Matches in SemOpenAlex for { <https://semopenalex.org/work/W3000769969> ?p ?o ?g. }
- W3000769969 abstract "The joint is a complex anatomical structure consisting of different tissues, each with a particular feature, playing together to give mobility and stability at the body. All the joints have a similar composition including cartilage for reducing the friction of the movement and protect the underlying bone, a synovial membrane that produces synovial fluid to lubricate the joint, ligaments to limit joint movement and tendons for the interaction with muscles. Direct or indirect damage of one or more of the tissues forming the joint is the foundation of different pathological conditions. Many molecular mechanisms are involved in maintaining the joint homeostasis as well as in triggering a pathological condition. The molecular pathway activated by the purinergic system is one of them. The purinergic signaling defines a group of receptors and intermembrane channels activated by adenosine, adenosine diphosphate and adenosine 5’-triphosphate. It has been largely described as a modulator of many physiological and pathological conditions including rheumatic diseases. Here we will give an overview of the purinergic system in the joint describing its expression and function in the synovium, cartilage, ligament, tendon and bone with a therapeutic perspective." @default.
- W3000769969 created "2020-01-30" @default.
- W3000769969 creator A5001694046 @default.
- W3000769969 creator A5059516590 @default.
- W3000769969 date "2020-01-24" @default.
- W3000769969 modified "2023-10-14" @default.
- W3000769969 title "Signaling of the Purinergic System in the Joint" @default.
- W3000769969 cites W1412498810 @default.
- W3000769969 cites W1485133278 @default.
- W3000769969 cites W1521173359 @default.
- W3000769969 cites W1524500351 @default.
- W3000769969 cites W1536932676 @default.
- W3000769969 cites W1560781154 @default.
- W3000769969 cites W1573984805 @default.
- W3000769969 cites W1595299996 @default.
- W3000769969 cites W1730594841 @default.
- W3000769969 cites W1832128547 @default.
- W3000769969 cites W1848620583 @default.
- W3000769969 cites W1863013769 @default.
- W3000769969 cites W1932870409 @default.
- W3000769969 cites W1968714897 @default.
- W3000769969 cites W1970143992 @default.
- W3000769969 cites W1970811141 @default.
- W3000769969 cites W1971170473 @default.
- W3000769969 cites W1971719973 @default.
- W3000769969 cites W1971817436 @default.
- W3000769969 cites W1972199068 @default.
- W3000769969 cites W1972317443 @default.
- W3000769969 cites W1975346943 @default.
- W3000769969 cites W1976961529 @default.
- W3000769969 cites W1977897934 @default.
- W3000769969 cites W1979043688 @default.
- W3000769969 cites W1982767795 @default.
- W3000769969 cites W1983654099 @default.
- W3000769969 cites W1985080645 @default.
- W3000769969 cites W1987465314 @default.
- W3000769969 cites W1989486586 @default.
- W3000769969 cites W1994600783 @default.
- W3000769969 cites W1994703283 @default.
- W3000769969 cites W1999675383 @default.
- W3000769969 cites W2001493385 @default.
- W3000769969 cites W2008299531 @default.
- W3000769969 cites W2008926173 @default.
- W3000769969 cites W2009350215 @default.
- W3000769969 cites W2012147245 @default.
- W3000769969 cites W2015255171 @default.
- W3000769969 cites W2022112190 @default.
- W3000769969 cites W2024227894 @default.
- W3000769969 cites W2025212116 @default.
- W3000769969 cites W2026522326 @default.
- W3000769969 cites W2027712657 @default.
- W3000769969 cites W2030040603 @default.
- W3000769969 cites W2030178482 @default.
- W3000769969 cites W2031930652 @default.
- W3000769969 cites W2034321048 @default.
- W3000769969 cites W2036287567 @default.
- W3000769969 cites W2036402991 @default.
- W3000769969 cites W2036950738 @default.
- W3000769969 cites W2037869778 @default.
- W3000769969 cites W2038595980 @default.
- W3000769969 cites W2039410576 @default.
- W3000769969 cites W2040487992 @default.
- W3000769969 cites W2042863008 @default.
- W3000769969 cites W2042906495 @default.
- W3000769969 cites W2045463244 @default.
- W3000769969 cites W2048087267 @default.
- W3000769969 cites W2051275990 @default.
- W3000769969 cites W2054310788 @default.
- W3000769969 cites W2056244474 @default.
- W3000769969 cites W2059030264 @default.
- W3000769969 cites W2059079363 @default.
- W3000769969 cites W2059751568 @default.
- W3000769969 cites W2062490687 @default.
- W3000769969 cites W2066227639 @default.
- W3000769969 cites W2068358413 @default.
- W3000769969 cites W2068569140 @default.
- W3000769969 cites W2070849951 @default.
- W3000769969 cites W2073206342 @default.
- W3000769969 cites W2073537081 @default.
- W3000769969 cites W2075345875 @default.
- W3000769969 cites W2075551405 @default.
- W3000769969 cites W2078187027 @default.
- W3000769969 cites W2078624814 @default.
- W3000769969 cites W2082417162 @default.
- W3000769969 cites W2083602463 @default.
- W3000769969 cites W2083920483 @default.
- W3000769969 cites W2084337108 @default.
- W3000769969 cites W2085460371 @default.
- W3000769969 cites W2085498155 @default.
- W3000769969 cites W2085607766 @default.
- W3000769969 cites W2085753048 @default.
- W3000769969 cites W2085931935 @default.
- W3000769969 cites W2086723448 @default.
- W3000769969 cites W2087917186 @default.
- W3000769969 cites W2088844806 @default.
- W3000769969 cites W2089370986 @default.
- W3000769969 cites W2089802506 @default.
- W3000769969 cites W2094344379 @default.
- W3000769969 cites W2094693257 @default.
- W3000769969 cites W2094926250 @default.