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• W3000089314 abstract "Abstract Resting state functional connectivity (RSFC) reflects the organization of functional networks in the brain. Functional networks measured during “resting”, or task-absent, state are correlated with cognitive function, and much development of these networks occurs between infancy and adulthood. However, RSFC research in the intermediate years (especially between ages 3 and 5 years) has been limited, mainly due to a paucity of child-appropriate neural measures and behavioral paradigms. This paper presents a new paradigm to measure RSFC in young children, utilizing functional near-infrared spectroscopy (fNIRS) and Freeplay, a simple behavioral setup designed to approximate resting state in children. In Experiment 1, we recorded fNIRS data from children aged 3-8 years and adults aged 18-21 years and examined feasibility and validity of our measure of RSFC, and compared measures across the two groups. In Experiment 2, we recorded longitudinal data at two points (approximately 3 months apart) from children aged 3-5 years, and examined reliability under a variety of measures. In both experiments, all children were able to complete testing and provide usable data, a significant improvement over fMRI-based RSFC measurement in children. Results suggest this paradigm is practical and has good construct validity and test-retest reliability, and may contribute towards increasing the availability of reliable data on resting state networks in early childhood. In particular, these are some of the first positive results on the feasibility of reliably measuring functional connectivity in children aged 3-5 years." @default.
• W3000089314 created "2020-01-23" @default.
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• W3000089314 date "2020-01-13" @default.
• W3000089314 modified "2023-10-14" @default.
• W3000089314 title "A Paradigm for Measuring Resting State Functional Connectivity in Young Children Using fNIRS and Freeplay" @default.
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• W3000089314 doi "https://doi.org/10.1101/2020.01.13.904029" @default.
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