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- W3000321840 abstract "Objective To assess the efficacy of large volumes of diluted intraperitoneal bupivacaine in post-laparoscopic cholecystectomy analgesia. Study design A randomised controlled trial. Place and duration of study Department of General Surgery, Nishtar Hospital, Multan, from August 2018 to June, 2019. Methodology Two equal groups with 55 patients each were formed. Normal saline 500 ml in group A, and mixture of 20 ml 0.5% bupivacaine in 480 ml normal saline in group B, was used to irrigate peritoneal cavity. Final outcome of the study was the comparison of pain-free duration. Postoperatively, numerical rating scale (NRS) score at various intervals and total analgesics requirement within 24 hours after the procedure were included in the secondary outcomes. Student's t-test was applied on continuous data and Pearson's Chi-square test on nominal variables. P >0.05 was considered of no statistical significance. Results Both groups were comparable for age, weight, gender, duration of surgery. Postoperative analgesia duration was 0.99 ± 0.51 hours in group A and 16.53 ±2.65 hours in group-B (p 0.05). Conclusion Large volume of diluted bupivacaine when injected intraperitoneally during laparoscopic cholecystectomy provides prolonged time pain relief." @default.
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- W3000321840 date "2020-01-01" @default.
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- W3000321840 title "Intraperitoneal Bupivacaine as Post-laparoscopic Cholecystectomy Analgesia" @default.
- W3000321840 doi "https://doi.org/10.29271/jcpsp.2020.01.09" @default.
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