FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3000524409> ?p ?o ?g. }

• W3000524409 endingPage "249" @default.
• W3000524409 startingPage "249" @default.
• W3000524409 abstract "Morinda citrifolia, a fruit generally known as “Noni”, has been traditionally used in parts of East Asia to relieve inflammatory diseases. Although several studies using noni have been reported, the effect of fermented Morinda citrifolia (F.NONI) on atopic dermatitis (AD) has not been investigated. Thus, we aimed to investigate the improving effect of F.NONI treatment on AD-like skin lesions and elucidate molecular mechanisms. F.NONI was prepared by the fermentation of noni fruit with probiotics and then extracted. F.NONI was orally administrated to NC/Nga mice to evaluate its therapeutic effect on 2,4-dinitrochlorobenzene (DNCB)-induced AD. Oral administration of F.NONI significantly alleviated AD lesions and symptoms such as dermatitis scores, ear thickness, scratching behavior, epidermal thickness, and infiltration of inflammatory cells (e.g., mast cells and eosinophils). In addition, F.NONI treatment reduced the levels of histamine, IgE and IgG1/IgG2a ratio, thymus and activation regulated chemokine (TARC), and thymic stromal lymphopoietin (TSLP) in serum and beneficially modulated the expressions of Th1, Th2, Th17, and Th22-mediated cytokines in lesioned skin and splenocytes. Furthermore, the expressions of the skin barrier-related proteins including filaggrin (FLG), loricrin (LOR), involucrin (IVL), zonula occludens-1 (ZO-1), and occludin (OCC) were restored by F.NONI treatment. Taken together, these results suggest that F.NONI could be a therapeutic agent to attenuate AD-like skin lesions through modulating the immune balance and skin barrier function." @default.
• W3000524409 created "2020-01-23" @default.
• W3000524409 creator A5015164764 @default.
• W3000524409 creator A5067103599 @default.
• W3000524409 creator A5069167592 @default.
• W3000524409 date "2020-01-18" @default.
• W3000524409 modified "2023-10-13" @default.
• W3000524409 title "Fermented Morinda citrifolia (Noni) Alleviates DNCB-Induced Atopic Dermatitis in NC/Nga Mice through Modulating Immune Balance and Skin Barrier Function" @default.
• W3000524409 cites W1606922774 @default.
• W3000524409 cites W1749560059 @default.
• W3000524409 cites W1915760257 @default.
• W3000524409 cites W1964354952 @default.
• W3000524409 cites W1970140945 @default.
• W3000524409 cites W1977549443 @default.
• W3000524409 cites W1982673677 @default.
• W3000524409 cites W1983682342 @default.
• W3000524409 cites W198427113 @default.
• W3000524409 cites W1987628377 @default.
• W3000524409 cites W1992001694 @default.
• W3000524409 cites W1993832226 @default.
• W3000524409 cites W1994262603 @default.
• W3000524409 cites W2002797131 @default.
• W3000524409 cites W2012727632 @default.
• W3000524409 cites W2013340393 @default.
• W3000524409 cites W2020186773 @default.
• W3000524409 cites W2024193200 @default.
• W3000524409 cites W2026124542 @default.
• W3000524409 cites W2030946322 @default.
• W3000524409 cites W2035183016 @default.
• W3000524409 cites W2041243178 @default.
• W3000524409 cites W2041619734 @default.
• W3000524409 cites W2043287196 @default.
• W3000524409 cites W2044739547 @default.
• W3000524409 cites W2045189254 @default.
• W3000524409 cites W2049625834 @default.
• W3000524409 cites W2054570534 @default.
• W3000524409 cites W2063748338 @default.
• W3000524409 cites W2065746239 @default.
• W3000524409 cites W2068137660 @default.
• W3000524409 cites W2070316318 @default.
• W3000524409 cites W2077529892 @default.
• W3000524409 cites W2084224801 @default.
• W3000524409 cites W2114978456 @default.
• W3000524409 cites W2119621206 @default.
• W3000524409 cites W2126612550 @default.
• W3000524409 cites W2134261811 @default.
• W3000524409 cites W2135881977 @default.
• W3000524409 cites W2137722996 @default.
• W3000524409 cites W2153318588 @default.
• W3000524409 cites W2162201817 @default.
• W3000524409 cites W2169192341 @default.
• W3000524409 cites W2174132185 @default.
• W3000524409 cites W2264329878 @default.
• W3000524409 cites W2328856618 @default.
• W3000524409 cites W2402117629 @default.
• W3000524409 cites W2474553364 @default.
• W3000524409 cites W2491278258 @default.
• W3000524409 cites W2491281233 @default.
• W3000524409 cites W2496806206 @default.
• W3000524409 cites W2576901056 @default.
• W3000524409 cites W2604389567 @default.
• W3000524409 cites W2606085194 @default.
• W3000524409 cites W2623738179 @default.
• W3000524409 cites W2769875674 @default.
• W3000524409 cites W2790119072 @default.
• W3000524409 cites W2791136704 @default.
• W3000524409 cites W2792353660 @default.
• W3000524409 cites W2883351316 @default.
• W3000524409 cites W2885267330 @default.
• W3000524409 cites W2906695700 @default.
• W3000524409 cites W4246863005 @default.
• W3000524409 doi "https://doi.org/10.3390/nu12010249" @default.
• W3000524409 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7019744" @default.
• W3000524409 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31963703" @default.
• W3000524409 hasPublicationYear "2020" @default.
• W3000524409 type Work @default.
• W3000524409 sameAs 3000524409 @default.
• W3000524409 citedByCount "26" @default.
• W3000524409 countsByYear W30005244092020 @default.
• W3000524409 countsByYear W30005244092021 @default.
• W3000524409 countsByYear W30005244092022 @default.
• W3000524409 countsByYear W30005244092023 @default.
• W3000524409 crossrefType "journal-article" @default.
• W3000524409 hasAuthorship W3000524409A5015164764 @default.
• W3000524409 hasAuthorship W3000524409A5067103599 @default.
• W3000524409 hasAuthorship W3000524409A5069167592 @default.
• W3000524409 hasBestOaLocation W30005244091 @default.
• W3000524409 hasConcept C164027704 @default.
• W3000524409 hasConcept C177779419 @default.
• W3000524409 hasConcept C185592680 @default.
• W3000524409 hasConcept C202751555 @default.
• W3000524409 hasConcept C203014093 @default.
• W3000524409 hasConcept C2775962179 @default.
• W3000524409 hasConcept C2776008674 @default.
• W3000524409 hasConcept C2776914184 @default.
• W3000524409 hasConcept C2777074287 @default.
• W3000524409 hasConcept C2777577635 @default.
• W3000524409 hasConcept C2778070265 @default.

• next