FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3001161114> ?p ?o ?g. }

• W3001161114 abstract "The methylenetetrahydrofolate reductase (MTHFR) may play a pathological role in polycystic ovary syndrome (PCOS). However, the conclusions of published reports on the relationship between the MTHFR C677T polymorphism and PCOS risk remain controversial.To derive a more precise estimation we performed a metaanalysis based on 22 studies that together included 2405 cases and 2419 controls. PubMed, EMBASE, WanFang and the Chinese National Knowledge Infrastructure databases were used to retrieve articles up to up to October 28, 2019. The crude odds ratios (ORs) with 95% confidence intervals (95% CI) were calculated to evaluate the association.Metaanalysis results showed a significant association between the MTHFR C677T polymorphism and PCOS risk in 3 genetic models (allele model: OR = 1.40, 95% CI = 1.27-1.53; dominant model: OR = 1.47, 95% CI = 1.17-1.85); homozygous model: OR = 1.90, 95% CI = 1.55-2.32). Moreover, significant associations were observed when stratified by ethnicity, source of controls, etiology, and genotype methods.This metaanalysis suggests that the T-allele of the MTHFR C677T polymorphism is associated with an increased risk of PCOS, especially in Asians further studies with larger population sizes are needed to confirm these results." @default.
• W3001161114 created "2020-01-30" @default.
• W3001161114 creator A5007951793 @default.
• W3001161114 creator A5009437296 @default.
• W3001161114 creator A5047943765 @default.
• W3001161114 creator A5061537073 @default.
• W3001161114 creator A5072835032 @default.
• W3001161114 creator A5083532124 @default.
• W3001161114 creator A5034841940 @default.
• W3001161114 date "2020-01-01" @default.
• W3001161114 modified "2023-09-23" @default.
• W3001161114 title "Significant association between methylenetetrahydrofolate reductase gene C677T polymorphism with polycystic ovary syndrome risk" @default.
• W3001161114 cites W1544987908 @default.
• W3001161114 cites W1966292733 @default.
• W3001161114 cites W1974630582 @default.
• W3001161114 cites W1988738961 @default.
• W3001161114 cites W1993610708 @default.
• W3001161114 cites W2002146355 @default.
• W3001161114 cites W2018541384 @default.
• W3001161114 cites W2020023968 @default.
• W3001161114 cites W2024109963 @default.
• W3001161114 cites W2025780799 @default.
• W3001161114 cites W2042608716 @default.
• W3001161114 cites W2050026469 @default.
• W3001161114 cites W2069754993 @default.
• W3001161114 cites W2074056530 @default.
• W3001161114 cites W2086101287 @default.
• W3001161114 cites W2107328434 @default.
• W3001161114 cites W2108067228 @default.
• W3001161114 cites W2116701818 @default.
• W3001161114 cites W2119378963 @default.
• W3001161114 cites W2125435699 @default.
• W3001161114 cites W2144393300 @default.
• W3001161114 cites W2147127250 @default.
• W3001161114 cites W2150000105 @default.
• W3001161114 cites W2155744347 @default.
• W3001161114 cites W2157515962 @default.
• W3001161114 cites W2163396925 @default.
• W3001161114 cites W2171650440 @default.
• W3001161114 cites W2299181839 @default.
• W3001161114 cites W2419123044 @default.
• W3001161114 cites W2473580390 @default.
• W3001161114 cites W2502759604 @default.
• W3001161114 cites W2509848527 @default.
• W3001161114 cites W2575959739 @default.
• W3001161114 cites W2667664752 @default.
• W3001161114 cites W2889455179 @default.
• W3001161114 cites W2980726202 @default.
• W3001161114 doi "https://doi.org/10.1097/md.0000000000018720" @default.
• W3001161114 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7004748" @default.
• W3001161114 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31977861" @default.
• W3001161114 hasPublicationYear "2020" @default.
• W3001161114 type Work @default.
• W3001161114 sameAs 3001161114 @default.
• W3001161114 citedByCount "2" @default.
• W3001161114 countsByYear W30011611142020 @default.
• W3001161114 countsByYear W30011611142021 @default.
• W3001161114 crossrefType "journal-article" @default.
• W3001161114 hasAuthorship W3001161114A5007951793 @default.
• W3001161114 hasAuthorship W3001161114A5009437296 @default.
• W3001161114 hasAuthorship W3001161114A5034841940 @default.
• W3001161114 hasAuthorship W3001161114A5047943765 @default.
• W3001161114 hasAuthorship W3001161114A5061537073 @default.
• W3001161114 hasAuthorship W3001161114A5072835032 @default.
• W3001161114 hasAuthorship W3001161114A5083532124 @default.
• W3001161114 hasBestOaLocation W30011611141 @default.
• W3001161114 hasConcept C104317684 @default.
• W3001161114 hasConcept C126322002 @default.
• W3001161114 hasConcept C135763542 @default.
• W3001161114 hasConcept C143998085 @default.
• W3001161114 hasConcept C156957248 @default.
• W3001161114 hasConcept C180754005 @default.
• W3001161114 hasConcept C2777391703 @default.
• W3001161114 hasConcept C29456083 @default.
• W3001161114 hasConcept C2992519594 @default.
• W3001161114 hasConcept C3018442814 @default.
• W3001161114 hasConcept C43563269 @default.
• W3001161114 hasConcept C44249647 @default.
• W3001161114 hasConcept C511355011 @default.
• W3001161114 hasConcept C54355233 @default.
• W3001161114 hasConcept C60644358 @default.
• W3001161114 hasConcept C71924100 @default.
• W3001161114 hasConcept C86803240 @default.
• W3001161114 hasConcept C90924648 @default.
• W3001161114 hasConcept C95190672 @default.
• W3001161114 hasConceptScore W3001161114C104317684 @default.
• W3001161114 hasConceptScore W3001161114C126322002 @default.
• W3001161114 hasConceptScore W3001161114C135763542 @default.
• W3001161114 hasConceptScore W3001161114C143998085 @default.
• W3001161114 hasConceptScore W3001161114C156957248 @default.
• W3001161114 hasConceptScore W3001161114C180754005 @default.
• W3001161114 hasConceptScore W3001161114C2777391703 @default.
• W3001161114 hasConceptScore W3001161114C29456083 @default.
• W3001161114 hasConceptScore W3001161114C2992519594 @default.
• W3001161114 hasConceptScore W3001161114C3018442814 @default.
• W3001161114 hasConceptScore W3001161114C43563269 @default.
• W3001161114 hasConceptScore W3001161114C44249647 @default.
• W3001161114 hasConceptScore W3001161114C511355011 @default.
• W3001161114 hasConceptScore W3001161114C54355233 @default.
• W3001161114 hasConceptScore W3001161114C60644358 @default.

• next