Matches in SemOpenAlex for { <https://semopenalex.org/work/W3002207652> ?p ?o ?g. }
- W3002207652 endingPage "e18732" @default.
- W3002207652 startingPage "e18732" @default.
- W3002207652 abstract "The aim of the study reported here was to evaluate the feasibility and safety of raltitrexed and nedaplatin with concurrent radiotherapy in patients with unresectable, locally advanced esophageal squamous cell carcinoma (ESCC).Eligible patients were adults with newly diagnosed untreated, unresectable esophageal cancer in stages I to IV with lymph node metastases or cervical esophageal cancer. Patients received nedaplatin 25 mg/m per day on day 1-3, raltitrexed 3 mg/m on days 1 repeated every 21 days for 2 cycles, and combined concurrent radiotherapy (2 Gy/fraction, total dose of 60 Gy).Thirty patients were included with squamous cell carcinoma. The median follow-up duration was 24 months. The overall response rate was 90%. The 1-year and 2-year overall survival rates for all patients were 70.4% and 55.7% with a median survival time of 30 months, and the median progression free survival was 20 month. The major toxicities were leukopenia and thrombopenia, with grade 3 to 4 leukopenia and thrombopenia were 50% and 30% of patients.Concurrent chemoradiotherapy with raltitrexed and nedaplatin agents frequently caused myelosuppression but was highly active and suggested to be a promising treatment option for locally advanced ESCC." @default.
- W3002207652 created "2020-01-30" @default.
- W3002207652 creator A5012677271 @default.
- W3002207652 creator A5033811167 @default.
- W3002207652 creator A5056324513 @default.
- W3002207652 creator A5065058975 @default.
- W3002207652 creator A5069600772 @default.
- W3002207652 creator A5071442998 @default.
- W3002207652 creator A5072855352 @default.
- W3002207652 creator A5074140059 @default.
- W3002207652 creator A5074175188 @default.
- W3002207652 creator A5081374377 @default.
- W3002207652 creator A5083922270 @default.
- W3002207652 date "2020-01-01" @default.
- W3002207652 modified "2023-09-27" @default.
- W3002207652 title "Concurrent chemoradiotherapy with raltitrexed and nedaplatin regimen for esophageal squamous cell carcinoma" @default.
- W3002207652 cites W1846590026 @default.
- W3002207652 cites W1968626722 @default.
- W3002207652 cites W1999726239 @default.
- W3002207652 cites W2008190193 @default.
- W3002207652 cites W2008575122 @default.
- W3002207652 cites W2018187578 @default.
- W3002207652 cites W2019607817 @default.
- W3002207652 cites W2026908054 @default.
- W3002207652 cites W2033451764 @default.
- W3002207652 cites W2037231595 @default.
- W3002207652 cites W2088175510 @default.
- W3002207652 cites W2092925950 @default.
- W3002207652 cites W2099918668 @default.
- W3002207652 cites W2117223681 @default.
- W3002207652 cites W2121976791 @default.
- W3002207652 cites W2127356591 @default.
- W3002207652 cites W2136571540 @default.
- W3002207652 cites W2144263975 @default.
- W3002207652 cites W2146269511 @default.
- W3002207652 cites W2153660276 @default.
- W3002207652 cites W2167717055 @default.
- W3002207652 cites W2221837786 @default.
- W3002207652 cites W2317192938 @default.
- W3002207652 cites W2324592094 @default.
- W3002207652 cites W2373543256 @default.
- W3002207652 cites W2552639339 @default.
- W3002207652 cites W2885831706 @default.
- W3002207652 cites W2893399598 @default.
- W3002207652 cites W2896585861 @default.
- W3002207652 cites W2943324538 @default.
- W3002207652 cites W2972064652 @default.
- W3002207652 cites W4236554935 @default.
- W3002207652 cites W611226111 @default.
- W3002207652 cites W2160251780 @default.
- W3002207652 doi "https://doi.org/10.1097/md.0000000000018732" @default.
- W3002207652 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7004679" @default.
- W3002207652 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31977864" @default.
- W3002207652 hasPublicationYear "2020" @default.
- W3002207652 type Work @default.
- W3002207652 sameAs 3002207652 @default.
- W3002207652 citedByCount "3" @default.
- W3002207652 countsByYear W30022076522020 @default.
- W3002207652 countsByYear W30022076522022 @default.
- W3002207652 countsByYear W30022076522023 @default.
- W3002207652 crossrefType "journal-article" @default.
- W3002207652 hasAuthorship W3002207652A5012677271 @default.
- W3002207652 hasAuthorship W3002207652A5033811167 @default.
- W3002207652 hasAuthorship W3002207652A5056324513 @default.
- W3002207652 hasAuthorship W3002207652A5065058975 @default.
- W3002207652 hasAuthorship W3002207652A5069600772 @default.
- W3002207652 hasAuthorship W3002207652A5071442998 @default.
- W3002207652 hasAuthorship W3002207652A5072855352 @default.
- W3002207652 hasAuthorship W3002207652A5074140059 @default.
- W3002207652 hasAuthorship W3002207652A5074175188 @default.
- W3002207652 hasAuthorship W3002207652A5081374377 @default.
- W3002207652 hasAuthorship W3002207652A5083922270 @default.
- W3002207652 hasBestOaLocation W30022076521 @default.
- W3002207652 hasConcept C121608353 @default.
- W3002207652 hasConcept C123321153 @default.
- W3002207652 hasConcept C126322002 @default.
- W3002207652 hasConcept C141071460 @default.
- W3002207652 hasConcept C143998085 @default.
- W3002207652 hasConcept C2776694085 @default.
- W3002207652 hasConcept C2778203143 @default.
- W3002207652 hasConcept C2778239845 @default.
- W3002207652 hasConcept C2778424827 @default.
- W3002207652 hasConcept C2779268555 @default.
- W3002207652 hasConcept C2779742542 @default.
- W3002207652 hasConcept C2780456651 @default.
- W3002207652 hasConcept C2780873365 @default.
- W3002207652 hasConcept C2781413609 @default.
- W3002207652 hasConcept C509974204 @default.
- W3002207652 hasConcept C71924100 @default.
- W3002207652 hasConcept C90924648 @default.
- W3002207652 hasConceptScore W3002207652C121608353 @default.
- W3002207652 hasConceptScore W3002207652C123321153 @default.
- W3002207652 hasConceptScore W3002207652C126322002 @default.
- W3002207652 hasConceptScore W3002207652C141071460 @default.
- W3002207652 hasConceptScore W3002207652C143998085 @default.
- W3002207652 hasConceptScore W3002207652C2776694085 @default.
- W3002207652 hasConceptScore W3002207652C2778203143 @default.
- W3002207652 hasConceptScore W3002207652C2778239845 @default.