FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3000809145> ?p ?o ?g. }

• W3000809145 endingPage "136940" @default.
• W3000809145 startingPage "136940" @default.
• W3000809145 abstract "As global climate changes, mass mortality in farmed fish associated with the severely cold weather has aroused growing concerns. Yellow drum (Nibea albiflora) is an important maricultured fish in China, whereby its aquaculture suffered from overwinter mortality associated with cold and cold-induced-fasting stresses. Here, by using LC-MS metabolomics combined with transcriptomics, we investigated the physiological responses of yellow drum liver to cold and starvation stresses. The experiment involved four groups: 16 °C fed group (CG1), 16 °C unfed group (CG2), 8 °C fed group (EG1), and 8 °C unfed group (EG2). Under cold stress, a total of 308 and 257 differential metabolites were identified in EG1 vs. CG1 and EG2 vs. CG2, respectively, showing 5 overlapping significant pathways: glutathione metabolism, biosynthesis of unsaturated fatty acids, galactose metabolism, arginine and proline metabolism, and ABC transporters. Intersection analysis identified that glutamate, oxidized glutathione (GSSG), and eicosenoic acid were the common metabolites induced by cold stress. Under starvation stress, a total of 300 and 215 differential metabolites were identified in CG2 vs. CG1 and EG2 vs. EG1, respectively, showing 2 overlapping significant pathways: glutathione metabolism and galactose metabolism. Intersection analysis revealed that glutamate and GSSG were the common metabolites caused by fasting. Under cold and starvation combined stresses, 286 differential metabolites were identified in EG2 vs. CG1, showing 7 influenced pathways: glycerophospholipid metabolism, biosynthesis of unsaturated fatty acids, glutathione metabolism, sphingolipid metabolism, glycosylphosphatidylinositol (GPI)-anchor biosynthesis, autophagy, and purine metabolism. Interestingly, the glutamate and GSSG were induced by both single and combined stresses of cold and starvation treatments. These findings suggest that glutathione metabolism and its related metabolites (glutamate and GSSG) could be potential biomarkers of cold and starvation stresses in yellow drum. Overall, the results of this study provided insights into the physiological regulation in response to cold and starvation stresses in this fish." @default.
• W3000809145 created "2020-01-30" @default.
• W3000809145 creator A5030367743 @default.
• W3000809145 creator A5060227045 @default.
• W3000809145 creator A5070410939 @default.
• W3000809145 creator A5075254066 @default.
• W3000809145 creator A5086357154 @default.
• W3000809145 date "2020-05-01" @default.
• W3000809145 modified "2023-10-16" @default.
• W3000809145 title "Physiological responses to cold and starvation stresses in the liver of yellow drum (Nibea albiflora) revealed by LC-MS metabolomics" @default.
• W3000809145 cites W1503760388 @default.
• W3000809145 cites W1891967301 @default.
• W3000809145 cites W1953959955 @default.
• W3000809145 cites W1996221314 @default.
• W3000809145 cites W1996483501 @default.
• W3000809145 cites W2015745609 @default.
• W3000809145 cites W2018786455 @default.
• W3000809145 cites W2020101627 @default.
• W3000809145 cites W2023832179 @default.
• W3000809145 cites W2025774390 @default.
• W3000809145 cites W2038917714 @default.
• W3000809145 cites W2059365427 @default.
• W3000809145 cites W2060592426 @default.
• W3000809145 cites W2061304346 @default.
• W3000809145 cites W2063102255 @default.
• W3000809145 cites W2080094749 @default.
• W3000809145 cites W2088662115 @default.
• W3000809145 cites W2123111228 @default.
• W3000809145 cites W2134789936 @default.
• W3000809145 cites W2136061619 @default.
• W3000809145 cites W2147179608 @default.
• W3000809145 cites W2147690605 @default.
• W3000809145 cites W2162624684 @default.
• W3000809145 cites W2163581659 @default.
• W3000809145 cites W2396325846 @default.
• W3000809145 cites W2470421132 @default.
• W3000809145 cites W2515712756 @default.
• W3000809145 cites W2556683882 @default.
• W3000809145 cites W2584589733 @default.
• W3000809145 cites W2749841120 @default.
• W3000809145 cites W2793659866 @default.
• W3000809145 cites W2805149367 @default.
• W3000809145 cites W2827056258 @default.
• W3000809145 cites W2894822569 @default.
• W3000809145 cites W2913153345 @default.
• W3000809145 cites W2945624389 @default.
• W3000809145 cites W2949158040 @default.
• W3000809145 cites W2962573626 @default.
• W3000809145 cites W581071236 @default.
• W3000809145 doi "https://doi.org/10.1016/j.scitotenv.2020.136940" @default.
• W3000809145 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32014771" @default.
• W3000809145 hasPublicationYear "2020" @default.
• W3000809145 type Work @default.
• W3000809145 sameAs 3000809145 @default.
• W3000809145 citedByCount "59" @default.
• W3000809145 countsByYear W30008091452020 @default.
• W3000809145 countsByYear W30008091452021 @default.
• W3000809145 countsByYear W30008091452022 @default.
• W3000809145 countsByYear W30008091452023 @default.
• W3000809145 crossrefType "journal-article" @default.
• W3000809145 hasAuthorship W3000809145A5030367743 @default.
• W3000809145 hasAuthorship W3000809145A5060227045 @default.
• W3000809145 hasAuthorship W3000809145A5070410939 @default.
• W3000809145 hasAuthorship W3000809145A5075254066 @default.
• W3000809145 hasAuthorship W3000809145A5086357154 @default.
• W3000809145 hasConcept C104317684 @default.
• W3000809145 hasConcept C134018914 @default.
• W3000809145 hasConcept C181199279 @default.
• W3000809145 hasConcept C192989942 @default.
• W3000809145 hasConcept C21565614 @default.
• W3000809145 hasConcept C2776991927 @default.
• W3000809145 hasConcept C2780606744 @default.
• W3000809145 hasConcept C538909803 @default.
• W3000809145 hasConcept C553450214 @default.
• W3000809145 hasConcept C55493867 @default.
• W3000809145 hasConcept C60644358 @default.
• W3000809145 hasConcept C62231903 @default.
• W3000809145 hasConcept C86803240 @default.
• W3000809145 hasConceptScore W3000809145C104317684 @default.
• W3000809145 hasConceptScore W3000809145C134018914 @default.
• W3000809145 hasConceptScore W3000809145C181199279 @default.
• W3000809145 hasConceptScore W3000809145C192989942 @default.
• W3000809145 hasConceptScore W3000809145C21565614 @default.
• W3000809145 hasConceptScore W3000809145C2776991927 @default.
• W3000809145 hasConceptScore W3000809145C2780606744 @default.
• W3000809145 hasConceptScore W3000809145C538909803 @default.
• W3000809145 hasConceptScore W3000809145C553450214 @default.
• W3000809145 hasConceptScore W3000809145C55493867 @default.
• W3000809145 hasConceptScore W3000809145C60644358 @default.
• W3000809145 hasConceptScore W3000809145C62231903 @default.
• W3000809145 hasConceptScore W3000809145C86803240 @default.
• W3000809145 hasFunder F4320321001 @default.
• W3000809145 hasFunder F4320329971 @default.
• W3000809145 hasFunder F4320333596 @default.
• W3000809145 hasLocation W30008091451 @default.
• W3000809145 hasLocation W30008091452 @default.
• W3000809145 hasOpenAccess W3000809145 @default.
• W3000809145 hasPrimaryLocation W30008091451 @default.

• next