FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3000566943> ?p ?o ?g. }

• W3000566943 abstract "Abstract Background Randomised controlled trials (RCTs) provide the most reliable information to inform clinical practice and patient care. We aimed to map global clinical research publication activity through RCT-related articles in high-impact-factor medical journals over the past five decades. Methods We conducted a cross-sectional analysis of articles published in the highest ranked medical journals with an impact factor > 10 (according to Journal Citation Reports published in 2017). We searched PubMed/MEDLINE (from inception to December 31, 2017) for all RCT-related articles (e.g. primary RCTs, secondary analyses and methodology papers) published in high-impact-factor medical journals. For each included article, raw metadata were abstracted from the Web of Science. A process of standardization was conducted to unify the different terms and grammatical variants and to remove typographical, transcription and/or indexing errors. Descriptive analyses were conducted (including the number of articles, citations, most prolific authors, countries, journals, funding sources and keywords). Network analyses of collaborations between countries and co-words are presented. Results We included 39,305 articles (for the period 1965–2017) published in forty journals. The Lancet ( n = 3593; 9.1%), the Journal of Clinical Oncology ( n = 3343; 8.5%) and The New England Journal of Medicine ( n = 3275 articles; 8.3%) published the largest number of RCTs. A total of 154 countries were involved in the production of articles. The global productivity ranking was led by the United States ( n = 18,393 articles), followed by the United Kingdom ( n = 8028 articles), Canada ( n = 4548 articles) and Germany ( n = 4415 articles). Seventeen authors who had published 100 or more articles were identified; the most prolific authors were affiliated with Duke University (United States), Harvard University (United States) and McMaster University (Canada). The main funding institutions were the National Institutes of Health (United States), Hoffmann-La Roche (Switzerland), Pfizer (United States), Merck Sharp & Dohme (United States) and Novartis (Switzerland). The 100 most cited RCTs were published in nine journals, led by The New England Journal of Medicine ( n = 78 articles), The Lancet ( n = 9 articles) and JAMA ( n = 7 articles). These landmark contributions focused on novel methodological approaches (e.g. the “Bland-Altman method”) and trials on the management of chronic conditions (e.g. diabetes control, hormone replacement therapy in postmenopausal women, multiple therapies for diverse cancers, cardiovascular therapies such as lipid-lowering statins, antihypertensive medications, and antiplatelet and antithrombotic therapy). Conclusions Our analysis identified authors, countries, funding institutions, landmark contributions and high-impact-factor medical journals publishing RCTs. Over the last 50 years, publication production in leading medical journals has increased, with Western countries leading in research but with low- and middle-income countries showing very limited representation." @default.
• W3000566943 created "2020-01-23" @default.
• W3000566943 creator A5003813907 @default.
• W3000566943 creator A5019787474 @default.
• W3000566943 creator A5045231943 @default.
• W3000566943 creator A5050215170 @default.
• W3000566943 creator A5060373660 @default.
• W3000566943 creator A5068353058 @default.
• W3000566943 creator A5082962371 @default.
• W3000566943 date "2020-01-07" @default.
• W3000566943 modified "2023-10-18" @default.
• W3000566943 title "Global mapping of randomised trials related articles published in high-impact-factor medical journals: a cross-sectional analysis" @default.
• W3000566943 cites W1553345686 @default.
• W3000566943 cites W1593442063 @default.
• W3000566943 cites W172609984 @default.
• W3000566943 cites W1767553509 @default.
• W3000566943 cites W180946569 @default.
• W3000566943 cites W1966936568 @default.
• W3000566943 cites W1971837077 @default.
• W3000566943 cites W1982375973 @default.
• W3000566943 cites W1996802760 @default.
• W3000566943 cites W2002062153 @default.
• W3000566943 cites W2002265699 @default.
• W3000566943 cites W2003756366 @default.
• W3000566943 cites W2005871247 @default.
• W3000566943 cites W2015795623 @default.
• W3000566943 cites W2022936635 @default.
• W3000566943 cites W2023155726 @default.
• W3000566943 cites W2025776410 @default.
• W3000566943 cites W2029149928 @default.
• W3000566943 cites W2031739072 @default.
• W3000566943 cites W2039964888 @default.
• W3000566943 cites W2044591801 @default.
• W3000566943 cites W2050381689 @default.
• W3000566943 cites W2056976690 @default.
• W3000566943 cites W2065625460 @default.
• W3000566943 cites W2077472090 @default.
• W3000566943 cites W2081814119 @default.
• W3000566943 cites W2092669241 @default.
• W3000566943 cites W2096287682 @default.
• W3000566943 cites W2096644655 @default.
• W3000566943 cites W2097995306 @default.
• W3000566943 cites W2099877908 @default.
• W3000566943 cites W2104109727 @default.
• W3000566943 cites W2106952837 @default.
• W3000566943 cites W2111561507 @default.
• W3000566943 cites W2111582355 @default.
• W3000566943 cites W2113264115 @default.
• W3000566943 cites W2122293881 @default.
• W3000566943 cites W2128542677 @default.
• W3000566943 cites W2129167322 @default.
• W3000566943 cites W2136489990 @default.
• W3000566943 cites W2141647078 @default.
• W3000566943 cites W2144504916 @default.
• W3000566943 cites W2149199716 @default.
• W3000566943 cites W2152240392 @default.
• W3000566943 cites W2152789823 @default.
• W3000566943 cites W2152904388 @default.
• W3000566943 cites W2154423984 @default.
• W3000566943 cites W2155598961 @default.
• W3000566943 cites W2156098321 @default.
• W3000566943 cites W2157769714 @default.
• W3000566943 cites W2157990810 @default.
• W3000566943 cites W2158822657 @default.
• W3000566943 cites W2159438841 @default.
• W3000566943 cites W2159977622 @default.
• W3000566943 cites W2160284109 @default.
• W3000566943 cites W2166023752 @default.
• W3000566943 cites W2188846692 @default.
• W3000566943 cites W2259348130 @default.
• W3000566943 cites W2271771390 @default.
• W3000566943 cites W2274253041 @default.
• W3000566943 cites W2289548208 @default.
• W3000566943 cites W2292308933 @default.
• W3000566943 cites W2302447233 @default.
• W3000566943 cites W2312388685 @default.
• W3000566943 cites W2318605753 @default.
• W3000566943 cites W2322095705 @default.
• W3000566943 cites W2323458614 @default.
• W3000566943 cites W2332951586 @default.
• W3000566943 cites W2337454357 @default.
• W3000566943 cites W246286872 @default.
• W3000566943 cites W2469738428 @default.
• W3000566943 cites W2475261460 @default.
• W3000566943 cites W2495547003 @default.
• W3000566943 cites W2512252587 @default.
• W3000566943 cites W2520965749 @default.
• W3000566943 cites W2551517111 @default.
• W3000566943 cites W2615684303 @default.
• W3000566943 cites W2623257747 @default.
• W3000566943 cites W2737491053 @default.
• W3000566943 cites W2745605347 @default.
• W3000566943 cites W2751792491 @default.
• W3000566943 cites W2769264260 @default.
• W3000566943 cites W2790735892 @default.
• W3000566943 cites W2790873746 @default.
• W3000566943 cites W2799372226 @default.
• W3000566943 cites W2802264281 @default.
• W3000566943 cites W2884313467 @default.
• W3000566943 cites W2892633782 @default.

• next