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- W2999687032 abstract "High blood glucose (HBG) at admission is a major common metabolic disorder in patients with acute myocardial infarction (MI). However, only few data have examined its predictive performance over established risk score. The aim of our study was to determine the correlation between hyperglycemia at admission in non-diabetic patients and the severity of coronary artery lesions evaluated by the Synthax score. We conducted a cross-sectional study including all the patients admitted for MI in the cardiology intensive care unit of Casablanca from june 2018 to february 2019. The population was divided into 2 groups: hyperglycemia (glycemia at admission > 1.10 g/l) and non-hyperglycemia (< 1.10 g/l) regardless of previous diabetic status. The primary composite endpoint (all-cause death and non-fatal MI) was compared between the two groups. A total of 193 patients were included. A total of 63.4% presented with hyperglycemia on admission, 89% were over 65 years. There were significant differences in baseline clinical status established by calculating CHADSVASC score (2.60 ± 1.54 vs 1.5 ± 1.05; P = 0.01). Biological status differed significantly between the 2 groups especially troponine Ic, LDL cholesterol and triglyceride which were higher in HBG patients (32.20 ± 63.93 vs. 17.64 ± 31.16 P = 0.014; 0.94 ± 0.33 vs. 0.87 ± 0,27 P = 0.015; 1.45 ± 0.67 vs. 1.16 ± 0.42 P = 0.04 respectively). SYNTAX score was higher in the hyperglycemia group 11.21 ± 8.377 vs. 7.50 ± 8.782 P = 0.03. A multivariate analysis showed that hyperglycemia on admission was an independent predictor of severity of coronary artery lesions and was significantly associated with long-term clinical outcomes. In non-diabetic patients with MI, hyperglycemia on admission was predictive of coronary artery lesions’ severity and was associated with poor long-term clinical outcomes. Further study is needed to evaluate specific therapeutic strategies to prevent cardiovascular events occurring in these patients." @default.
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- W2999687032 date "2020-01-01" @default.
- W2999687032 modified "2023-09-25" @default.
- W2999687032 title "Evaluation of hyperglycemia at admission as a marker of severity of coronary lesions in non-diabetic patients with myocardial infarction" @default.
- W2999687032 doi "https://doi.org/10.1016/j.acvdsp.2019.09.414" @default.
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