FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3002937224> ?p ?o ?g. }

• W3002937224 endingPage "e287" @default.
• W3002937224 startingPage "e276" @default.
• W3002937224 abstract "BackgroundHIV self-testing increases testing uptake in sub-Saharan Africa but scale-up is challenging because of resource constraints. We evaluated an HIV self-testing intervention integrated into high-burden outpatient departments in Malawi.MethodsIn this cluster-randomised trial, we recruited participants aged 15 years or older from 15 outpatient departments at high-burden health facilities (including health centres, mission hospitals, and district hospitals) in central and southern Malawi. The trial was clustered at the health facility level. We used constrained randomisation to allocate each cluster (1:1:1) to one of the following groups: standard provider-initiated testing and counselling with no intervention (provider offered during consultations), optimised provider-initiated testing and counselling (with additional provider training and morning HIV testing), and facility-based HIV self-testing (Oraquick HIV self-test, group demonstration and distribution, and private spaces for interpretation and counselling). The primary outcome was the proportion of outpatients tested for HIV on the day of enrolment, measured through exit surveys with a sample of outpatients. Analyses were on an intention-to-treat basis. The trial is registered with ClinicalTrials.gov, NCT03271307, and Pan African Clinical Trials, PACTR201711002697316.FindingsBetween Sept 12, 2017, and Feb 23, 2018, 5885 outpatients completed an exit survey—2097 in the HIV self-testing group, 1951 in the standard provider-initiated testing and counselling group, and 1837 in the optimised provider-initiated testing and counselling group. 1063 (51%) of 2097 patients in the HIV self-testing group had HIV testing on the same day as enrolment, compared with 248 (13%) of 1951 in the standard provider-initiated testing and counselling group and 261 (14%) of 1837 in the optimised provider-initiated testing and counselling group. The odds of same-day HIV testing were significantly higher in the facility-based HIV self-testing group compared with either standard provider-initiated testing and counselling (adjusted odds ratio 8·52, 95% CI 3·98–18·24) or optimised provider-initiated testing and counselling (6·29, 2·96–13·38). Around 4% of those tested in the standard provider-initiated testing and counselling and optimised provider-initiated testing and counselling groups felt coerced to test, and around 1% felt coerced to share test results. No coercion was reported in the facility-based HIV self-testing group.InterpretationFacility-based HIV self-testing increased HIV testing among outpatients in Malawi, with a minimal risk of adverse events. Facility-based HIV self-testing should be considered for scale-up in settings with a high unmet need for HIV testing.FundingUnited States Agency for International Development. HIV self-testing increases testing uptake in sub-Saharan Africa but scale-up is challenging because of resource constraints. We evaluated an HIV self-testing intervention integrated into high-burden outpatient departments in Malawi. In this cluster-randomised trial, we recruited participants aged 15 years or older from 15 outpatient departments at high-burden health facilities (including health centres, mission hospitals, and district hospitals) in central and southern Malawi. The trial was clustered at the health facility level. We used constrained randomisation to allocate each cluster (1:1:1) to one of the following groups: standard provider-initiated testing and counselling with no intervention (provider offered during consultations), optimised provider-initiated testing and counselling (with additional provider training and morning HIV testing), and facility-based HIV self-testing (Oraquick HIV self-test, group demonstration and distribution, and private spaces for interpretation and counselling). The primary outcome was the proportion of outpatients tested for HIV on the day of enrolment, measured through exit surveys with a sample of outpatients. Analyses were on an intention-to-treat basis. The trial is registered with ClinicalTrials.gov, NCT03271307, and Pan African Clinical Trials, PACTR201711002697316. Between Sept 12, 2017, and Feb 23, 2018, 5885 outpatients completed an exit survey—2097 in the HIV self-testing group, 1951 in the standard provider-initiated testing and counselling group, and 1837 in the optimised provider-initiated testing and counselling group. 1063 (51%) of 2097 patients in the HIV self-testing group had HIV testing on the same day as enrolment, compared with 248 (13%) of 1951 in the standard provider-initiated testing and counselling group and 261 (14%) of 1837 in the optimised provider-initiated testing and counselling group. The odds of same-day HIV testing were significantly higher in the facility-based HIV self-testing group compared with either standard provider-initiated testing and counselling (adjusted odds ratio 8·52, 95% CI 3·98–18·24) or optimised provider-initiated testing and counselling (6·29, 2·96–13·38). Around 4% of those tested in the standard provider-initiated testing and counselling and optimised provider-initiated testing and counselling groups felt coerced to test, and around 1% felt coerced to share test results. No coercion was reported in the facility-based HIV self-testing group. Facility-based HIV self-testing increased HIV testing among outpatients in Malawi, with a minimal risk of adverse events. Facility-based HIV self-testing should be considered for scale-up in settings with a high unmet need for HIV testing." @default.
• W3002937224 created "2020-01-30" @default.
• W3002937224 creator A5012893141 @default.
• W3002937224 creator A5019417569 @default.
• W3002937224 creator A5020754367 @default.
• W3002937224 creator A5025427376 @default.
• W3002937224 creator A5032216924 @default.
• W3002937224 creator A5044132777 @default.
• W3002937224 creator A5045907837 @default.
• W3002937224 creator A5047394439 @default.
