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• W3002363216 abstract "BACKGROUND Previous studies have shown that hyperbaric oxygen therapy (HBOT) can improve the motor functions and memory of post-stroke patients in the chronic stage. OBJECTIVE The aim of this study is to evaluate the effects of HBOT on overall cognitive functions of post-stroke patients in the chronic stage. The nature, type and location of the stroke were investigated as possible modifiers. METHODS A retrospective analysis was conducted on patients who were treated with HBOT for chronic stroke (>3 months) between 2008-2018. Participants were treated in a multi-place hyperbaric chamber with the following protocols: 40 to 60 daily sessions, 5 days per week, each session included 90 min of 100% oxygen at 2 ATA with 5 min air brakes every 20 minutes. Clinically significant improvements (CSI) were defined as > 0.5 standard deviation (SD). RESULTS The study included 162 patients (75.3% males) with a mean age of 60.75±12.91. Of them, 77(47.53%) had cortical strokes, 87(53.7%) strokes were located in the left hemisphere and 121 suffered ischemic strokes (74.6%).HBOT induced a significant increase in all the cognitive function domains (p   0.05). Hemorrhagic strokes had a significantly higher improvement in information processing speed post-HBOT (p < 0.05). Left hemisphere strokes had a higher increase in the motor domain (p < 0.05). In all cognitive domains, the baseline cognitive function was a significant predictor of CSI (p < 0.05), while stroke type, location and side were not significant predictors. CONCLUSIONS HBOT induces significant improvements in all cognitive domains even in the late chronic stage. The selection of post-stroke patients for HBOT should be based on functional analysis and baseline cognitive scores rather than the stroke type, location or side of lesion." @default.
• W3002363216 created "2020-01-30" @default.
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• W3002363216 date "2020-02-11" @default.
• W3002363216 modified "2023-10-03" @default.
• W3002363216 title "Hyperbaric oxygen therapy improves neurocognitive functions of post-stroke patients – a retrospective analysis" @default.
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• W3002363216 doi "https://doi.org/10.3233/rnn-190959" @default.
• W3002363216 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7081098" @default.
• W3002363216 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31985478" @default.
• W3002363216 hasPublicationYear "2020" @default.
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