2999503540 hasConceptScore W2999503540C167135981 @default.
• W2999503540 hasConceptScore W2999503540C172680121 @default.
• W2999503540 hasConceptScore W2999503540C201903717 @default.
• W2999503540 hasConceptScore W2999503540C2777428835 @default.
• W2999503540 hasConceptScore W2999503540C2778260677 @default.
• W2999503540 hasConceptScore W2999503540C2779134260 @default.
• W2999503540 hasConceptScore W2999503540C2779234561 @default.
• W2999503540 hasConceptScore W2999503540C2779280984 @default.
• W2999503540 hasConceptScore W2999503540C2780479503 @default.
• W2999503540 hasConceptScore W2999503540C44249647 @default.
• W2999503540 hasConceptScore W2999503540C54355233 @default.
• W2999503540 hasConceptScore W2999503540C71924100 @default.
• W2999503540 hasConceptScore W2999503540C82789193 @default.
• W2999503540 hasConceptScore W2999503540C86803240 @default.
• W2999503540 hasConceptScore W2999503540C90924648 @default.
• W2999503540 hasFunder F4320312568 @default.
• W2999503540 hasIssue "5" @default.
• W2999503540 hasLocation W29995035401 @default.
• W2999503540 hasOpenAccess W2999503540 @default.
• W2999503540 hasPrimaryLocation W29995035401 @default.
• W2999503540 hasRelatedWork W2044341494 @default.
• W2999503540 hasRelatedWork W2070285775 @default.
• W2999503540 hasRelatedWork W2124908533 @default.
• W2999503540 hasRelatedWork W2258300052 @default.
• W2999503540 hasRelatedWork W2408939568 @default.
• W2999503540 hasRelatedWork W2409879998 @default.
• W2999503540 hasRelatedWork W2412773332 @default.

• next