• W3002937224 creator A5048283582 @default.
• W3002937224 creator A5049400743 @default.
• W3002937224 creator A5051590038 @default.
• W3002937224 creator A5051728760 @default.
• W3002937224 creator A5055483615 @default.
• W3002937224 creator A5090243534 @default.
• W3002937224 creator A5091815735 @default.
• W3002937224 date "2020-02-01" @default.
• W3002937224 modified "2023-10-15" @default.
• W3002937224 title "Effect of facility-based HIV self-testing on uptake of testing among outpatients in Malawi: a cluster-randomised trial" @default.
• W3002937224 cites W1811824508 @default.
• W3002937224 cites W1983018462 @default.
• W3002937224 cites W2034816881 @default.
• W3002937224 cites W2065099417 @default.
• W3002937224 cites W2067889049 @default.
• W3002937224 cites W2094486936 @default.
• W3002937224 cites W2146829799 @default.
• W3002937224 cites W2150491926 @default.
• W3002937224 cites W2293073501 @default.
• W3002937224 cites W2517017528 @default.
• W3002937224 cites W2556949014 @default.
• W3002937224 cites W2592868996 @default.
• W3002937224 cites W2594460901 @default.
• W3002937224 cites W2605505068 @default.
• W3002937224 cites W2766107086 @default.
• W3002937224 cites W2769247552 @default.
• W3002937224 cites W2891990404 @default.
• W3002937224 cites W2905667956 @default.
• W3002937224 cites W4233954896 @default.
• W3002937224 doi "https://doi.org/10.1016/s2214-109x(19)30534-0" @default.
• W3002937224 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31981557" @default.
• W3002937224 hasPublicationYear "2020" @default.
• W3002937224 type Work @default.
• W3002937224 sameAs 3002937224 @default.
• W3002937224 citedByCount "56" @default.
• W3002937224 countsByYear W30029372242020 @default.
• W3002937224 countsByYear W30029372242021 @default.
• W3002937224 countsByYear W30029372242022 @default.
• W3002937224 countsByYear W30029372242023 @default.
• W3002937224 crossrefType "journal-article" @default.
• W3002937224 hasAuthorship W3002937224A5012893141 @default.
• W3002937224 hasAuthorship W3002937224A5019417569 @default.
• W3002937224 hasAuthorship W3002937224A5020754367 @default.
• W3002937224 hasAuthorship W3002937224A5025427376 @default.
• W3002937224 hasAuthorship W3002937224A5032216924 @default.
• W3002937224 hasAuthorship W3002937224A5044132777 @default.
• W3002937224 hasAuthorship W3002937224A5045907837 @default.
• W3002937224 hasAuthorship W3002937224A5047394439 @default.
• W3002937224 hasAuthorship W3002937224A5048283582 @default.
• W3002937224 hasAuthorship W3002937224A5049400743 @default.
• W3002937224 hasAuthorship W3002937224A5051590038 @default.
• W3002937224 hasAuthorship W3002937224A5051728760 @default.
• W3002937224 hasAuthorship W3002937224A5055483615 @default.
• W3002937224 hasAuthorship W3002937224A5090243534 @default.
• W3002937224 hasAuthorship W3002937224A5091815735 @default.
• W3002937224 hasBestOaLocation W30029372241 @default.
• W3002937224 hasConcept C126322002 @default.
• W3002937224 hasConcept C159110408 @default.
• W3002937224 hasConcept C164866538 @default.
• W3002937224 hasConcept C168563851 @default.
• W3002937224 hasConcept C176400912 @default.
• W3002937224 hasConcept C1862650 @default.
• W3002937224 hasConcept C199360897 @default.
• W3002937224 hasConcept C2780665704 @default.
• W3002937224 hasConcept C3013748606 @default.
• W3002937224 hasConcept C3020110884 @default.
• W3002937224 hasConcept C41008148 @default.
• W3002937224 hasConcept C512399662 @default.
• W3002937224 hasConcept C535046627 @default.
• W3002937224 hasConcept C71924100 @default.
• W3002937224 hasConceptScore W3002937224C126322002 @default.
• W3002937224 hasConceptScore W3002937224C159110408 @default.
• W3002937224 hasConceptScore W3002937224C164866538 @default.
• W3002937224 hasConceptScore W3002937224C168563851 @default.
• W3002937224 hasConceptScore W3002937224C176400912 @default.
• W3002937224 hasConceptScore W3002937224C1862650 @default.
• W3002937224 hasConceptScore W3002937224C199360897 @default.
• W3002937224 hasConceptScore W3002937224C2780665704 @default.
• W3002937224 hasConceptScore W3002937224C3013748606 @default.
• W3002937224 hasConceptScore W3002937224C3020110884 @default.
• W3002937224 hasConceptScore W3002937224C41008148 @default.
• W3002937224 hasConceptScore W3002937224C512399662 @default.
• W3002937224 hasConceptScore W3002937224C535046627 @default.
• W3002937224 hasConceptScore W3002937224C71924100 @default.
• W3002937224 hasIssue "2" @default.
• W3002937224 hasLocation W30029372241 @default.
• W3002937224 hasLocation W30029372242 @default.
• W3002937224 hasLocation W30029372243 @default.

• next