Matches in SemOpenAlex for { <https://semopenalex.org/work/W3001032298> ?p ?o ?g. }
- W3001032298 endingPage "8" @default.
- W3001032298 startingPage "1" @default.
- W3001032298 abstract "Background. This article attempts to evaluate the clinical profile and outcome determinants following hypertensive SICH in a South Indian population. The study represents the largest series of SICH reported from a single centre in India. Materials and Methods. Prospective data collection and analysis of patients with SICH admitted to our centre between 1 st January 2015 and 31 st December 2018. The variables analysed include: age, sex, comorbidities, Glasgow coma score (GCS) on admission, radiological features, treatment modality, and outcome at three months. Modified Rankin score (mRS) was used to assess the outcome at discharge and three months. Results. Our study group of 905 patients included 638 males and 267 females and the mean age at presentation was 58.10 ± 12.76 years. The study group included 523 patients (57.8%) previously diagnosed hypertensive, of whom 36.3% (<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M1><mml:mrow><mml:mi>n</mml:mi><mml:mo>=</mml:mo><mml:mn>190</mml:mn></mml:mrow></mml:math>) were on irregular medication. The most frequent locations of hematoma were basal ganglia (478), thalamus (202), lobar (106), cerebellar (61), brainstem (31), and primary intraventricular haemorrhage (27). Secondary intraventricular extension was seen in 425 (47%) patients on admission. The mean volume of the clot on admission was 23.45 ± 19.79 ml, and clot progression was seen in only 46 (5.08%) cases. Surgical evacuation through craniotomy was done in 147 (16.8%) patients, and external ventricular drainage (EVD) was placed in 56 (6.2%) patients. Overall 3−month mortality was 30.1% (266 patients). On the last follow up a favorable outcome (mRS 0−3) was observed in 412 (45.53%) patients and a poor outcome (mRS 4−5) in 207 patients (22.87%). Independent predictors of mortality are Age >70 (<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M2><mml:mrow><mml:mi>p</mml:mi><mml:mo>=</mml:mo><mml:mo><</mml:mo><mml:mn>0.001</mml:mn></mml:mrow></mml:math>, OR 4.806, 95% CI 3.064–7.54), admission GCS <8 (<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M3><mml:mrow><mml:mi>p</mml:mi><mml:mo>=</mml:mo><mml:mo><</mml:mo><mml:mn>0.001</mml:mn></mml:mrow></mml:math>, OR7.684, 95% CI 5.055#x2013;11.68), and Hematoma volume >30 ml (<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M4><mml:mrow><mml:mi>p</mml:mi><mml:mo>=</mml:mo><mml:mo><</mml:mo><mml:mn>0.001</mml:mn></mml:mrow></mml:math>, OR 2.45, 95% CI 1.626–3.691). Intraventricular haemorrhage was an additional poor outcome predictor (<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M5><mml:mrow><mml:mi>p</mml:mi><mml:mo><</mml:mo><mml:mn>0.015</mml:mn></mml:mrow></mml:math>, CI 1.105–2.585). Surgical evacuation reduced mortality in the group, but morbidity rates remained the same. Conclusions. SICH predominantly affects a younger population in India in comparison to the Western society. Elderly age, poor GCS on admission, clot volume above 30 ml and intraventricular extension remain the most consistent predictors of death and poor outcome. Further studies are needed to assess the risk of SICH among hypertensive patients and to prognosticate the outcome after SICH using novel predictors, including biomarkers." @default.
- W3001032298 created "2020-01-30" @default.
- W3001032298 creator A5031651158 @default.
- W3001032298 creator A5039858148 @default.
- W3001032298 creator A5040082618 @default.
- W3001032298 creator A5067912188 @default.
- W3001032298 creator A5077447377 @default.
- W3001032298 creator A5087465928 @default.
- W3001032298 creator A5089914269 @default.
- W3001032298 date "2020-01-27" @default.
- W3001032298 modified "2023-10-01" @default.
- W3001032298 title "Clinical Profile and Predictors of Outcome in Spontaneous Intracerebral Hemorrhage from a Tertiary Care Centre in South India" @default.
- W3001032298 cites W1947113872 @default.
- W3001032298 cites W1976280787 @default.
- W3001032298 cites W1978200938 @default.
- W3001032298 cites W1981283465 @default.
- W3001032298 cites W2014749957 @default.
- W3001032298 cites W2040994497 @default.
- W3001032298 cites W2041891185 @default.
