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• W3003399279 abstract "Abstract The assessment of platelet spreading through light microscopy, and the subsequent quantification of parameters such as surface area and circularity, is a key assay for many platelet biologists. Here we present an analysis workflow which robustly segments individual platelets to facilitate the analysis of large numbers of cells while minimising user bias. Image segmentation is performed by interactive learning and touching platelets are separated with an efficient semi-automated protocol. We also use machine learning methods to robustly automate the classification of platelets into different subtypes. These adaptable and reproducible workflows are made freely available and are implemented using the open source software KNIME and ilastik." @default.
• W3003399279 created "2020-02-07" @default.
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• W3003399279 date "2020-01-31" @default.
• W3003399279 modified "2023-10-18" @default.
• W3003399279 title "An adaptable analysis workflow for characterization of platelet spreading and morphology" @default.
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• W3003399279 doi "https://doi.org/10.1101/2020.01.31.928168" @default.
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