FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3001017029> ?p ?o ?g. }

• W3001017029 endingPage "1310" @default.
• W3001017029 startingPage "1303" @default.
• W3001017029 abstract "Purpose To compare early postoperative intraocular pressure (IOP) in patients who underwent cataract surgery alone with those who underwent cataract surgery combined with implantation of a Hydrus Microstent (HMS) (Ivantis, Irvine, CA). Design Subanalysis of data from the randomized controlled HORIZON trial, a multicenter trial including 26 US and 12 international sites. Participants Participants with mild/moderate primary open-angle glaucoma (POAG) and visually significant cataract with mean modified diurnal IOP between 22 and 34 mmHg after washout of IOP-lowering medications. Methods A total of 556 subjects were randomized in a 2:1 ratio to undergo cataract surgery with placement of the HMS versus cataract surgery alone (no microstent [NMS]). All eyes were washed out of IOP-lowering medications before surgery and remained unmedicated until surgery. No IOP-lowering prophylaxis was used postoperatively. Comprehensive eye examination including measurement of intraocular pressure was conducted on postoperative day (POD) 1, week 1, and month 1. Main Outcome Measures Postoperative IOP >40 mmHg was analyzed as the primary outcome. Incidence of IOP increase >10 mmHg above baseline, unmedicated IOP, and mean IOP were analyzed as secondary outcomes. Results A total of 369 eyes were randomized to the HMS group, and 187 eyes were randomized to cataract surgery alone. The HMS and NMS groups did not differ with respect to baseline demographic or ocular characteristics. On POD1, the incidence of IOP spike >40 mmHg was significantly higher at 14.4% in the NMS group compared with 1.4% in the HMS group (P < 0.001). The incidence of IOP increase ≥10 mmHg relative to baseline on POD1 was also significantly higher in the NMS group than in the HMS group (22.5% vs. 3.0%, P < 0.001). IOP in the NMS group was significantly higher than in the HMS group (27.6 vs. 17.0 mmHg, P < 0.001). In multivariable logistic regression analysis, higher baseline IOP predicted higher odds of POD1 IOP spike >40 mmHg, whereas the presence of HMS was associated with a lower likelihood of postoperative IOP spike. Conclusions The addition of an HMS at the time of cataract surgery lowered the risk of markedly elevated IOP in the early postoperative period in patients with glaucoma. To compare early postoperative intraocular pressure (IOP) in patients who underwent cataract surgery alone with those who underwent cataract surgery combined with implantation of a Hydrus Microstent (HMS) (Ivantis, Irvine, CA). Subanalysis of data from the randomized controlled HORIZON trial, a multicenter trial including 26 US and 12 international sites. Participants with mild/moderate primary open-angle glaucoma (POAG) and visually significant cataract with mean modified diurnal IOP between 22 and 34 mmHg after washout of IOP-lowering medications. A total of 556 subjects were randomized in a 2:1 ratio to undergo cataract surgery with placement of the HMS versus cataract surgery alone (no microstent [NMS]). All eyes were washed out of IOP-lowering medications before surgery and remained unmedicated until surgery. No IOP-lowering prophylaxis was used postoperatively. Comprehensive eye examination including measurement of intraocular pressure was conducted on postoperative day (POD) 1, week 1, and month 1. Postoperative IOP >40 mmHg was analyzed as the primary outcome. Incidence of IOP increase >10 mmHg above baseline, unmedicated IOP, and mean IOP were analyzed as secondary outcomes. A total of 369 eyes were randomized to the HMS group, and 187 eyes were randomized to cataract surgery alone. The HMS and NMS groups did not differ with respect to baseline demographic or ocular characteristics. On POD1, the incidence of IOP spike >40 mmHg was significantly higher at 14.4% in the NMS group compared with 1.4% in the HMS group (P < 0.001). The incidence of IOP increase ≥10 mmHg relative to baseline on POD1 was also significantly higher in the NMS group than in the HMS group (22.5% vs. 3.0%, P < 0.001). IOP in the NMS group was significantly higher than in the HMS group (27.6 vs. 17.0 mmHg, P < 0.001). In multivariable logistic regression analysis, higher baseline IOP predicted higher odds of POD1 IOP spike >40 mmHg, whereas the presence of HMS was associated with a lower likelihood of postoperative IOP spike. The addition of an HMS at the time of cataract surgery lowered the risk of markedly elevated IOP in the early postoperative period in patients with glaucoma." @default.
• W3001017029 created "2020-01-30" @default.
• W3001017029 creator A5019049183 @default.
• W3001017029 creator A5031869576 @default.
• W3001017029 creator A5050030287 @default.
• W3001017029 date "2020-10-01" @default.
• W3001017029 modified "2023-10-03" @default.
• W3001017029 title "Effect of a Schlemm’s Canal Microstent on Early Postoperative Intraocular Pressure after Cataract Surgery" @default.
• W3001017029 cites W1969782468 @default.
• W3001017029 cites W1973503527 @default.
