FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3000224732> ?p ?o ?g. }

• W3000224732 abstract "Abstract Funding Acknowledgements Samara Governor Grant in the field of science and technics 2018 Essential hypertension (EH) is one of the most important risk factor for major cardiovascular diseases and remains one of the most important medical and social problems in the world. Left ventricle hypertrophy, caused by chronic increased blood pressure, is an important independent risk factor for sudden death, myocardial infarction, stroke and other cardiovascular complications. Catestatin is a peptide, belonging to the buffer system catecholamines-catestatin and changes of its concentrations contribute to early EH pathogenesis. The aim of the research was to evaluate correlations of catestatin concentrations with cardiac remodeling ultrasound traditional criteria in patients with EH of different cardiovascular risk. Material and methods. The study included 180 male patients in age from 30 to 50 years with a diagnosis of EH, who signed an informed consent to participate in the study. Patients were divided into 4 groups – group 1 (n = 28) – EH of an average risk of cardiovascular complications (CVC), group 2 (n = 76) – EH of a high risk of CVC, group 3 (n = 31) – EH of very high risk of CVC and the group of contril – 45 almost healthy men with normal and optimal blood pressure. Transthoracic echocardiography and sonography of the brachiocephalic trunk arteries were performed. The results. Intra-group analysis of the data revealed a statistically significant negative correlation of catestatin concentrations and carotid intima-media thickness of the common carotid artery on the left in group 2 (r=-0,246; p = 0,040). In patients with EH catestatin and left ventricle end-diastolic volume correlations were revealed (r = 0,827; p = 0,011). Intra-group correlation analysis revealed a statistically significant correlation of catestatin concentrations and left ventricle posterior wall thickness (r=-0,523; p = 0,045), interventricular septum thickness (r=-0,523, p = 0,045) in diastole in group 2; with left ventricle posterior wall thickness (r = 0,258; p = 0,035) and interventricular septum thickness (r = 0,254; p = 0,038) in systole in group 3. Correlation analysis of the data discovered a statistically significant negative relationship between catestatin concentrations and left ventricle remodeling (r=-0,171, p = 0,042). In patients with normal heart geometry, statistically significant (p = 0,04) higher concentrations of catestatin were obtained in comparison with patients with left ventricle remodeling (9,05 ± 5,12 vs. 7,49 ± 3,62 ng/ml, respectively). The conclusion. The decrease of catestatin concentrations in patients with EH of a high and very high risk of CVC is associated with cardiovascular remodeling, mediated by hypertenstion. Catestatin can be used in addition to cardiac remodeling ultrasound traditional criteria in patients with essential hypertension." @default.
• W3000224732 created "2020-01-23" @default.
• W3000224732 creator A5042511562 @default.
• W3000224732 creator A5085590596 @default.
• W3000224732 creator A5090867312 @default.
• W3000224732 date "2020-01-01" @default.
• W3000224732 modified "2023-09-27" @default.
• W3000224732 title "P671 Can catestatin be used as an alternative or addition to cardiac remodeling ultrasound traditional criteria in patients with essential hypertension?" @default.
• W3000224732 doi "https://doi.org/10.1093/ehjci/jez319.351" @default.
• W3000224732 hasPublicationYear "2020" @default.
• W3000224732 type Work @default.
• W3000224732 sameAs 3000224732 @default.
• W3000224732 citedByCount "0" @default.
• W3000224732 crossrefType "journal-article" @default.
• W3000224732 hasAuthorship W3000224732A5042511562 @default.
• W3000224732 hasAuthorship W3000224732A5085590596 @default.
• W3000224732 hasAuthorship W3000224732A5090867312 @default.
• W3000224732 hasConcept C126322002 @default.
• W3000224732 hasConcept C127413603 @default.
• W3000224732 hasConcept C164705383 @default.
• W3000224732 hasConcept C2776002628 @default.
• W3000224732 hasConcept C2777097880 @default.
• W3000224732 hasConcept C2778921608 @default.
• W3000224732 hasConcept C2779537366 @default.
• W3000224732 hasConcept C2780645631 @default.
• W3000224732 hasConcept C500558357 @default.
• W3000224732 hasConcept C50440223 @default.
• W3000224732 hasConcept C71924100 @default.
• W3000224732 hasConcept C78519656 @default.
• W3000224732 hasConcept C84393581 @default.
• W3000224732 hasConceptScore W3000224732C126322002 @default.
• W3000224732 hasConceptScore W3000224732C127413603 @default.
• W3000224732 hasConceptScore W3000224732C164705383 @default.
• W3000224732 hasConceptScore W3000224732C2776002628 @default.
• W3000224732 hasConceptScore W3000224732C2777097880 @default.
• W3000224732 hasConceptScore W3000224732C2778921608 @default.
• W3000224732 hasConceptScore W3000224732C2779537366 @default.
• W3000224732 hasConceptScore W3000224732C2780645631 @default.
• W3000224732 hasConceptScore W3000224732C500558357 @default.
• W3000224732 hasConceptScore W3000224732C50440223 @default.
• W3000224732 hasConceptScore W3000224732C71924100 @default.
• W3000224732 hasConceptScore W3000224732C78519656 @default.
• W3000224732 hasConceptScore W3000224732C84393581 @default.
• W3000224732 hasLocation W30002247321 @default.
• W3000224732 hasOpenAccess W3000224732 @default.
• W3000224732 hasPrimaryLocation W30002247321 @default.
• W3000224732 hasRelatedWork W12656572 @default.
• W3000224732 hasRelatedWork W13347425 @default.
• W3000224732 hasRelatedWork W17396976 @default.
• W3000224732 hasRelatedWork W18785979 @default.
• W3000224732 hasRelatedWork W21458193 @default.
• W3000224732 hasRelatedWork W4077518 @default.
• W3000224732 hasRelatedWork W4650811 @default.
• W3000224732 hasRelatedWork W658077 @default.
• W3000224732 hasRelatedWork W10958683 @default.
• W3000224732 hasRelatedWork W11139666 @default.
• W3000224732 isParatext "false" @default.
• W3000224732 isRetracted "false" @default.
• W3000224732 magId "3000224732" @default.
• W3000224732 workType "article" @default.