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- W3001037538 abstract "All over the world, the prevalence of diabetes mellitus is increasing. The main goal of this experiment was to identify the most effective fraction of aqueous-methanol extract of Curcuma amada rhizome for its antidiabetic and antioxidative properties. The fractions (n-hexane or chloroform or ethyl-acetate or n-butanol) of aqueous-methanol extract were administered to the streptozotocin-induced diabetic groups at a dose of 10 mg/100 g body weight/day for 4 weeks. The antidiabetic and antioxidative efficacies of the fractions on glycemic, enzymatic, genomic, and histological sensors and pancreatic β-cells population and general toxicity were assessed. After the fraction treatment, out of the fraction used, the significant recovery in most sensors was noted at the ethyl-acetate fraction in glycemic, enzymatic, genomic, β cells population, diameter of the pancreatic islet and toxicity level. In conclusion, it may be stated that the ethyl-acetate fraction of C. amada was the most effective solvent in this study. Practical applications The ethyl-acetate fraction of aqueous-methanol extract of Curcuma amada has antidiabetic property, it gives a clue to the herbal medicine manufacturing company to produce phytotherapeutic drugs to cure the complication related to diabetes." @default.
- W3001037538 created "2020-01-30" @default.
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- W3001037538 date "2020-01-22" @default.
- W3001037538 modified "2023-10-18" @default.
- W3001037538 title "Antidiabetic and antioxidative efficacy of the constituents present in the fraction solvents of <i>Curcuma amada</i> rhizomes: An experimental study on the diabetic rat model" @default.
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- W3001037538 doi "https://doi.org/10.1111/jfbc.13154" @default.
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