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• W3002183889 abstract "Early-childhood caries is one of the most prevalent diseases in children worldwide and, while preventable, remains a global public health concern. Untreated cavities are painful and expensive and can lead to tooth loss and a lower quality of life. Caries are driven by acid production via microbial fermentation of dietary carbohydrates, resulting in enamel erosion. While caries is a well-studied disease, most research has focused on bacterial impacts, even though fungi are commensal organisms living within the plaque biofilm. There is very little known about how fungi impact caries pathogenicity. The elucidation of fungal taxa involved in caries disease progression is necessary for a more holistic view of the human oral microbiome. Data from this study will improve our understanding of how the fungal community changes as disease progresses and provide insight into the complex etiology of dental caries, which is necessary for the development of treatment plans and preventative measures." @default.
• W3002183889 created "2020-01-30" @default.
• W3002183889 creator A5019321656 @default.
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• W3002183889 date "2020-03-18" @default.
• W3002183889 modified "2023-09-25" @default.
• W3002183889 title "Site-Specific Profiling of the Dental Mycobiome Reveals Strong Taxonomic Shifts during Progression of Early-Childhood Caries" @default.
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• W3002183889 doi "https://doi.org/10.1128/aem.02825-19" @default.
• W3002183889 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7082576" @default.
• W3002183889 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31953340" @default.
• W3002183889 hasPublicationYear "2020" @default.
• W3002183889 type Work @default.
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