FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3000484255> ?p ?o ?g. }

• W3000484255 endingPage "2183" @default.
• W3000484255 startingPage "2175" @default.
• W3000484255 abstract "PURPOSE Characterization of leakage indices on ultra-widefield fluorescein angiography in proliferative diabetic retinopathy treated with intravitreal aflibercept. METHODS Prospective study enrolling subjects for treatment of proliferative diabetic retinopathy randomized 1:1 to receive 2-mg intravitreal aflibercept every 4 weeks (2q4) or every 12 weeks (2q12). Ultra-widefield fluorescein angiography images obtained at baseline, 24, and 48 weeks were analyzed using a semiautomated leakage segmentation platform. Panretinal and zonal leakage indices were calculated. RESULTS Forty eyes of 40 subjects were included, and mean age was 48 ± 12.1 years. Mean number of injections was 11 ± 1.7 in the 2q4 arm and 4 ± 0.4 in the 2q12 arm. Median baseline leakage index in the 2q4 and 2q12 groups was 5.1% and 4.3%, respectively (P = 0.28). At 24 and 48 weeks, the 2q4 group significantly improved to 1.1% (-79%, P < 0.0001). At Week 24, the 2q12 group demonstrated nonsignificant improvement (3.4%; -21%, P = 0.47); by Week 48, improvement was significant (1.4%; -68%, P = 0.02). The 2q4 group resulted in lower leakage index compared with the 2q12 group at 24 weeks (1.1% vs. 3.4%, respectively; P = 0.008), but by 48 weeks, leakage index was similar between both groups (1.1% vs. 1.4%, respectively; P = 0.34). CONCLUSION Proliferative diabetic retinopathy treated with intravitreal aflibercept demonstrated significant leakage index reductions at 1 year. Monthly dosing provided more rapid reduction in leakage index compared with quarterly dosing. TRIAL REGISTRATION RECOVERY study (NCT02863354); https://clinicaltrials.gov/ct2/show/NCT02863354." @default.
• W3000484255 created "2020-01-23" @default.
• W3000484255 creator A5002996984 @default.
• W3000484255 creator A5017527346 @default.
• W3000484255 creator A5036549169 @default.
• W3000484255 creator A5048325594 @default.
• W3000484255 creator A5051960536 @default.
• W3000484255 creator A5060701866 @default.
• W3000484255 creator A5072863451 @default.
• W3000484255 creator A5073193063 @default.
• W3000484255 creator A5087846232 @default.
• W3000484255 date "2020-01-08" @default.
• W3000484255 modified "2023-10-15" @default.
• W3000484255 title "RETINAL LEAKAGE INDEX DYNAMICS ON ULTRA-WIDEFIELD FLUORESCEIN ANGIOGRAPHY IN EYES TREATED WITH INTRAVITREAL AFLIBERCEPT FOR PROLIFERATIVE DIABETIC RETINOPATHY IN THE RECOVERY STUDY" @default.
• W3000484255 cites W1627947970 @default.
• W3000484255 cites W1915008606 @default.
• W3000484255 cites W1933504035 @default.
• W3000484255 cites W1972499026 @default.
• W3000484255 cites W1999957425 @default.
• W3000484255 cites W2099558473 @default.
• W3000484255 cites W2127013658 @default.
• W3000484255 cites W2144088749 @default.
• W3000484255 cites W2273205327 @default.
• W3000484255 cites W2277325960 @default.
• W3000484255 cites W2313571009 @default.
• W3000484255 cites W2314257879 @default.
• W3000484255 cites W2336107249 @default.
• W3000484255 cites W2509900411 @default.
• W3000484255 cites W2580283010 @default.
• W3000484255 cites W2606329851 @default.
• W3000484255 cites W2616361514 @default.
• W3000484255 cites W2620609902 @default.
• W3000484255 cites W2781990999 @default.
• W3000484255 cites W2790761319 @default.
• W3000484255 cites W2792886111 @default.
