Matches in SemOpenAlex for { <https://semopenalex.org/work/W3003500078> ?p ?o ?g. }
- W3003500078 endingPage "490" @default.
- W3003500078 startingPage "477" @default.
- W3003500078 abstract "Introduction: Since postmenopausal osteoporosis is a chronic, potentially disabling condition requiring long-term treatment, the physician is expected to decide the optimal treatment strategy, e.g. how to use the available osteoanabolic and antiresorptive agents, sequentially or in combination, in the most effective and safe way, based on personalized patient care.Areas covered: Herein, the authors outline clinical data regarding the efficacy and safety of various sequential treatment strategies. More specifically, they compare the efficacy of osteoanabolic agents when they precede or follow antiresorptive treatment, as well as the efficacy of antiresorptives following other antiresorptives. Finally, the authors quote and discuss available evidence regarding the efficacy and safety of the co-administration of osteoanabolics and antiresorptives in comparison with monotherapies.Expert opinion: Initiation with an osteoanabolic agent followed by an antiresorptive seems to be the optimal treatment sequence, at least in patients with severe osteoporosis. Osteoanabolic treatment following antiresorptives seems to lead in more modest responses in bone mineral density (BMD) and bone turnover markers. Combination therapy with teriparatide and denosumab or zoledronate has achieved higher BMD gains compared to each agent alone; however, due to the high cost, combination therapy is rarely compensated. On the contrary, the combination of teriparatide with alendronate results in smaller BMD increases than TPTD monotherapy." @default.
- W3003500078 created "2020-02-07" @default.
- W3003500078 creator A5027646905 @default.
- W3003500078 creator A5039430897 @default.
- W3003500078 creator A5045916850 @default.
- W3003500078 creator A5081592896 @default.
- W3003500078 date "2020-01-28" @default.
- W3003500078 modified "2023-10-09" @default.
- W3003500078 title "Combination and sequential treatment in women with postmenopausal osteoporosis" @default.
- W3003500078 cites W1559337502 @default.
- W3003500078 cites W1777836280 @default.
- W3003500078 cites W1911703092 @default.
- W3003500078 cites W1965416144 @default.
- W3003500078 cites W1966953695 @default.
- W3003500078 cites W1978319195 @default.
- W3003500078 cites W1981602322 @default.
- W3003500078 cites W1986913997 @default.
- W3003500078 cites W1988801456 @default.
- W3003500078 cites W1989880575 @default.
- W3003500078 cites W1993198539 @default.
- W3003500078 cites W1998642915 @default.
- W3003500078 cites W2001987600 @default.
- W3003500078 cites W2009243945 @default.
- W3003500078 cites W2015350578 @default.
- W3003500078 cites W2021052117 @default.
- W3003500078 cites W2021748249 @default.
- W3003500078 cites W2026949154 @default.
- W3003500078 cites W2028200045 @default.
- W3003500078 cites W2041578222 @default.
- W3003500078 cites W2043210110 @default.
- W3003500078 cites W2057217671 @default.
- W3003500078 cites W2073790420 @default.
- W3003500078 cites W2073804256 @default.
- W3003500078 cites W2080818296 @default.
- W3003500078 cites W2080881316 @default.
- W3003500078 cites W2082134981 @default.
- W3003500078 cites W2090969611 @default.
- W3003500078 cites W2093809946 @default.
- W3003500078 cites W2096179187 @default.
- W3003500078 cites W2096303371 @default.
- W3003500078 cites W2102177673 @default.
- W3003500078 cites W2102587806 @default.
- W3003500078 cites W2103502150 @default.
- W3003500078 cites W2107820403 @default.
- W3003500078 cites W2108106130 @default.
- W3003500078 cites W2108258946 @default.
- W3003500078 cites W2113162921 @default.
- W3003500078 cites W2116817852 @default.
- W3003500078 cites W2118914286 @default.
- W3003500078 cites W2121088079 @default.
- W3003500078 cites W2121418186 @default.
- W3003500078 cites W2127985847 @default.
- W3003500078 cites W2135203315 @default.
- W3003500078 cites W2138829214 @default.
- W3003500078 cites W2139039046 @default.
- W3003500078 cites W2139507272 @default.
- W3003500078 cites W2142900141 @default.
- W3003500078 cites W2145733834 @default.
- W3003500078 cites W2147431786 @default.
- W3003500078 cites W2150904792 @default.
- W3003500078 cites W2150978394 @default.
- W3003500078 cites W2152017463 @default.
- W3003500078 cites W2152063648 @default.
- W3003500078 cites W2169251377 @default.
- W3003500078 cites W2258162599 @default.
- W3003500078 cites W2335178464 @default.
- W3003500078 cites W2414767221 @default.
- W3003500078 cites W2516614130 @default.
- W3003500078 cites W2523651260 @default.
- W3003500078 cites W2583623004 @default.
- W3003500078 cites W2592154370 @default.
- W3003500078 cites W2612475646 @default.
- W3003500078 cites W2621525643 @default.
- W3003500078 cites W2624963411 @default.
- W3003500078 cites W2738136796 @default.
- W3003500078 cites W2743295977 @default.
- W3003500078 cites W2754720807 @default.
- W3003500078 cites W2776086114 @default.
- W3003500078 cites W2793425232 @default.
- W3003500078 cites W2802186890 @default.
- W3003500078 cites W2802834903 @default.
- W3003500078 cites W2803459905 @default.
- W3003500078 cites W2902921438 @default.
- W3003500078 cites W2954020197 @default.
- W3003500078 cites W2968567249 @default.
- W3003500078 cites W2969420040 @default.
- W3003500078 cites W2969940759 @default.
- W3003500078 cites W2982598109 @default.
- W3003500078 cites W2985892442 @default.
- W3003500078 doi "https://doi.org/10.1080/14656566.2020.1717468" @default.
- W3003500078 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31990595" @default.
- W3003500078 hasPublicationYear "2020" @default.
- W3003500078 type Work @default.
- W3003500078 sameAs 3003500078 @default.
- W3003500078 citedByCount "28" @default.
- W3003500078 countsByYear W30035000782020 @default.
- W3003500078 countsByYear W30035000782021 @default.
- W3003500078 countsByYear W30035000782022 @default.