• W3001017029 cites W1983422848 @default.
• W3001017029 cites W1993476253 @default.
• W3001017029 cites W1996046261 @default.
• W3001017029 cites W2020385565 @default.
• W3001017029 cites W2037257936 @default.
• W3001017029 cites W2046293632 @default.
• W3001017029 cites W2049724887 @default.
• W3001017029 cites W2055741851 @default.
• W3001017029 cites W2065017201 @default.
• W3001017029 cites W2065142041 @default.
• W3001017029 cites W2067257237 @default.
• W3001017029 cites W2082426453 @default.
• W3001017029 cites W2098997107 @default.
• W3001017029 cites W2107002124 @default.
• W3001017029 cites W2109199409 @default.
• W3001017029 cites W2110897487 @default.
• W3001017029 cites W2118776025 @default.
• W3001017029 cites W2132365080 @default.
• W3001017029 cites W2133588813 @default.
• W3001017029 cites W2148890166 @default.
• W3001017029 cites W2203544737 @default.
• W3001017029 cites W2578889491 @default.
• W3001017029 cites W2781673216 @default.
• W3001017029 cites W2790371490 @default.
• W3001017029 cites W2810579927 @default.
• W3001017029 cites W2903467075 @default.
• W3001017029 cites W4242731554 @default.
• W3001017029 cites W4246878943 @default.
• W3001017029 cites W4297755600 @default.
• W3001017029 doi "https://doi.org/10.1016/j.ophtha.2020.01.025" @default.
• W3001017029 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32143828" @default.
• W3001017029 hasPublicationYear "2020" @default.
• W3001017029 type Work @default.
• W3001017029 sameAs 3001017029 @default.
• W3001017029 citedByCount "8" @default.
• W3001017029 countsByYear W30010170292020 @default.
• W3001017029 countsByYear W30010170292021 @default.
• W3001017029 countsByYear W30010170292022 @default.
• W3001017029 countsByYear W30010170292023 @default.
• W3001017029 crossrefType "journal-article" @default.
• W3001017029 hasAuthorship W3001017029A5019049183 @default.
• W3001017029 hasAuthorship W3001017029A5031869576 @default.
• W3001017029 hasAuthorship W3001017029A5050030287 @default.
• W3001017029 hasConcept C118487528 @default.
• W3001017029 hasConcept C120665830 @default.
• W3001017029 hasConcept C121332964 @default.
• W3001017029 hasConcept C141071460 @default.
• W3001017029 hasConcept C168563851 @default.
• W3001017029 hasConcept C2775888743 @default.
• W3001017029 hasConcept C2776766258 @default.
• W3001017029 hasConcept C2778527774 @default.
• W3001017029 hasConcept C2780186721 @default.
• W3001017029 hasConcept C2781092963 @default.
• W3001017029 hasConcept C2781121420 @default.
• W3001017029 hasConcept C61511704 @default.
• W3001017029 hasConcept C71924100 @default.
• W3001017029 hasConceptScore W3001017029C118487528 @default.
• W3001017029 hasConceptScore W3001017029C120665830 @default.
• W3001017029 hasConceptScore W3001017029C121332964 @default.
• W3001017029 hasConceptScore W3001017029C141071460 @default.
• W3001017029 hasConceptScore W3001017029C168563851 @default.
• W3001017029 hasConceptScore W3001017029C2775888743 @default.
• W3001017029 hasConceptScore W3001017029C2776766258 @default.
• W3001017029 hasConceptScore W3001017029C2778527774 @default.
• W3001017029 hasConceptScore W3001017029C2780186721 @default.
• W3001017029 hasConceptScore W3001017029C2781092963 @default.
• W3001017029 hasConceptScore W3001017029C2781121420 @default.
• W3001017029 hasConceptScore W3001017029C61511704 @default.
• W3001017029 hasConceptScore W3001017029C71924100 @default.
• W3001017029 hasIssue "10" @default.
• W3001017029 hasLocation W30010170291 @default.
• W3001017029 hasOpenAccess W3001017029 @default.
• W3001017029 hasPrimaryLocation W30010170291 @default.
• W3001017029 hasRelatedWork W1964379507 @default.
• W3001017029 hasRelatedWork W2130385907 @default.
• W3001017029 hasRelatedWork W2405094532 @default.
• W3001017029 hasRelatedWork W2781673216 @default.
• W3001017029 hasRelatedWork W2968272251 @default.
• W3001017029 hasRelatedWork W3176735208 @default.
• W3001017029 hasRelatedWork W4212912258 @default.
• W3001017029 hasRelatedWork W4298007858 @default.
• W3001017029 hasRelatedWork W4322742682 @default.
• W3001017029 hasRelatedWork W2186002764 @default.
• W3001017029 hasVolume "127" @default.
• W3001017029 isParatext "false" @default.
• W3001017029 isRetracted "false" @default.
• W3001017029 magId "3001017029" @default.
• W3001017029 workType "article" @default.