• W3000484255 cites W2883798682 @default.
• W3000484255 cites W2884222000 @default.
• W3000484255 cites W4240531687 @default.
• W3000484255 cites W922383587 @default.
• W3000484255 doi "https://doi.org/10.1097/iae.0000000000002727" @default.
• W3000484255 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31917731" @default.
• W3000484255 hasPublicationYear "2020" @default.
• W3000484255 type Work @default.
• W3000484255 sameAs 3000484255 @default.
• W3000484255 citedByCount "9" @default.
• W3000484255 countsByYear W30004842552021 @default.
• W3000484255 countsByYear W30004842552022 @default.
• W3000484255 countsByYear W30004842552023 @default.
• W3000484255 crossrefType "journal-article" @default.
• W3000484255 hasAuthorship W3000484255A5002996984 @default.
• W3000484255 hasAuthorship W3000484255A5017527346 @default.
• W3000484255 hasAuthorship W3000484255A5036549169 @default.
• W3000484255 hasAuthorship W3000484255A5048325594 @default.
• W3000484255 hasAuthorship W3000484255A5051960536 @default.
• W3000484255 hasAuthorship W3000484255A5060701866 @default.
• W3000484255 hasAuthorship W3000484255A5072863451 @default.
• W3000484255 hasAuthorship W3000484255A5073193063 @default.
• W3000484255 hasAuthorship W3000484255A5087846232 @default.
• W3000484255 hasConcept C118487528 @default.
• W3000484255 hasConcept C120665830 @default.
• W3000484255 hasConcept C121332964 @default.
• W3000484255 hasConcept C134018914 @default.
• W3000484255 hasConcept C139719470 @default.
• W3000484255 hasConcept C141071460 @default.
• W3000484255 hasConcept C162324750 @default.
• W3000484255 hasConcept C2776694085 @default.
• W3000484255 hasConcept C2777042071 @default.
• W3000484255 hasConcept C2777802072 @default.
• W3000484255 hasConcept C2778015030 @default.
• W3000484255 hasConcept C2778313320 @default.
• W3000484255 hasConcept C2778749236 @default.
• W3000484255 hasConcept C2779829184 @default.
• W3000484255 hasConcept C2780248432 @default.
• W3000484255 hasConcept C2780827179 @default.
• W3000484255 hasConcept C555293320 @default.
• W3000484255 hasConcept C71924100 @default.
• W3000484255 hasConcept C91881484 @default.
• W3000484255 hasConceptScore W3000484255C118487528 @default.
• W3000484255 hasConceptScore W3000484255C120665830 @default.
• W3000484255 hasConceptScore W3000484255C121332964 @default.
• W3000484255 hasConceptScore W3000484255C134018914 @default.
• W3000484255 hasConceptScore W3000484255C139719470 @default.
• W3000484255 hasConceptScore W3000484255C141071460 @default.
• W3000484255 hasConceptScore W3000484255C162324750 @default.
• W3000484255 hasConceptScore W3000484255C2776694085 @default.
• W3000484255 hasConceptScore W3000484255C2777042071 @default.
• W3000484255 hasConceptScore W3000484255C2777802072 @default.
• W3000484255 hasConceptScore W3000484255C2778015030 @default.
• W3000484255 hasConceptScore W3000484255C2778313320 @default.
• W3000484255 hasConceptScore W3000484255C2778749236 @default.
• W3000484255 hasConceptScore W3000484255C2779829184 @default.
• W3000484255 hasConceptScore W3000484255C2780248432 @default.
• W3000484255 hasConceptScore W3000484255C2780827179 @default.
• W3000484255 hasConceptScore W3000484255C555293320 @default.
• W3000484255 hasConceptScore W3000484255C71924100 @default.
• W3000484255 hasConceptScore W3000484255C91881484 @default.
• W3000484255 hasIssue "11" @default.
• W3000484255 hasLocation W30004842551 @default.

• next