FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3001136035> ?p ?o ?g. }

• W3001136035 endingPage "484" @default.
• W3001136035 startingPage "473" @default.
• W3001136035 abstract "Abstract Objective: The Menopause Strategies: Finding Lasting Answers for Symptoms and Health clinical trials network was funded by the National Institutes of Health to find new ways to alleviate the most common, bothersome menopausal symptoms by designing and conducting multiple concurrent clinical intervention studies, accommodating a wide scope of populations and intervention strategies. Methods: Trials were conducted in Boston, Indianapolis, Minneapolis, Oakland, Philadelphia, and Seattle, with the Data Coordinating Center in Seattle, and were designed with standardized eligibility criteria and endpoints. Primary outcomes focused on vasomotor symptoms, sleep quality and insomnia symptoms, and vaginal symptoms. Secondary outcomes included quality of life, sexual function, and mood. Results: We completed five randomized clinical trials and three ancillary studies, testing nine interventions in over 1,300 women and collecting nearly 16,000 bio-specimens. Escitalopram, venlafaxine hydrochloride extended release, and low-dose estradiol diminished hot flashes by approximately 50% as compared with a 30% decrease by placebo. No benefits on vasomotor symptoms were observed with yoga or exercise compared with usual activity, nor with omega-3 supplementation compared with placebo. Cognitive behavioral therapy for insomnia reduced self-reported insomnia symptoms and improved overall sleep quality compared with menopause education control. We did not find significant benefit from a vaginal estradiol tablet or a vaginal moisturizer compared with placebo tablet and gel in diminishing the severity of vaginal symptoms. Conclusions: The MsFLASH trials contributed substantially to our understanding of bothersome menopausal symptom treatment. It is important that clinicians counseling women about available treatment options consider all therapies—both nonhormonal and hormonal." @default.
• W3001136035 created "2020-01-30" @default.
• W3001136035 creator A5009986689 @default.
• W3001136035 creator A5040793701 @default.
• W3001136035 creator A5041374470 @default.
• W3001136035 creator A5043180253 @default.
• W3001136035 creator A5043491217 @default.
• W3001136035 creator A5047598978 @default.
• W3001136035 creator A5048654505 @default.
• W3001136035 creator A5049708025 @default.
• W3001136035 creator A5064943043 @default.
• W3001136035 creator A5068827984 @default.
• W3001136035 creator A5076423165 @default.
• W3001136035 creator A5076719936 @default.
• W3001136035 creator A5082355243 @default.
• W3001136035 creator A5082578863 @default.
• W3001136035 creator A5083313514 @default.
• W3001136035 creator A5086632845 @default.
• W3001136035 date "2020-04-01" @default.
• W3001136035 modified "2023-10-02" @default.
• W3001136035 title "Lights on MsFLASH: a review of contributions" @default.
• W3001136035 cites W103787728 @default.
• W3001136035 cites W1191391022 @default.
• W3001136035 cites W1857827700 @default.
• W3001136035 cites W1867278424 @default.
• W3001136035 cites W1965801709 @default.
• W3001136035 cites W1968040003 @default.
• W3001136035 cites W1972115463 @default.
• W3001136035 cites W1992464037 @default.
• W3001136035 cites W1993565031 @default.
• W3001136035 cites W1998829704 @default.
• W3001136035 cites W2018940119 @default.
• W3001136035 cites W2021397466 @default.
• W3001136035 cites W2030585597 @default.
• W3001136035 cites W2034156707 @default.
• W3001136035 cites W2036203679 @default.
• W3001136035 cites W2038959056 @default.
• W3001136035 cites W2045555035 @default.
• W3001136035 cites W2061642929 @default.
• W3001136035 cites W2065520705 @default.
• W3001136035 cites W2069963914 @default.
• W3001136035 cites W2070459784 @default.
• W3001136035 cites W2070506018 @default.
• W3001136035 cites W2076467455 @default.
• W3001136035 cites W2083737455 @default.
• W3001136035 cites W2100392631 @default.
• W3001136035 cites W2101409995 @default.
• W3001136035 cites W2117075389 @default.
• W3001136035 cites W2133928783 @default.
• W3001136035 cites W2136137449 @default.
• W3001136035 cites W2140449138 @default.
• W3001136035 cites W2143999957 @default.
• W3001136035 cites W2165016785 @default.
• W3001136035 cites W2165209419 @default.
• W3001136035 cites W2167000872 @default.
• W3001136035 cites W2171466849 @default.
• W3001136035 cites W2198942734 @default.
• W3001136035 cites W2208180075 @default.
• W3001136035 cites W2256490276 @default.
• W3001136035 cites W2268195027 @default.
• W3001136035 cites W2285320771 @default.
• W3001136035 cites W2292717933 @default.
• W3001136035 cites W2294424219 @default.
• W3001136035 cites W2395556627 @default.
• W3001136035 cites W2397641535 @default.
• W3001136035 cites W2399783751 @default.
• W3001136035 cites W2486478733 @default.
• W3001136035 cites W2529554855 @default.
• W3001136035 cites W2560759083 @default.
• W3001136035 cites W2604269555 @default.
• W3001136035 cites W2647715950 @default.
• W3001136035 cites W2742814779 @default.
• W3001136035 cites W2747861025 @default.
• W3001136035 cites W2769889930 @default.
• W3001136035 cites W2773188926 @default.
• W3001136035 cites W2794301989 @default.
• W3001136035 cites W2802382331 @default.
• W3001136035 cites W2940806507 @default.
• W3001136035 cites W2944429941 @default.
• W3001136035 cites W2993539607 @default.
• W3001136035 cites W4242045296 @default.
• W3001136035 cites W4255045039 @default.
• W3001136035 doi "https://doi.org/10.1097/gme.0000000000001461" @default.
• W3001136035 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8009305" @default.
• W3001136035 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31977667" @default.
• W3001136035 hasPublicationYear "2020" @default.
• W3001136035 type Work @default.
• W3001136035 sameAs 3001136035 @default.
• W3001136035 citedByCount "13" @default.
• W3001136035 countsByYear W30011360352020 @default.
• W3001136035 countsByYear W30011360352021 @default.
• W3001136035 countsByYear W30011360352022 @default.
• W3001136035 countsByYear W30011360352023 @default.
• W3001136035 crossrefType "journal-article" @default.
• W3001136035 hasAuthorship W3001136035A5009986689 @default.
• W3001136035 hasAuthorship W3001136035A5040793701 @default.
• W3001136035 hasAuthorship W3001136035A5041374470 @default.
• W3001136035 hasAuthorship W3001136035A5043180253 @default.

• next