Matches in SemOpenAlex for { <https://semopenalex.org/work/W3000328051> ?p ?o ?g. }
- W3000328051 abstract "Abstract The human adult structural connectome has a rich nodal hierarchy, with highly diverse connectivity patterns aligned to the diverse range of functional specializations in the brain. The emergence of this hierarchical complexity in human development is unknown. Here, we substantiate the hierarchical tiers and hierarchical complexity of brain networks in the newborn period; assess correspondences with hierarchical complexity in adulthood; and investigate the effect of preterm birth, a leading cause of atypical brain development and later neurocognitive impairment, on hierarchical complexity. We report that neonatal and adult structural connectomes are both composed of distinct hierarchical tiers, and that hierarchical complexity is greater in term born neonates than in preterms. This is due to diversity of connectivity patterns of regions within the intermediate tiers, which consist of regions that underlie sensorimotor processing and its integration with cognitive information. For neonates and adults, the highest tier (hub regions) is ordered, rather than complex, with more homogeneous connectivity patterns in structural hubs. This suggests that the brain develops first a more rigid structure in hub regions allowing for the development of greater and more diverse functional specialization in lower level regions, while connectivity underpinning this diversity is dysmature in infants born preterm." @default.
- W3000328051 created "2020-01-23" @default.
- W3000328051 creator A5002330647 @default.
- W3000328051 creator A5020530100 @default.
- W3000328051 creator A5024099929 @default.
- W3000328051 creator A5031686647 @default.
- W3000328051 creator A5034776089 @default.
- W3000328051 creator A5039695778 @default.
- W3000328051 creator A5042056955 @default.
- W3000328051 creator A5054787746 @default.
- W3000328051 creator A5054908296 @default.
- W3000328051 creator A5055721719 @default.
- W3000328051 creator A5060254662 @default.
- W3000328051 creator A5066187655 @default.
- W3000328051 date "2020-01-17" @default.
- W3000328051 modified "2023-09-25" @default.
- W3000328051 title "Hierarchical complexity of the macro-scale neonatal brain" @default.
- W3000328051 cites W1449393047 @default.
- W3000328051 cites W1965894642 @default.
- W3000328051 cites W1967159562 @default.
- W3000328051 cites W1970928383 @default.
- W3000328051 cites W1973233713 @default.
- W3000328051 cites W1983208069 @default.
- W3000328051 cites W1984453610 @default.
- W3000328051 cites W1989523430 @default.
- W3000328051 cites W2001611992 @default.
- W3000328051 cites W2003731009 @default.
- W3000328051 cites W2020044743 @default.
- W3000328051 cites W2020519533 @default.
- W3000328051 cites W2024966367 @default.
- W3000328051 cites W2027266940 @default.
- W3000328051 cites W2046142779 @default.
- W3000328051 cites W2057562617 @default.
- W3000328051 cites W2067214598 @default.
- W3000328051 cites W2074732691 @default.
- W3000328051 cites W2077203280 @default.
- W3000328051 cites W2089940272 @default.
- W3000328051 cites W2094435366 @default.
- W3000328051 cites W2101135654 @default.
- W3000328051 cites W2116136260 @default.
- W3000328051 cites W2117340355 @default.
- W3000328051 cites W2120466222 @default.
- W3000328051 cites W2121734518 @default.
- W3000328051 cites W2127309075 @default.
- W3000328051 cites W2131940336 @default.
- W3000328051 cites W2133182819 @default.
- W3000328051 cites W2136573752 @default.
- W3000328051 cites W2148157540 @default.
- W3000328051 cites W2165360032 @default.
- W3000328051 cites W2261948865 @default.
- W3000328051 cites W2470259419 @default.
- W3000328051 cites W2508982726 @default.
- W3000328051 cites W2523692751 @default.
- W3000328051 cites W2526265723 @default.
- W3000328051 cites W2530688037 @default.
- W3000328051 cites W2561810854 @default.
- W3000328051 cites W2578766800 @default.
- W3000328051 cites W2580688057 @default.
- W3000328051 cites W2587965857 @default.
- W3000328051 cites W2594272198 @default.
- W3000328051 cites W2623944053 @default.
- W3000328051 cites W2726168273 @default.
- W3000328051 cites W2760684854 @default.
- W3000328051 cites W2766024669 @default.
- W3000328051 cites W2792313030 @default.
- W3000328051 cites W2808493265 @default.
- W3000328051 cites W2890067656 @default.
- W3000328051 cites W2894385768 @default.
- W3000328051 cites W2898765517 @default.
- W3000328051 cites W2907477685 @default.
- W3000328051 cites W2938544796 @default.
- W3000328051 cites W2944765019 @default.
- W3000328051 cites W2950736313 @default.
- W3000328051 cites W2951129129 @default.
- W3000328051 cites W2951290748 @default.
- W3000328051 cites W2953130519 @default.
- W3000328051 cites W2963176674 @default.
- W3000328051 cites W2973706876 @default.
- W3000328051 cites W2990157246 @default.
- W3000328051 cites W2992205463 @default.
- W3000328051 cites W2997612430 @default.
- W3000328051 cites W2999262508 @default.
- W3000328051 cites W3001023882 @default.
- W3000328051 cites W3009092364 @default.
- W3000328051 cites W3100844160 @default.
- W3000328051 cites W4241568191 @default.
- W3000328051 cites W795339718 @default.
- W3000328051 doi "https://doi.org/10.1101/2020.01.16.909150" @default.
- W3000328051 hasPublicationYear "2020" @default.
- W3000328051 type Work @default.
- W3000328051 sameAs 3000328051 @default.
- W3000328051 citedByCount "1" @default.
- W3000328051 countsByYear W30003280512022 @default.
- W3000328051 crossrefType "posted-content" @default.
- W3000328051 hasAuthorship W3000328051A5002330647 @default.
- W3000328051 hasAuthorship W3000328051A5020530100 @default.
- W3000328051 hasAuthorship W3000328051A5024099929 @default.
- W3000328051 hasAuthorship W3000328051A5031686647 @default.
- W3000328051 hasAuthorship W3000328051A5034776089 @default.
- W3000328051 hasAuthorship W3000328051A5039695778 @default.