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- W3001867141 abstract "Furosemide is a drug that has not only a renal effect, but also a vascular one, resulting in decreased left atrial and ventricularfilling pressure accompanied by an increase in venous compliance, all of this with significant effects on central cardiac hemodynamics.In dialysis patients, it is still unclear the efficiency of furosemide, a diuretic drug that inhibits the Na+, K+, 2CL� cotransporter in the renal tubular system. Also, furosemide need to be used at much higher doses because of its pharmacokinetic changes in the context of impaired renal clearance.The aim of our study was to investigate whether furosemide induces changes in cardiovascular hemodynamics in end-stage renal disease (ESRD) patients, using standard echocardiography and Tissue Doppler Imaging (TDI).We foundcorrelations between furosemide useand improved cardiac parameters, assessed by multiple echocardiographic variables, and we consider that furosemide has complementary effects in dialysis patients with residual diuresis." @default.
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- W3001867141 date "2019-04-15" @default.
- W3001867141 modified "2023-09-25" @default.
- W3001867141 title "Furosemide Pharmacodynamics and Cardiovascular Effects in Hemodialysis Patients" @default.
- W3001867141 doi "https://doi.org/10.37358/rc.19.3.7042" @default.
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