FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3000000149> ?p ?o ?g. }

• W3000000149 endingPage "401" @default.
• W3000000149 startingPage "394" @default.
• W3000000149 abstract "Purpose: Children with Ewing sarcoma (ES) routinely undergo surveillance imaging after completion of therapy; however, the medical benefit of this imaging remains unclear. We aimed to determine whether there is a difference in survival between patients whose relapse was detected based on development of new symptoms or by routine imaging. Methods: We retrospectively reviewed all patients consecutively diagnosed with ES at Children's Healthcare of Atlanta from 2000 to 2011. Patient characteristics and outcomes were compared based on whether their relapse was diagnosed based on symptoms or by routine surveillance imaging alone. Results: Thirty-three percent (28/85) of patients relapsed. Median age at time of relapse was 15.5 years (interquartile range: 12.5–18.0). Among the relapsed patients, 57% (16/28) were symptomatic and 43% (12/28) were asymptomatic, having relapse detected on surveillance imaging alone. The most common presenting symptom was bone pain occurring in 69% (11/16) of patients. The 5-year postrelapse overall survival for patients with symptomatic relapse was 0% (95% confidence interval [CI]: not estimated) compared with 15% (95% CI: 1–48) for patients with an asymptomatic relapse (p < 0.01). After adjusting for extent of disease and time to relapse, having a symptomatic relapse was still strongly associated with a worse outcome (hazard ratio: 9.68; 95% CI: 3.09–30.34). Conclusion: Patients with ES whose relapse is detected on imaging before the development of symptoms have significantly better outcomes, suggesting a potentially beneficial role of routine surveillance imaging in this population of patients. Further prospective analyses are needed to confirm these findings, and determine the optimal evidence-based imaging modality and schedule." @default.
• W3000000149 created "2020-01-23" @default.
• W3000000149 creator A5010118231 @default.
• W3000000149 creator A5021513699 @default.
• W3000000149 creator A5022822432 @default.
• W3000000149 creator A5025991543 @default.
• W3000000149 creator A5026538997 @default.
• W3000000149 creator A5035520605 @default.
• W3000000149 creator A5041441527 @default.
• W3000000149 creator A5068808085 @default.
• W3000000149 creator A5076151504 @default.
• W3000000149 date "2020-06-01" @default.
• W3000000149 modified "2023-10-13" @default.
• W3000000149 title "Routine Surveillance Imaging Is Associated with Improved Postrelapse Survival in Patients with Ewing Sarcoma" @default.
• W3000000149 cites W1932539317 @default.
• W3000000149 cites W2034600493 @default.
• W3000000149 cites W2042936828 @default.
• W3000000149 cites W2050780415 @default.
• W3000000149 cites W2055819634 @default.
• W3000000149 cites W2060028233 @default.
• W3000000149 cites W2072909107 @default.
• W3000000149 cites W2073286211 @default.
• W3000000149 cites W2113093883 @default.
• W3000000149 cites W2128628566 @default.
• W3000000149 cites W2137571255 @default.
• W3000000149 cites W2145380561 @default.
• W3000000149 cites W2168955110 @default.
• W3000000149 cites W2792688806 @default.
• W3000000149 doi "https://doi.org/10.1089/jayao.2019.0131" @default.
• W3000000149 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31916877" @default.
• W3000000149 hasPublicationYear "2020" @default.
• W3000000149 type Work @default.
• W3000000149 sameAs 3000000149 @default.
• W3000000149 citedByCount "1" @default.
• W3000000149 countsByYear W30000001492022 @default.
• W3000000149 crossrefType "journal-article" @default.
• W3000000149 hasAuthorship W3000000149A5010118231 @default.
• W3000000149 hasAuthorship W3000000149A5021513699 @default.
• W3000000149 hasAuthorship W3000000149A5022822432 @default.
• W3000000149 hasAuthorship W3000000149A5025991543 @default.
• W3000000149 hasAuthorship W3000000149A5026538997 @default.
• W3000000149 hasAuthorship W3000000149A5035520605 @default.
• W3000000149 hasAuthorship W3000000149A5041441527 @default.
• W3000000149 hasAuthorship W3000000149A5068808085 @default.
• W3000000149 hasAuthorship W3000000149A5076151504 @default.
• W3000000149 hasBestOaLocation W30000001491 @default.
• W3000000149 hasConcept C119060515 @default.
• W3000000149 hasConcept C126322002 @default.
• W3000000149 hasConcept C207103383 @default.
• W3000000149 hasConcept C2777910003 @default.
• W3000000149 hasConcept C2908647359 @default.
• W3000000149 hasConcept C44249647 @default.
• W3000000149 hasConcept C71924100 @default.
• W3000000149 hasConcept C99454951 @default.
• W3000000149 hasConceptScore W3000000149C119060515 @default.
• W3000000149 hasConceptScore W3000000149C126322002 @default.
• W3000000149 hasConceptScore W3000000149C207103383 @default.
• W3000000149 hasConceptScore W3000000149C2777910003 @default.
• W3000000149 hasConceptScore W3000000149C2908647359 @default.
• W3000000149 hasConceptScore W3000000149C44249647 @default.
• W3000000149 hasConceptScore W3000000149C71924100 @default.
• W3000000149 hasConceptScore W3000000149C99454951 @default.
• W3000000149 hasIssue "3" @default.
• W3000000149 hasLocation W30000001491 @default.
• W3000000149 hasOpenAccess W3000000149 @default.
• W3000000149 hasPrimaryLocation W30000001491 @default.
• W3000000149 hasRelatedWork W2005101102 @default.
• W3000000149 hasRelatedWork W2090763189 @default.
• W3000000149 hasRelatedWork W2154948599 @default.
• W3000000149 hasRelatedWork W2792916732 @default.
• W3000000149 hasRelatedWork W2793335702 @default.
• W3000000149 hasRelatedWork W2913113213 @default.
• W3000000149 hasRelatedWork W3114266572 @default.
• W3000000149 hasRelatedWork W4210646467 @default.
• W3000000149 hasRelatedWork W4254083861 @default.
• W3000000149 hasRelatedWork W4285601951 @default.
• W3000000149 hasVolume "9" @default.
• W3000000149 isParatext "false" @default.
• W3000000149 isRetracted "false" @default.
• W3000000149 magId "3000000149" @default.
• W3000000149 workType "article" @default.