Matches in SemOpenAlex for { <https://semopenalex.org/work/W3001010293> ?p ?o ?g. }
- W3001010293 endingPage "1452" @default.
- W3001010293 startingPage "1443" @default.
- W3001010293 abstract "Membrane lipid composition is known to influence aggregation and fibril formation of many amyloidogenic proteins. Here, we found that phosphatidylethanolamine (PE) accelerates aggregation of the N‐terminal 1‒83 fragment of an amyloidogenic G26R variant of apoA‐I on lipid membranes. Circular dichroism and isothermal titration calorimetry measurements demonstrated that PE does not affect the α‐helical structure and lipid binding property of apoA‐I 1‐83/G26R. Rather, fluorescence measurements indicated that PE induces more ordered lipid packing at the interfacial and acyl chain regions, providing more hydrophobic environments especially around the highly amyloidogenic regions in apoA‐I on the membrane surface. These results suggest that PE promotes aggregation of the amyloidogenic N‐terminal fragment of apoA‐I on lipid membranes by inducing hydrophobic membrane environments." @default.
- W3001010293 created "2020-01-30" @default.
- W3001010293 creator A5000539432 @default.
- W3001010293 creator A5011929881 @default.
- W3001010293 creator A5021925208 @default.
- W3001010293 creator A5023563217 @default.
- W3001010293 creator A5035434445 @default.
- W3001010293 creator A5045702511 @default.
- W3001010293 creator A5046435618 @default.
- W3001010293 creator A5063121188 @default.
- W3001010293 date "2020-02-04" @default.
- W3001010293 modified "2023-09-27" @default.
- W3001010293 title "Phosphatidylethanolamine accelerates aggregation of the amyloidogenic N‐terminal fragment of apoA‐I" @default.
- W3001010293 cites W1229372959 @default.
- W3001010293 cites W1517181973 @default.
- W3001010293 cites W156678813 @default.
- W3001010293 cites W1568596575 @default.
- W3001010293 cites W1965031981 @default.
- W3001010293 cites W1969130034 @default.
- W3001010293 cites W1972701314 @default.
- W3001010293 cites W1979744619 @default.
- W3001010293 cites W1981426567 @default.
- W3001010293 cites W1985992988 @default.
- W3001010293 cites W1987870033 @default.
- W3001010293 cites W1997822065 @default.
- W3001010293 cites W2003889403 @default.
- W3001010293 cites W2005016304 @default.
- W3001010293 cites W2013064076 @default.
- W3001010293 cites W2013939958 @default.
- W3001010293 cites W2017114341 @default.
- W3001010293 cites W2021267305 @default.
- W3001010293 cites W2033967322 @default.
- W3001010293 cites W2034969727 @default.
- W3001010293 cites W2038392139 @default.
- W3001010293 cites W2038942796 @default.
- W3001010293 cites W2041424325 @default.
- W3001010293 cites W2044465436 @default.
- W3001010293 cites W2047354259 @default.
- W3001010293 cites W2050886257 @default.
- W3001010293 cites W2053925151 @default.
- W3001010293 cites W2063174765 @default.
- W3001010293 cites W2070004512 @default.
- W3001010293 cites W2072675976 @default.
- W3001010293 cites W2073593094 @default.
- W3001010293 cites W2077107650 @default.
- W3001010293 cites W2079945911 @default.
- W3001010293 cites W2080764176 @default.
- W3001010293 cites W2114685914 @default.
- W3001010293 cites W2141462626 @default.
- W3001010293 cites W2144556032 @default.
- W3001010293 cites W2149081087 @default.
- W3001010293 cites W2150999725 @default.
- W3001010293 cites W2160497181 @default.
- W3001010293 cites W2163655701 @default.
- W3001010293 cites W2175680864 @default.
- W3001010293 cites W2194585050 @default.
- W3001010293 cites W2225657959 @default.
- W3001010293 cites W2251310087 @default.
- W3001010293 cites W2314605806 @default.
- W3001010293 cites W2324640940 @default.
- W3001010293 cites W2326783367 @default.
- W3001010293 cites W2403174476 @default.
- W3001010293 cites W2542928159 @default.
- W3001010293 cites W2560541065 @default.
- W3001010293 cites W2606007784 @default.
- W3001010293 cites W2768826512 @default.
- W3001010293 cites W2789590064 @default.
- W3001010293 cites W2796318176 @default.
- W3001010293 cites W2799684154 @default.
- W3001010293 cites W2800851386 @default.
- W3001010293 cites W2802332024 @default.
- W3001010293 cites W2810061704 @default.
- W3001010293 cites W2945580339 @default.
- W3001010293 cites W2949718907 @default.
- W3001010293 cites W2962919606 @default.
- W3001010293 doi "https://doi.org/10.1002/1873-3468.13737" @default.
- W3001010293 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31968125" @default.
- W3001010293 hasPublicationYear "2020" @default.
- W3001010293 type Work @default.
- W3001010293 sameAs 3001010293 @default.
- W3001010293 citedByCount "2" @default.
- W3001010293 countsByYear W30010102932022 @default.
- W3001010293 countsByYear W30010102932023 @default.
- W3001010293 crossrefType "journal-article" @default.
- W3001010293 hasAuthorship W3001010293A5000539432 @default.
- W3001010293 hasAuthorship W3001010293A5011929881 @default.
- W3001010293 hasAuthorship W3001010293A5021925208 @default.
- W3001010293 hasAuthorship W3001010293A5023563217 @default.
- W3001010293 hasAuthorship W3001010293A5035434445 @default.
- W3001010293 hasAuthorship W3001010293A5045702511 @default.
- W3001010293 hasAuthorship W3001010293A5046435618 @default.
- W3001010293 hasAuthorship W3001010293A5063121188 @default.
- W3001010293 hasBestOaLocation W30010102931 @default.
- W3001010293 hasConcept C107565407 @default.
- W3001010293 hasConcept C12554922 @default.
- W3001010293 hasConcept C133571119 @default.
- W3001010293 hasConcept C144647389 @default.
- W3001010293 hasConcept C156911925 @default.