Matches in SemOpenAlex for { <https://semopenalex.org/work/W3002170199> ?p ?o ?g. }
- W3002170199 endingPage "887" @default.
- W3002170199 startingPage "876" @default.
- W3002170199 abstract "Although calcium sulfate bone cements possess favorable characteristics of excellent clinical handling and osteoconductivity, the rapid degradation and poor bioactivity limit their wide applications. This study reports a type of novel injectable and self-setting composite materials for bone defect repair. Magnesium substituted tricalcium phosphate nanoparticles (43.8±9.0 nm) and calcium sulfate hemihydrate micro-size particles (5–21 µm) were mixed with a polyvinyl alcohol solution with optimal compositions to obtain the composite materials, which showed reasonable initial setting time (11.7–19.2 min) and suitable compressed strength (2.28–6.33 MPa). By utilizing magnesium powder as a porogen, macro-pores (>100 µm) together with micro-pores were created in the final product after setting. In addition, MC3T3E1 cells extended well and exhibited numerous lamellipodia and long filopodia when cultured with the composite materials, indicating that they had no cytotoxicity. The in vivo results indicated that the injectable composite materials could achieve bone defect repair, when implanted in beagle femoral condyle defects for 10 months. Our results show that the new injectable composite materials are biocompatible and biodegradable, which possess great potential for bone defect repair." @default.
- W3002170199 created "2020-01-30" @default.
- W3002170199 creator A5001990780 @default.
- W3002170199 creator A5017957835 @default.
- W3002170199 creator A5030306448 @default.
- W3002170199 creator A5041181056 @default.
- W3002170199 creator A5041744189 @default.
- W3002170199 creator A5047417366 @default.
- W3002170199 creator A5065032339 @default.
- W3002170199 creator A5085085885 @default.
- W3002170199 date "2020-01-20" @default.
- W3002170199 modified "2023-09-23" @default.
- W3002170199 title "Novel injectable and self-setting composite materials for bone defect repair" @default.
- W3002170199 cites W1527208521 @default.
- W3002170199 cites W1941684470 @default.
- W3002170199 cites W1969303596 @default.
- W3002170199 cites W1975264644 @default.
- W3002170199 cites W1984685797 @default.
- W3002170199 cites W1995022241 @default.
- W3002170199 cites W1995605393 @default.
- W3002170199 cites W1996412580 @default.
- W3002170199 cites W1996760356 @default.
- W3002170199 cites W2011091784 @default.
- W3002170199 cites W2012655169 @default.
- W3002170199 cites W2022512619 @default.
- W3002170199 cites W2027225709 @default.
- W3002170199 cites W2051810805 @default.
- W3002170199 cites W2053877801 @default.
- W3002170199 cites W2077230011 @default.
- W3002170199 cites W2090476488 @default.
- W3002170199 cites W2090735602 @default.
- W3002170199 cites W2092791587 @default.
- W3002170199 cites W2113613856 @default.
- W3002170199 cites W2114002624 @default.
- W3002170199 cites W2136652158 @default.
- W3002170199 cites W2142057495 @default.
- W3002170199 cites W2157731550 @default.
- W3002170199 cites W2159210886 @default.
- W3002170199 cites W2350780690 @default.
- W3002170199 cites W245194097 @default.
- W3002170199 cites W2590198524 @default.
- W3002170199 cites W2609238255 @default.
- W3002170199 cites W2612516430 @default.
- W3002170199 cites W2742698850 @default.
- W3002170199 cites W2752700089 @default.
- W3002170199 cites W2790246139 @default.
- W3002170199 cites W2790515784 @default.
- W3002170199 cites W2791851726 @default.
- W3002170199 cites W2915965441 @default.
- W3002170199 cites W2924861592 @default.
- W3002170199 cites W2949316410 @default.
- W3002170199 cites W2967698556 @default.
- W3002170199 doi "https://doi.org/10.1007/s40843-019-1233-7" @default.
- W3002170199 hasPublicationYear "2020" @default.
- W3002170199 type Work @default.
- W3002170199 sameAs 3002170199 @default.
- W3002170199 citedByCount "11" @default.
- W3002170199 countsByYear W30021701992020 @default.
- W3002170199 countsByYear W30021701992021 @default.
- W3002170199 countsByYear W30021701992022 @default.
- W3002170199 countsByYear W30021701992023 @default.
- W3002170199 crossrefType "journal-article" @default.
- W3002170199 hasAuthorship W3002170199A5001990780 @default.
- W3002170199 hasAuthorship W3002170199A5017957835 @default.
- W3002170199 hasAuthorship W3002170199A5030306448 @default.
- W3002170199 hasAuthorship W3002170199A5041181056 @default.
- W3002170199 hasAuthorship W3002170199A5041744189 @default.
- W3002170199 hasAuthorship W3002170199A5047417366 @default.
- W3002170199 hasAuthorship W3002170199A5065032339 @default.
- W3002170199 hasAuthorship W3002170199A5085085885 @default.
- W3002170199 hasBestOaLocation W30021701991 @default.
- W3002170199 hasConcept C104779481 @default.
- W3002170199 hasConcept C127413603 @default.
- W3002170199 hasConcept C1318750 @default.
- W3002170199 hasConcept C136229726 @default.
- W3002170199 hasConcept C159985019 @default.
- W3002170199 hasConcept C191897082 @default.
- W3002170199 hasConcept C192562407 @default.
- W3002170199 hasConcept C2778551929 @default.
- W3002170199 hasConcept C42360764 @default.
- W3002170199 hasConcept C519063684 @default.
- W3002170199 hasConcept C71924100 @default.
- W3002170199 hasConceptScore W3002170199C104779481 @default.
- W3002170199 hasConceptScore W3002170199C127413603 @default.
- W3002170199 hasConceptScore W3002170199C1318750 @default.
- W3002170199 hasConceptScore W3002170199C136229726 @default.
- W3002170199 hasConceptScore W3002170199C159985019 @default.
- W3002170199 hasConceptScore W3002170199C191897082 @default.
- W3002170199 hasConceptScore W3002170199C192562407 @default.
- W3002170199 hasConceptScore W3002170199C2778551929 @default.
- W3002170199 hasConceptScore W3002170199C42360764 @default.
- W3002170199 hasConceptScore W3002170199C519063684 @default.
- W3002170199 hasConceptScore W3002170199C71924100 @default.
- W3002170199 hasIssue "5" @default.
- W3002170199 hasLocation W30021701991 @default.
- W3002170199 hasOpenAccess W3002170199 @default.
- W3002170199 hasPrimaryLocation W30021701991 @default.
- W3002170199 hasRelatedWork W2005496670 @default.