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• W2999682341 abstract "Abstract The hemostatic properties of platelets in cattle are physiologically very significant, as they affect the course of metabolic processes. This is especially significant in early ontogenesis and, apparently, strongly depends on the genetic characteristics of animals. The study was carried out on 37 Dutch calves, which were obtained from healthy cows after a normal pregnancy. All calves were examined and examined for 1-2 days, 3-4 days, 5-6 days, 7-8 days and 9-10 days of their ontogenesis. In the work were applied biochemical, hematological and statistical research methods. In the examined animals, during the neonatal phase, there was a tendency to inhibition of platelet aggregation in response to all inductors used. The number of platelet-discocytes in the blood of the examined Dutch calves in the first 10 days of their life experienced an upward trend. The amount of active platelet species they had decreased by 11.1%. The number of small and large platelet aggregates in the blood also decreased in them during the observation period. This was provided in the observed calves with a tendency to weaken the severity of synthesis in thromboxane platelets, a decrease in the level of adenosine phosphates in them and a weakening of their secretion. The level of platelet actin and myosin on the 1-2nd day in the examined calves was small and tended to decrease during the observation. Additional self-assembly of actin and myosin during platelet aggregation of the observed animals experienced some decrease during the observation period. It is clear that newborn calves of the Dutch breed are characterized by a high degree of functional sufficiency of platelets, creating physiologically favorable conditions for microcirculation processes. At the basis of these changes they have a small activity of the mechanisms that implement the hemostatic properties of platelets. Low intravascular activity of platelets in newborn calves of the Dutch breed is able to provide them with optimum perfusion and metabolic processes in all animal tissues that are necessary for the normal development of animals." @default.
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• W2999682341 date "2020-01-01" @default.
• W2999682341 modified "2023-10-01" @default.
• W2999682341 title "Functional platelet activity in Dutch newborn calves" @default.
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• W2999682341 doi "https://doi.org/10.1088/1755-1315/421/2/022042" @default.
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