Matches in SemOpenAlex for { <https://semopenalex.org/work/W3000491815> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W3000491815 endingPage "1541" @default.
- W3000491815 startingPage "1541" @default.
- W3000491815 abstract "The role of direct-acting oral anticoagulants in the treatment of venous thromboembolism (VTE) in cancer patients compared with the current standard of low-molecular-weight heparin (LMWH) treatment remains unclear. This meta-analysis aimed to evaluate the efficacy and safety of direct factor Xa inhibitors compared with those of LMWH in the treatment of cancer-associated VTE.We systematically searched PubMed, EMBASE, Cochrane library, and Web of Science for potential randomized controlled clinical trials and retrospective cohort studies. Data on recurrent VTE (efficacy) and major and minor bleeding events (safety) were extracted, and the odds risks (OR) were analyzed using a random-effect model.A total of nine studies involving 4208 cancer patients with VTE were included in these analyses. Pooled analysis showed that direct factor Xa inhibitors were significantly superior to LMWH in reducing the risk of recurrent VTE (OR = 0.67; 95% confidence interval [CI]: 0.54-0.82). There was no significant difference in the rate of major bleeding between the direct factor Xa inhibitor and LMWH treatments (OR = 1.25; 95% CI: 0.94-1.65). However, the rate of minor bleeding events was higher when a direct factor Xa inhibitor was used instead of LMWH (OR = 1.80; 95% CI: 1.05-3.07).Direct factor Xa inhibitors are superior to LMWH in efficacy in the treatment of VTE in cancer patients, and the safety between the two regimens is comparable except for a slightly higher rate of minor bleeding when the former is used." @default.
- W3000491815 created "2020-01-23" @default.
- W3000491815 creator A5011412144 @default.
- W3000491815 creator A5011681788 @default.
- W3000491815 creator A5022832205 @default.
- W3000491815 creator A5025575277 @default.
- W3000491815 creator A5031767034 @default.
- W3000491815 creator A5046600167 @default.
- W3000491815 creator A5058259187 @default.
- W3000491815 creator A5065850508 @default.
- W3000491815 date "2019-01-01" @default.
- W3000491815 modified "2023-10-18" @default.
- W3000491815 title "Comparison between direct factor Xa inhibitors and low-molecular-weight heparin for efficacy and safety in the treatment of cancer-associated venous thromboembolism: A meta-analysis" @default.
- W3000491815 cites W1827812019 @default.
- W3000491815 cites W1981316005 @default.
- W3000491815 cites W2210532669 @default.
- W3000491815 cites W2225937646 @default.
- W3000491815 cites W2333514251 @default.
- W3000491815 cites W2467202497 @default.
- W3000491815 cites W2471363772 @default.
- W3000491815 cites W2561678837 @default.
- W3000491815 cites W2588687036 @default.
- W3000491815 cites W2736900730 @default.
- W3000491815 cites W2752516637 @default.
- W3000491815 cites W2765286649 @default.
- W3000491815 cites W2766875361 @default.
- W3000491815 cites W2775434460 @default.
- W3000491815 cites W2793035957 @default.
- W3000491815 cites W2795588879 @default.
- W3000491815 cites W2802130786 @default.
- W3000491815 cites W2810981907 @default.
- W3000491815 cites W2901744711 @default.
- W3000491815 doi "https://doi.org/10.4103/jcrt.jcrt_68_19" @default.
- W3000491815 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31939435" @default.
- W3000491815 hasPublicationYear "2019" @default.
- W3000491815 type Work @default.
- W3000491815 sameAs 3000491815 @default.
- W3000491815 citedByCount "4" @default.
- W3000491815 countsByYear W30004918152020 @default.
- W3000491815 countsByYear W30004918152021 @default.
- W3000491815 countsByYear W30004918152023 @default.
- W3000491815 crossrefType "journal-article" @default.
- W3000491815 hasAuthorship W3000491815A5011412144 @default.
- W3000491815 hasAuthorship W3000491815A5011681788 @default.
- W3000491815 hasAuthorship W3000491815A5022832205 @default.
- W3000491815 hasAuthorship W3000491815A5025575277 @default.
- W3000491815 hasAuthorship W3000491815A5031767034 @default.
- W3000491815 hasAuthorship W3000491815A5046600167 @default.
- W3000491815 hasAuthorship W3000491815A5058259187 @default.
- W3000491815 hasAuthorship W3000491815A5065850508 @default.
- W3000491815 hasBestOaLocation W30004918151 @default.
- W3000491815 hasConcept C121608353 @default.
- W3000491815 hasConcept C126322002 @default.
- W3000491815 hasConcept C141071460 @default.
- W3000491815 hasConcept C143998085 @default.
- W3000491815 hasConcept C156957248 @default.
- W3000491815 hasConcept C2776478404 @default.
- W3000491815 hasConcept C2776884760 @default.
- W3000491815 hasConcept C2777557582 @default.
- W3000491815 hasConcept C2780868729 @default.
- W3000491815 hasConcept C2991741193 @default.
- W3000491815 hasConcept C50440223 @default.
- W3000491815 hasConcept C71924100 @default.
- W3000491815 hasConcept C95190672 @default.
- W3000491815 hasConceptScore W3000491815C121608353 @default.
- W3000491815 hasConceptScore W3000491815C126322002 @default.
- W3000491815 hasConceptScore W3000491815C141071460 @default.
- W3000491815 hasConceptScore W3000491815C143998085 @default.
- W3000491815 hasConceptScore W3000491815C156957248 @default.
- W3000491815 hasConceptScore W3000491815C2776478404 @default.
- W3000491815 hasConceptScore W3000491815C2776884760 @default.
- W3000491815 hasConceptScore W3000491815C2777557582 @default.
- W3000491815 hasConceptScore W3000491815C2780868729 @default.
- W3000491815 hasConceptScore W3000491815C2991741193 @default.
- W3000491815 hasConceptScore W3000491815C50440223 @default.
- W3000491815 hasConceptScore W3000491815C71924100 @default.
- W3000491815 hasConceptScore W3000491815C95190672 @default.
- W3000491815 hasIssue "7" @default.
- W3000491815 hasLocation W30004918151 @default.
- W3000491815 hasLocation W30004918152 @default.
- W3000491815 hasOpenAccess W3000491815 @default.
- W3000491815 hasPrimaryLocation W30004918151 @default.
- W3000491815 hasRelatedWork W2025923048 @default.
- W3000491815 hasRelatedWork W2276107796 @default.
- W3000491815 hasRelatedWork W2353652576 @default.
- W3000491815 hasRelatedWork W2359825457 @default.
- W3000491815 hasRelatedWork W2903486660 @default.
- W3000491815 hasRelatedWork W3116417372 @default.
- W3000491815 hasRelatedWork W3150135412 @default.
- W3000491815 hasRelatedWork W4291824836 @default.
- W3000491815 hasRelatedWork W4311672127 @default.
- W3000491815 hasRelatedWork W4366779626 @default.
- W3000491815 hasVolume "15" @default.
- W3000491815 isParatext "false" @default.
- W3000491815 isRetracted "false" @default.
- W3000491815 magId "3000491815" @default.
- W3000491815 workType "article" @default.