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- W3000618963 abstract "Biodegradable polymeric micelles have potential therapeutic applications; nevertheless, preparing micelles of a specific diameter and uniform size distribution is a challenge. Micelles were formed from the copolymer of poly(ε-caprolactone)-poly(ethylene glycol)-poly(ε-caprolactone) and the effect of PCEC molecular weight, PCL/PEG ratio, solvent-water miscibility, solvent concentration on particle size, polydispersity index and zeta potential of micelles were also investigated. The average particle sizes of the PCEC micelles ranged between 225–959 and 232–1211 nm for micelles prepared with acetone and dimethylformamide, respectively. The encapsulation efficiency is 78.98%. These results indicate that PCEC micelles can be used as drug carriers in controlled delivery systems." @default.
- W3000618963 created "2020-01-23" @default.
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- W3000618963 date "2020-01-13" @default.
- W3000618963 modified "2023-10-03" @default.
- W3000618963 title "Preparation and optimization of biodegradable self-assembled PCL-PEG-PCL nano-sized micelles for drug delivery systems" @default.
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- W3000618963 doi "https://doi.org/10.1080/00914037.2020.1713784" @default.
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