FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3001429076> ?p ?o ?g. }

• W3001429076 endingPage "801" @default.
• W3001429076 startingPage "801" @default.
• W3001429076 abstract "Partial oxidation of polyvinyl alcohol (PVA) with potassium permanganate turned out to be an efficient method to fabricate smart scaffolds for tissue engineering, endowed with biodegradation and protein delivery capacity. This work considered for the first time the use of halogens (bromine, chlorine and iodine) as less aggressive agents than potassium permanganate to perform controlled PVA oxidation, in order to prevent degradation of polymer molecular size upon chemical modification. Oxidized PVA solutions were chemically characterized (i.e., dinitrophenylhydrazine assay, viscosity measurements, molecular size distribution) before preparing physically cross-linked hydrogels. Scaffolds were assessed for their mechanical properties and cell/tissue biocompatibiliy through cytotoxic extract test on IMR-90 fibroblasts and subcutaneous implantation into BALB/c mice. According to chemical investigations, bromine and iodine allowed for minor alteration of polymer molecular weight. Uniaxial tensile tests demonstrated that oxidized scaffolds had decreased mechanical resistance to deformation, suggesting tunable hydrogel stiffness. Finally, oxidized hydrogels exhibited high biocompatibility both in vitro and in vivo, resulting neither to be cytotoxic nor to elicit severe immunitary host reaction in comparison with atoxic PVA. In conclusion, PVA hydrogels oxidized by halogens were successfully fabricated in the effort of adapting polymer characteristics to specific tissue engineering applications." @default.
• W3001429076 created "2020-01-30" @default.
• W3001429076 creator A5000666523 @default.
• W3001429076 creator A5010380702 @default.
• W3001429076 creator A5013783191 @default.
• W3001429076 creator A5018896366 @default.
• W3001429076 creator A5027463490 @default.
• W3001429076 creator A5034239187 @default.
• W3001429076 creator A5043808387 @default.
• W3001429076 creator A5049701385 @default.
• W3001429076 creator A5076046725 @default.
• W3001429076 creator A5086819522 @default.
• W3001429076 creator A5016725802 @default.
• W3001429076 date "2020-01-25" @default.
• W3001429076 modified "2023-10-18" @default.
• W3001429076 title "Halogen-Mediated Partial Oxidation of Polyvinyl Alcohol for Tissue Engineering Purposes" @default.
• W3001429076 cites W1423754210 @default.
• W3001429076 cites W1881615959 @default.
• W3001429076 cites W1916216790 @default.
• W3001429076 cites W1960095065 @default.
• W3001429076 cites W1996293182 @default.
• W3001429076 cites W2000270888 @default.
• W3001429076 cites W2014821900 @default.
• W3001429076 cites W2030309836 @default.
• W3001429076 cites W2034746004 @default.
• W3001429076 cites W2042823812 @default.
• W3001429076 cites W2043328440 @default.
• W3001429076 cites W2054526986 @default.
• W3001429076 cites W2055068431 @default.
• W3001429076 cites W2073021326 @default.
• W3001429076 cites W2110757989 @default.
• W3001429076 cites W2135606078 @default.
• W3001429076 cites W2150289384 @default.
• W3001429076 cites W2162007826 @default.
• W3001429076 cites W2171819806 @default.
• W3001429076 cites W2265869790 @default.
• W3001429076 cites W2345284931 @default.
• W3001429076 cites W2514907273 @default.
• W3001429076 cites W2567950703 @default.
• W3001429076 cites W2600194131 @default.
• W3001429076 cites W2617404882 @default.
• W3001429076 cites W2741955823 @default.
• W3001429076 cites W2778813663 @default.
• W3001429076 cites W2783821774 @default.
• W3001429076 cites W2794646962 @default.
• W3001429076 cites W2799305195 @default.
• W3001429076 cites W2804693185 @default.
• W3001429076 cites W2805141665 @default.
• W3001429076 cites W2810325905 @default.
• W3001429076 cites W2900467024 @default.
• W3001429076 cites W2904444744 @default.
• W3001429076 cites W2911603193 @default.
• W3001429076 cites W2951597930 @default.
• W3001429076 cites W2990468812 @default.
• W3001429076 cites W1984937429 @default.
• W3001429076 doi "https://doi.org/10.3390/ijms21030801" @default.
• W3001429076 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7038068" @default.
• W3001429076 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31991838" @default.
• W3001429076 hasPublicationYear "2020" @default.
• W3001429076 type Work @default.
• W3001429076 sameAs 3001429076 @default.
• W3001429076 citedByCount "17" @default.
• W3001429076 countsByYear W30014290762020 @default.
• W3001429076 countsByYear W30014290762021 @default.
• W3001429076 countsByYear W30014290762022 @default.
• W3001429076 countsByYear W30014290762023 @default.
• W3001429076 crossrefType "journal-article" @default.
• W3001429076 hasAuthorship W3001429076A5000666523 @default.
• W3001429076 hasAuthorship W3001429076A5010380702 @default.
• W3001429076 hasAuthorship W3001429076A5013783191 @default.
• W3001429076 hasAuthorship W3001429076A5016725802 @default.
• W3001429076 hasAuthorship W3001429076A5018896366 @default.
• W3001429076 hasAuthorship W3001429076A5027463490 @default.
• W3001429076 hasAuthorship W3001429076A5034239187 @default.
• W3001429076 hasAuthorship W3001429076A5043808387 @default.
• W3001429076 hasAuthorship W3001429076A5049701385 @default.
• W3001429076 hasAuthorship W3001429076A5076046725 @default.
• W3001429076 hasAuthorship W3001429076A5086819522 @default.
• W3001429076 hasBestOaLocation W30014290761 @default.
• W3001429076 hasConcept C108586683 @default.
• W3001429076 hasConcept C127413603 @default.
• W3001429076 hasConcept C136229726 @default.
• W3001429076 hasConcept C178790620 @default.
• W3001429076 hasConcept C185592680 @default.
• W3001429076 hasConcept C188027245 @default.
• W3001429076 hasConcept C2775885272 @default.
• W3001429076 hasConcept C2777230088 @default.
• W3001429076 hasConcept C2778551929 @default.
• W3001429076 hasConcept C2780666587 @default.
• W3001429076 hasConcept C42360764 @default.
• W3001429076 hasConcept C49892992 @default.
• W3001429076 hasConcept C505241676 @default.
• W3001429076 hasConcept C517835270 @default.
• W3001429076 hasConcept C521977710 @default.
• W3001429076 hasConcept C539932907 @default.
• W3001429076 hasConcept C71924100 @default.
• W3001429076 hasConceptScore W3001429076C108586683 @default.
• W3001429076 hasConceptScore W3001429076C127413603 @default.

• next