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- W2999692671 abstract "The recent development of monoclonal antibodies (mAbs) has revolutionized the treatment armamentarium for multiple myeloma. The success of daratumumab and elotuzumab in relapsed/refractory patients, has generated tremendous enthusiasm for mAbs in this disease. Combination treatment with other anti-myeloma treatment modalities and clinical evaluation in newly diagnosed patients are expected to fundamentally change the natural history of the disease. Advances in biopharmaceutical engineering together with a robust interest in novel mAb-derivatives, including antibody drug conjugates and poly-specific antibodies are the next rapidly approaching treatment frontier in multiple myeloma. In this review, we comprehensively outline the currently available evidence and the future landscape of mAbs and mAb-derivative therapies in multiple myeloma." @default.
- W2999692671 created "2020-01-23" @default.
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- W2999692671 date "2020-03-01" @default.
- W2999692671 modified "2023-10-14" @default.
- W2999692671 title "Monoclonal antibodies in multiple myeloma: Current and emerging targets and mechanisms of action" @default.
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- W2999692671 doi "https://doi.org/10.1016/j.beha.2020.101143" @default.
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