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- W2999587077 abstract "The Cunila angustifolia essential oil was obtained from fresh leaves by hydrodistillation and analyzed by GC-FID and GC-MS to determine its chemical composition. The essential oil presented pulegone (29.5 %) and isomenthol (27.0 %) as major components, and other compounds such as menthone (8.6 %), neomenthol (7.2 %), menthyl acetate (2.5 %) and caryophyllene oxide (2.0 %) were identified. The cytotoxic activity of the essential oil was evaluated by MTS assay, with the human cancer cell lines of the lung (A549), breast (MCF-7) and skin melanoma (SK-Mel-28). The assay showed the highest selectivity, to MCF-7 cell lines, with IC50 equal to 34.0 μg mL-1 , low selectivity for SK-Mel-28 cell lines, with IC50 equal to 279.9 μg mL-1 , and no mortality to A549 cell lines." @default.
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- W2999587077 date "2020-01-27" @default.
- W2999587077 modified "2023-09-30" @default.
- W2999587077 title "Cytotoxic Activity of <i>Cunila angustifolia</i> Essential Oil" @default.
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- W2999587077 doi "https://doi.org/10.1002/cbdv.201900656" @default.
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