Matches in SemOpenAlex for { <https://semopenalex.org/work/W3003320904> ?p ?o ?g. }
- W3003320904 abstract "The simultaneous production of multiple siderophores is considered a general strategy for microorganisms to rapidly adapt to their ever-changing environments. In this study, we show that some Shewanella spp. may downscale their capability for siderophore synthesis to facilitate adaptation. Although S. oneidensis lacks an enzyme specifically synthesizing cadaverine, it can produce it by using promiscuous ornithine decarboxylases. Despite this ability, this bacterium predominately produces the primary siderophore while restraining the production of secondary siderophores by regulating substrate availability. In addition to using the arginine decarboxylase (ADC) pathway for putrescine synthesis, cells optimize the putrescine pool for siderophore production. Our work provides an insight into the coordinated synthesis of multiple siderophores by harnessing promiscuous enzymes in bacteria and underscores the importance of substrate pools for the biosynthesis of natural products." @default.
- W3003320904 created "2020-02-07" @default.
- W3003320904 creator A5023568877 @default.
- W3003320904 creator A5040978227 @default.
- W3003320904 creator A5053979421 @default.
- W3003320904 creator A5068232050 @default.
- W3003320904 creator A5075472480 @default.
- W3003320904 creator A5077345150 @default.
- W3003320904 date "2020-03-18" @default.
- W3003320904 modified "2023-09-25" @default.
- W3003320904 title "Promiscuous Enzymes Cause Biosynthesis of Diverse Siderophores in Shewanella oneidensis" @default.
- W3003320904 cites W1530145064 @default.
- W3003320904 cites W1532422753 @default.
- W3003320904 cites W1954110755 @default.
- W3003320904 cites W1971319907 @default.
- W3003320904 cites W1982263293 @default.
- W3003320904 cites W1988953378 @default.
- W3003320904 cites W1994328828 @default.
- W3003320904 cites W1998936348 @default.
- W3003320904 cites W1999977715 @default.
- W3003320904 cites W2001236306 @default.
- W3003320904 cites W2004026118 @default.
- W3003320904 cites W2005597552 @default.
- W3003320904 cites W2008386225 @default.
- W3003320904 cites W2013740990 @default.
- W3003320904 cites W2014274977 @default.
- W3003320904 cites W2019231363 @default.
- W3003320904 cites W2024610718 @default.
- W3003320904 cites W2029622458 @default.
- W3003320904 cites W2035318758 @default.
- W3003320904 cites W2035816996 @default.
- W3003320904 cites W2040681684 @default.
- W3003320904 cites W2045473823 @default.
- W3003320904 cites W2049514616 @default.
- W3003320904 cites W2059301909 @default.
- W3003320904 cites W2076093949 @default.
- W3003320904 cites W2091251092 @default.
- W3003320904 cites W2099143902 @default.
- W3003320904 cites W2106023343 @default.
- W3003320904 cites W2124513776 @default.
- W3003320904 cites W2139295216 @default.
- W3003320904 cites W2141305696 @default.
- W3003320904 cites W2149552293 @default.
- W3003320904 cites W2152404025 @default.
- W3003320904 cites W2156328657 @default.
- W3003320904 cites W2158483402 @default.
- W3003320904 cites W2170887794 @default.
- W3003320904 cites W2234739035 @default.
- W3003320904 cites W2331266149 @default.
- W3003320904 cites W2495340990 @default.
- W3003320904 cites W2502106085 @default.
- W3003320904 cites W2515194758 @default.
- W3003320904 cites W2515202955 @default.
- W3003320904 cites W2516932902 @default.
- W3003320904 cites W2548630962 @default.
- W3003320904 cites W2550270400 @default.
- W3003320904 cites W2559588208 @default.
- W3003320904 cites W2606664302 @default.
- W3003320904 cites W2755770596 @default.
- W3003320904 cites W2783647467 @default.
- W3003320904 cites W2787022174 @default.
- W3003320904 cites W2789940031 @default.
- W3003320904 cites W2790782665 @default.
- W3003320904 cites W2797167677 @default.
- W3003320904 cites W2799524357 @default.
- W3003320904 cites W2809913031 @default.
- W3003320904 cites W2844719377 @default.
- W3003320904 cites W2887310099 @default.
- W3003320904 cites W2893506532 @default.
- W3003320904 cites W2897308387 @default.
- W3003320904 cites W2971101853 @default.
- W3003320904 doi "https://doi.org/10.1128/aem.00030-20" @default.
- W3003320904 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7082563" @default.
- W3003320904 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32005730" @default.
- W3003320904 hasPublicationYear "2020" @default.
- W3003320904 type Work @default.
- W3003320904 sameAs 3003320904 @default.
- W3003320904 citedByCount "9" @default.
- W3003320904 countsByYear W30033209042021 @default.
- W3003320904 countsByYear W30033209042022 @default.
- W3003320904 countsByYear W30033209042023 @default.
- W3003320904 crossrefType "journal-article" @default.
- W3003320904 hasAuthorship W3003320904A5023568877 @default.
- W3003320904 hasAuthorship W3003320904A5040978227 @default.
- W3003320904 hasAuthorship W3003320904A5053979421 @default.
- W3003320904 hasAuthorship W3003320904A5068232050 @default.
- W3003320904 hasAuthorship W3003320904A5075472480 @default.
- W3003320904 hasAuthorship W3003320904A5077345150 @default.
- W3003320904 hasBestOaLocation W30033209042 @default.
- W3003320904 hasConcept C104317684 @default.
- W3003320904 hasConcept C108319773 @default.
- W3003320904 hasConcept C121289238 @default.
- W3003320904 hasConcept C181199279 @default.
- W3003320904 hasConcept C2776928777 @default.
- W3003320904 hasConcept C2777167505 @default.
- W3003320904 hasConcept C2778824058 @default.
- W3003320904 hasConcept C2781170380 @default.
- W3003320904 hasConcept C2781448169 @default.
- W3003320904 hasConcept C523546767 @default.
- W3003320904 hasConcept C54355233 @default.