Matches in SemOpenAlex for { <https://semopenalex.org/work/W3000447130> ?p ?o ?g. }
- W3000447130 abstract "Abstract Detailed conductance-based nonlinear neuron models consisting of thousands of synapses are key for understanding of the computational properties of single neurons and large neuronal networks, and for interpreting experimental results. Simulations of these models are computationally expensive, considerably curtailing their utility. Neuron_Reduce is a new analytical approach to reduce the morphological complexity and computational time of nonlinear neuron models. Synapses and active membrane channels are mapped to the reduced model preserving their transfer impedance to the soma; synapses with identical transfer impedance are merged into one NEURON process still retaining their individual activation times. Neuron_Reduce accelerates the simulations by 40–250 folds for a variety of cell types and realistic number (10,000–100,000) of synapses while closely replicating voltage dynamics and specific dendritic computations. The reduced neuron-models will enable realistic simulations of neural networks at unprecedented scale, including networks emerging from micro-connectomics efforts and biologically-inspired “deep networks”. Neuron_Reduce is publicly available and is straightforward to implement." @default.
- W3000447130 created "2020-01-23" @default.
- W3000447130 creator A5006914267 @default.
- W3000447130 creator A5010345378 @default.
- W3000447130 creator A5016582959 @default.
- W3000447130 creator A5025022011 @default.
- W3000447130 creator A5026165241 @default.
- W3000447130 creator A5082740542 @default.
- W3000447130 creator A5088028124 @default.
- W3000447130 date "2020-01-15" @default.
- W3000447130 modified "2023-10-02" @default.
- W3000447130 title "An efficient analytical reduction of detailed nonlinear neuron models" @default.
- W3000447130 cites W1486735428 @default.
- W3000447130 cites W1528942588 @default.
- W3000447130 cites W1566861944 @default.
- W3000447130 cites W1589243260 @default.
- W3000447130 cites W1603186852 @default.
- W3000447130 cites W1817362523 @default.
- W3000447130 cites W1921182138 @default.
- W3000447130 cites W1967038391 @default.
- W3000447130 cites W1971689790 @default.
- W3000447130 cites W1977632372 @default.
- W3000447130 cites W2000509838 @default.
- W3000447130 cites W2001429889 @default.
- W3000447130 cites W2009951703 @default.
- W3000447130 cites W2011301426 @default.
- W3000447130 cites W2012174917 @default.
- W3000447130 cites W2025695585 @default.
- W3000447130 cites W2026890501 @default.
- W3000447130 cites W2032841135 @default.
- W3000447130 cites W2034654633 @default.
- W3000447130 cites W2036021747 @default.
- W3000447130 cites W2040407982 @default.
- W3000447130 cites W2042421964 @default.
- W3000447130 cites W2057613746 @default.
- W3000447130 cites W2058670052 @default.
- W3000447130 cites W2059256607 @default.
- W3000447130 cites W2077587321 @default.
- W3000447130 cites W2088955805 @default.
- W3000447130 cites W2118213643 @default.
- W3000447130 cites W2121324852 @default.
- W3000447130 cites W2140885691 @default.
- W3000447130 cites W2140886546 @default.
- W3000447130 cites W2143816834 @default.
- W3000447130 cites W2144925492 @default.
- W3000447130 cites W2153797761 @default.
- W3000447130 cites W2154421570 @default.
- W3000447130 cites W2155364286 @default.
- W3000447130 cites W2160988512 @default.
- W3000447130 cites W2168025484 @default.
- W3000447130 cites W2275340749 @default.
- W3000447130 cites W2406265206 @default.
- W3000447130 cites W2408793726 @default.
- W3000447130 cites W2466282698 @default.
- W3000447130 cites W2529356830 @default.
- W3000447130 cites W2533823091 @default.
- W3000447130 cites W2790354390 @default.
- W3000447130 cites W2807113328 @default.
- W3000447130 cites W2885652098 @default.
- W3000447130 cites W2889897651 @default.
- W3000447130 cites W2890240030 @default.
- W3000447130 cites W2950651308 @default.
- W3000447130 cites W2950958538 @default.
- W3000447130 cites W2951043812 @default.
- W3000447130 cites W2953248462 @default.
- W3000447130 cites W2963259006 @default.
- W3000447130 cites W2963967818 @default.
- W3000447130 cites W3099967679 @default.
- W3000447130 cites W3124915050 @default.
- W3000447130 cites W318388308 @default.
- W3000447130 cites W4214775604 @default.
- W3000447130 doi "https://doi.org/10.1038/s41467-019-13932-6" @default.
- W3000447130 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6962154" @default.
- W3000447130 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31941884" @default.
- W3000447130 hasPublicationYear "2020" @default.
- W3000447130 type Work @default.
- W3000447130 sameAs 3000447130 @default.
- W3000447130 citedByCount "20" @default.
- W3000447130 countsByYear W30004471302020 @default.
- W3000447130 countsByYear W30004471302021 @default.
- W3000447130 countsByYear W30004471302022 @default.
- W3000447130 countsByYear W30004471302023 @default.
- W3000447130 crossrefType "journal-article" @default.
- W3000447130 hasAuthorship W3000447130A5006914267 @default.
- W3000447130 hasAuthorship W3000447130A5010345378 @default.
- W3000447130 hasAuthorship W3000447130A5016582959 @default.
- W3000447130 hasAuthorship W3000447130A5025022011 @default.
- W3000447130 hasAuthorship W3000447130A5026165241 @default.
- W3000447130 hasAuthorship W3000447130A5082740542 @default.
- W3000447130 hasAuthorship W3000447130A5088028124 @default.
- W3000447130 hasBestOaLocation W30004471301 @default.
- W3000447130 hasConcept C111335779 @default.
- W3000447130 hasConcept C11413529 @default.
- W3000447130 hasConcept C121332964 @default.
- W3000447130 hasConcept C154945302 @default.
- W3000447130 hasConcept C158622935 @default.
- W3000447130 hasConcept C169760540 @default.
- W3000447130 hasConcept C186060115 @default.
- W3000447130 hasConcept C186565885 @default.
- W3000447130 hasConcept C2524010 @default.