Matches in SemOpenAlex for { <https://semopenalex.org/work/W3003295123> ?p ?o ?g. }
- W3003295123 abstract "Abstract Microorganisms that colonize the gastrointestinal tract, collectively known as the gut microbiota, are known to produce small molecules and metabolites that significantly contribute to host intestinal development, functions, and homeostasis. Emerging insights from microbiome research reveal that gut microbiota‐derived signals and molecules influence another key player maintaining intestinal homeostasis—the intestinal stem cell niche, which regulates epithelial self‐renewal. In this review, the literature on gut microbiota‐host crosstalk is surveyed, highlighting the effects of gut microbial metabolites on intestinal stem cells. The production of various classes of metabolites, their actions on intestinal stem cells are discussed and, finally, how the production and function of metabolites are modulated by aging and dietary intake is commented upon." @default.
- W3003295123 created "2020-02-07" @default.
- W3003295123 creator A5062942962 @default.
- W3003295123 creator A5064295225 @default.
- W3003295123 creator A5085452383 @default.
- W3003295123 date "2020-02-24" @default.
- W3003295123 modified "2023-09-30" @default.
- W3003295123 title "Microbial Metabolites and Intestinal Stem Cells Tune Intestinal Homeostasis" @default.
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