FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3000305280> ?p ?o ?g. }

• W3000305280 endingPage "108578" @default.
• W3000305280 startingPage "108578" @default.
• W3000305280 abstract "Rabies is a highly lethal infectious zoonosis caused by rabies virus (RABV), and the mortality rate is almost 100 % once clinical symptoms appear, which poses a huge threat to public health security across the many parts of the word. Vaccination is reported to be the most effective approach to prevent the disease. G protein is the only protein present on the surface of RABV, it also could induce humoral immunity to produce virus neutralizing antibodies (VNA) and stimulate T cells to produce cellular immunity. Adeno-associated viruses (AAVs) have been used as vectors for gene therapy of different human diseases for its low immunogenicity, high safety and long-term stable expression. To develop a safe and effective vaccine, recombinant AAVs containing different kind of G gene were constructed. After intramuscular (i.m.) immunization in mice, all of these rAAV-G vaccines could induce the production of high levels of VNA and effective cellular immune response. Consistently, all of the rAAV-G vaccines could provide protection against lethal RABV challenge. Our results shown that the rAAV-G vaccines could be potential candidates used in the control of RABV infection. In addition, rAAV-G as a vaccine has many advantages of low preparation cost, simple storage and transportation conditions (4 °C storage and transportation), simple immunization program (only one immunization) and so on. Thence, the rAAV-G vaccines could be potential candidates used in the control of RABV infection." @default.
• W3000305280 created "2020-01-23" @default.
• W3000305280 creator A5000119683 @default.
• W3000305280 creator A5016117915 @default.
• W3000305280 creator A5020529987 @default.
• W3000305280 creator A5021957184 @default.
• W3000305280 creator A5023036351 @default.
• W3000305280 creator A5027289296 @default.
• W3000305280 creator A5027894940 @default.
• W3000305280 creator A5039996746 @default.
• W3000305280 creator A5057995095 @default.
• W3000305280 creator A5058377072 @default.
• W3000305280 creator A5077945540 @default.
• W3000305280 creator A5082598946 @default.
• W3000305280 date "2020-03-01" @default.
• W3000305280 modified "2023-09-30" @default.
• W3000305280 title "AAV-expressed G protein induces robust humoral and cellular immune response and provides durable protection from rabies virus challenges in mice" @default.
• W3000305280 cites W1515198130 @default.
• W3000305280 cites W1598925812 @default.
• W3000305280 cites W1824389368 @default.
• W3000305280 cites W1931029669 @default.
• W3000305280 cites W1974337744 @default.
• W3000305280 cites W2009031675 @default.
• W3000305280 cites W2019612944 @default.
• W3000305280 cites W2021527318 @default.
• W3000305280 cites W2023962213 @default.
• W3000305280 cites W2028282577 @default.
• W3000305280 cites W2046021971 @default.
• W3000305280 cites W2054599136 @default.
• W3000305280 cites W2067189573 @default.
• W3000305280 cites W2071404720 @default.
• W3000305280 cites W2072539330 @default.
• W3000305280 cites W2077745882 @default.
• W3000305280 cites W2092282307 @default.
• W3000305280 cites W2101458827 @default.
• W3000305280 cites W2105679568 @default.
• W3000305280 cites W2120934662 @default.
• W3000305280 cites W2123821887 @default.
• W3000305280 cites W2133171074 @default.
• W3000305280 cites W2142334980 @default.
• W3000305280 cites W2150832705 @default.
• W3000305280 cites W2159537966 @default.
• W3000305280 cites W2281274272 @default.
• W3000305280 cites W2487691261 @default.
• W3000305280 cites W2727482182 @default.
• W3000305280 cites W2954149152 @default.
• W3000305280 doi "https://doi.org/10.1016/j.vetmic.2020.108578" @default.
• W3000305280 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32122589" @default.
• W3000305280 hasPublicationYear "2020" @default.
• W3000305280 type Work @default.
• W3000305280 sameAs 3000305280 @default.
• W3000305280 citedByCount "6" @default.
• W3000305280 countsByYear W30003052802020 @default.
• W3000305280 countsByYear W30003052802021 @default.
• W3000305280 countsByYear W30003052802022 @default.
• W3000305280 countsByYear W30003052802023 @default.
• W3000305280 crossrefType "journal-article" @default.
• W3000305280 hasAuthorship W3000305280A5000119683 @default.
• W3000305280 hasAuthorship W3000305280A5016117915 @default.
• W3000305280 hasAuthorship W3000305280A5020529987 @default.
• W3000305280 hasAuthorship W3000305280A5021957184 @default.
• W3000305280 hasAuthorship W3000305280A5023036351 @default.
• W3000305280 hasAuthorship W3000305280A5027289296 @default.
• W3000305280 hasAuthorship W3000305280A5027894940 @default.
• W3000305280 hasAuthorship W3000305280A5039996746 @default.
• W3000305280 hasAuthorship W3000305280A5057995095 @default.
• W3000305280 hasAuthorship W3000305280A5058377072 @default.
• W3000305280 hasAuthorship W3000305280A5077945540 @default.
• W3000305280 hasAuthorship W3000305280A5082598946 @default.
• W3000305280 hasConcept C159047783 @default.
• W3000305280 hasConcept C203014093 @default.
• W3000305280 hasConcept C22070199 @default.
• W3000305280 hasConcept C2522874641 @default.
• W3000305280 hasConcept C2776353676 @default.
• W3000305280 hasConcept C2776849203 @default.
• W3000305280 hasConcept C2776872762 @default.
• W3000305280 hasConcept C2777961786 @default.
• W3000305280 hasConcept C2779261636 @default.
• W3000305280 hasConcept C2779341262 @default.
• W3000305280 hasConcept C2780674857 @default.
• W3000305280 hasConcept C2780801004 @default.
• W3000305280 hasConcept C2780868878 @default.
• W3000305280 hasConcept C86803240 @default.
• W3000305280 hasConcept C8891405 @default.
• W3000305280 hasConceptScore W3000305280C159047783 @default.
• W3000305280 hasConceptScore W3000305280C203014093 @default.
• W3000305280 hasConceptScore W3000305280C22070199 @default.
• W3000305280 hasConceptScore W3000305280C2522874641 @default.
• W3000305280 hasConceptScore W3000305280C2776353676 @default.
• W3000305280 hasConceptScore W3000305280C2776849203 @default.
• W3000305280 hasConceptScore W3000305280C2776872762 @default.
• W3000305280 hasConceptScore W3000305280C2777961786 @default.
• W3000305280 hasConceptScore W3000305280C2779261636 @default.
• W3000305280 hasConceptScore W3000305280C2779341262 @default.
• W3000305280 hasConceptScore W3000305280C2780674857 @default.
• W3000305280 hasConceptScore W3000305280C2780801004 @default.
• W3000305280 hasConceptScore W3000305280C2780868878 @default.
• W3000305280 hasConceptScore W3000305280C86803240 @default.

• next