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- W2999978118 endingPage "253" @default.
- W2999978118 startingPage "253" @default.
- W2999978118 abstract "Ischemia and reperfusion injury (IRI) is a complex pathophysiological phenomenon, inevitable in kidney transplantation and one of the most important mechanisms for non- or delayed function immediately after transplantation. Long term, it is associated with acute rejection and chronic graft dysfunction due to interstitial fibrosis and tubular atrophy. Recently, more insight has been gained in the underlying molecular pathways and signalling cascades involved, which opens the door to new therapeutic opportunities aiming to reduce IRI and improve graft survival. This review systemically discusses the specific molecular pathways involved in the pathophysiology of IRI and highlights new therapeutic strategies targeting these pathways." @default.
- W2999978118 created "2020-01-23" @default.
- W2999978118 creator A5023696538 @default.
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- W2999978118 creator A5088588502 @default.
- W2999978118 date "2020-01-17" @default.
- W2999978118 modified "2023-10-11" @default.
- W2999978118 title "Ischemia and Reperfusion Injury in Kidney Transplantation: Relevant Mechanisms in Injury and Repair" @default.
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