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- W3000648514 abstract "A 72-year-old man with pancreatic cancer presented with coffee-ground emesis for 2 days. Computed tomography of abdomen with oral contrast showed gastric distention, with transition point at level of the bulb and large volume ascites. Endoscopy showed severe diffuse exudative esophagitis involving most of the esophagus and areas of black discoloration of the mid and distal edematous esophagus (Figures A and B). A large infiltrating mass, consistent with the known pancreatic cancer, was noted in the distal second part of the duodenum obstructing the duodenal lumen (Figures C). Patient was kept nil per orally and started on intravenous pantoprazole and intravenous hydration. Acute esophageal necrosis (AEN), also known as black esophagus, is a rare clinical condition with a prevalence of 0.001% to 0.2%. It is diagnosed endoscopically and characterized by diffuse circumferential black necrotic esophageal mucosa that universally affects distal esophagus and stops at gastroesophageal junction (Figures D). It is more common in men, and mortality ranges from 13% to 35%. Distal esophagus is watershed area, which explains the typical location of AEN. Pathogenesis involves 2-hit hypothesis (esophageal ischemia and gastric outlet obstruction). AEN is associated with malignancy, gastric outlet obstruction, and prolonged vomiting. Although AEN is rare, early diagnosis and treatment increase chances of survival." @default.
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- W3000648514 date "2021-02-01" @default.
- W3000648514 modified "2023-10-14" @default.
- W3000648514 title "Black Esophagus Due to Acute Necrosis" @default.
- W3000648514 doi "https://doi.org/10.1016/j.cgh.2019.12.039" @default.
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