- W3001032298 cites W2075974903 @default.
- W3001032298 cites W2087257939 @default.
- W3001032298 cites W2094585602 @default.
- W3001032298 cites W2100331049 @default.
- W3001032298 cites W2105908213 @default.
- W3001032298 cites W2132108078 @default.
- W3001032298 cites W2136204083 @default.
- W3001032298 cites W2136587148 @default.
- W3001032298 cites W2154438850 @default.
- W3001032298 cites W2155070090 @default.
- W3001032298 cites W2155074770 @default.
- W3001032298 cites W2157868924 @default.
- W3001032298 cites W2166558648 @default.
- W3001032298 cites W2168934316 @default.
- W3001032298 cites W2172065967 @default.
- W3001032298 cites W2176314897 @default.
- W3001032298 cites W2259706127 @default.
- W3001032298 cites W2313029573 @default.
- W3001032298 cites W2320583708 @default.
- W3001032298 cites W2327720621 @default.
- W3001032298 cites W2330235342 @default.
- W3001032298 cites W2587958845 @default.
- W3001032298 cites W2736495157 @default.
- W3001032298 cites W2794182007 @default.
- W3001032298 cites W2800240522 @default.
- W3001032298 cites W2889299486 @default.
- W3001032298 cites W2904185250 @default.
- W3001032298 cites W2906332072 @default.
- W3001032298 cites W2908850744 @default.
- W3001032298 doi "https://doi.org/10.1155/2020/2192709" @default.
- W3001032298 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7204327" @default.
- W3001032298 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32411342" @default.
- W3001032298 hasPublicationYear "2020" @default.
- W3001032298 type Work @default.
- W3001032298 sameAs 3001032298 @default.
- W3001032298 citedByCount "8" @default.
- W3001032298 countsByYear W30010322982021 @default.
- W3001032298 countsByYear W30010322982022 @default.
- W3001032298 countsByYear W30010322982023 @default.
- W3001032298 crossrefType "journal-article" @default.
- W3001032298 hasAuthorship W3001032298A5031651158 @default.
- W3001032298 hasAuthorship W3001032298A5039858148 @default.
- W3001032298 hasAuthorship W3001032298A5040082618 @default.
- W3001032298 hasAuthorship W3001032298A5067912188 @default.
- W3001032298 hasAuthorship W3001032298A5077447377 @default.
- W3001032298 hasAuthorship W3001032298A5087465928 @default.
- W3001032298 hasAuthorship W3001032298A5089914269 @default.
- W3001032298 hasBestOaLocation W30010322981 @default.
- W3001032298 hasConcept C141071460 @default.
- W3001032298 hasConcept C17624336 @default.
- W3001032298 hasConcept C187212893 @default.
- W3001032298 hasConcept C188816634 @default.
- W3001032298 hasConcept C2777094939 @default.
- W3001032298 hasConcept C2778376644 @default.
- W3001032298 hasConcept C2778871575 @default.
- W3001032298 hasConcept C2779234561 @default.
- W3001032298 hasConcept C2779252433 @default.
- W3001032298 hasConcept C2908647359 @default.
- W3001032298 hasConcept C54355233 @default.
- W3001032298 hasConcept C71924100 @default.
- W3001032298 hasConcept C86803240 @default.
- W3001032298 hasConcept C99454951 @default.
- W3001032298 hasConceptScore W3001032298C141071460 @default.
- W3001032298 hasConceptScore W3001032298C17624336 @default.
- W3001032298 hasConceptScore W3001032298C187212893 @default.
- W3001032298 hasConceptScore W3001032298C188816634 @default.
- W3001032298 hasConceptScore W3001032298C2777094939 @default.
- W3001032298 hasConceptScore W3001032298C2778376644 @default.
- W3001032298 hasConceptScore W3001032298C2778871575 @default.
- W3001032298 hasConceptScore W3001032298C2779234561 @default.
- W3001032298 hasConceptScore W3001032298C2779252433 @default.
- W3001032298 hasConceptScore W3001032298C2908647359 @default.
- W3001032298 hasConceptScore W3001032298C54355233 @default.
- W3001032298 hasConceptScore W3001032298C71924100 @default.
- W3001032298 hasConceptScore W3001032298C86803240 @default.
- W3001032298 hasConceptScore W3001032298C99454951 @default.
- W3001032298 hasLocation W30010322981 @default.
- W3001032298 hasLocation W30010322982 @default.
- W3001032298 hasLocation W30010322983 @default.