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- W3000677923 abstract "We report the case of a 25-year-old woman who developed temporal lobe epilepsy associated with systemic lupus erythematosus (SLE). Serum and cerebrospinal fluid samples showed high titers of anti-ribosomal P (anti-P) antibodies with negative anti-NMDAR antibodies. She was receiving prednisone and azathioprine, with normalization of SLE serum markers, but without changes in titers of anti-P antibodies. No seizure control was achieved using valproic acid, levetiracetam and lamotrigine. However, she had a selective response to topiramate, an AMPAR blocker, maintained during 6 years of follow-up. We discuss the pathophysiology of this autoimmune epilepsy associated with high titer anti-P antibodies." @default.
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- W3000677923 date "2020-03-01" @default.
- W3000677923 modified "2023-09-23" @default.
- W3000677923 title "Refractory epilepsy associated with anti-ribosomal P antibodies successfully treated with topiramate" @default.
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- W3000677923 doi "https://doi.org/10.1016/j.jneuroim.2020.577144" @default.
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