FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3003807790> ?p ?o ?g. }

• W3003807790 endingPage "115561" @default.
• W3003807790 startingPage "115561" @default.
• W3003807790 abstract "Glucocorticoids (GCs) are one of the most prescribed pharmaceutical classes worldwide. They have reached the focus as environmental pollutants in the current scientific research, due to their potential risks to aquatic organisms even in the lower ng L-1 range. The objective of this study was to determine the kinetic behavior of selected GCs and to identify their main transformation products (TPs) in lab scaled biodegradation experiments. Therefore, we analyzed the removal of 13 GCs in aerated incubation experiments with activated sludge taken from a German municipal wastewater treatment plant (WWTP) as inoculum. For all steroids, an exponential decrease of the concentrations was observed, which was modelled by pseudo-first order kinetics. Overall, the rate constants kbiol. ranged from 0.07 L gss-1 d-1 (triamcinolone acetonide) to 250 L gss-1 d-1 (prednisolone). These results emphasize the broad variation in the biodegradability and recalcitrance of certain GCs. The selection of the studied GCs enabled a deduction of microbiological stability related to functional groups. Based on the identified TPs, a variety of enzymatically mediated reactions were postulated. Moreover, the identified TPs are characterized by an intact steroid core structure. Thus residual endocrine activity cannot be ruled out. The main observed reactions were regioselective hydrogenation of carbon double-bonds, degradation of the steroid C17 side-chain, ester hydrolysis and oxidative hydroxylation. In total, 41 TPs were tentatively identified and 22 of them were unambiguously confirmed via reference standards. Additionally, 12 TPs were detected in the effluents of municipal WWTPs and, to the best of our knowledge, the occurrence of eight of these TPs has been shown for the first time. These TPs might significantly contribute to the detected residual endocrine activities in the aquatic environments. Therefore, there is a strong need for efficient removal strategies, in particular for persistent steroid hormones with elevated potencies." @default.
• W3003807790 created "2020-02-07" @default.
• W3003807790 creator A5023217383 @default.
• W3003807790 creator A5029170230 @default.
• W3003807790 creator A5036774257 @default.
• W3003807790 creator A5078218462 @default.
• W3003807790 creator A5083709162 @default.
• W3003807790 date "2020-05-01" @default.
• W3003807790 modified "2023-10-01" @default.
• W3003807790 title "Analysis of the aerobic biodegradation of glucocorticoids: Elucidation of the kinetics and transformation reactions" @default.
• W3003807790 cites W1575441417 @default.
• W3003807790 cites W1792368315 @default.
• W3003807790 cites W1964010911 @default.
• W3003807790 cites W1968118812 @default.
• W3003807790 cites W1972323894 @default.
• W3003807790 cites W1989552101 @default.
• W3003807790 cites W1992667070 @default.
• W3003807790 cites W1993021570 @default.
• W3003807790 cites W1997277260 @default.
• W3003807790 cites W2005135645 @default.
• W3003807790 cites W2006156876 @default.
• W3003807790 cites W2008212693 @default.
• W3003807790 cites W2024033014 @default.
• W3003807790 cites W2034055967 @default.
• W3003807790 cites W2040172532 @default.
• W3003807790 cites W2052806182 @default.
• W3003807790 cites W2053027632 @default.
• W3003807790 cites W2053553993 @default.
• W3003807790 cites W2063516156 @default.
• W3003807790 cites W2078025797 @default.
• W3003807790 cites W2085297848 @default.
• W3003807790 cites W2141052359 @default.
• W3003807790 cites W2148966993 @default.
• W3003807790 cites W2285823523 @default.
• W3003807790 cites W2312413866 @default.
• W3003807790 cites W2327251869 @default.
• W3003807790 cites W2333787293 @default.
• W3003807790 cites W2344032069 @default.
• W3003807790 cites W237851405 @default.
• W3003807790 cites W2400271924 @default.
• W3003807790 cites W2513109887 @default.
• W3003807790 cites W2774660925 @default.
• W3003807790 cites W2790911188 @default.
• W3003807790 cites W2795215758 @default.
• W3003807790 cites W2798021981 @default.
• W3003807790 cites W2801011005 @default.
• W3003807790 cites W2809554803 @default.
• W3003807790 cites W2810674123 @default.
• W3003807790 cites W2902482662 @default.
• W3003807790 cites W2925752324 @default.
• W3003807790 cites W2954129030 @default.
• W3003807790 cites W297083069 @default.
• W3003807790 cites W4229814691 @default.
• W3003807790 doi "https://doi.org/10.1016/j.watres.2020.115561" @default.
• W3003807790 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32087415" @default.
• W3003807790 hasPublicationYear "2020" @default.
• W3003807790 type Work @default.
• W3003807790 sameAs 3003807790 @default.
• W3003807790 citedByCount "19" @default.
• W3003807790 countsByYear W30038077902020 @default.
• W3003807790 countsByYear W30038077902021 @default.
• W3003807790 countsByYear W30038077902022 @default.
• W3003807790 countsByYear W30038077902023 @default.
• W3003807790 crossrefType "journal-article" @default.
• W3003807790 hasAuthorship W3003807790A5023217383 @default.
• W3003807790 hasAuthorship W3003807790A5029170230 @default.
• W3003807790 hasAuthorship W3003807790A5036774257 @default.
• W3003807790 hasAuthorship W3003807790A5078218462 @default.
• W3003807790 hasAuthorship W3003807790A5083709162 @default.
• W3003807790 hasConcept C107872376 @default.
• W3003807790 hasConcept C147455438 @default.
• W3003807790 hasConcept C157021035 @default.
• W3003807790 hasConcept C178790620 @default.
• W3003807790 hasConcept C181199279 @default.
• W3003807790 hasConcept C185592680 @default.
• W3003807790 hasConcept C2780902042 @default.
• W3003807790 hasConcept C2781109383 @default.
• W3003807790 hasConcept C39432304 @default.
• W3003807790 hasConcept C43617362 @default.
• W3003807790 hasConcept C55493867 @default.
• W3003807790 hasConcept C71315377 @default.
• W3003807790 hasConcept C87717796 @default.
• W3003807790 hasConcept C94061648 @default.
• W3003807790 hasConcept C94412978 @default.
• W3003807790 hasConceptScore W3003807790C107872376 @default.
• W3003807790 hasConceptScore W3003807790C147455438 @default.
• W3003807790 hasConceptScore W3003807790C157021035 @default.
• W3003807790 hasConceptScore W3003807790C178790620 @default.
• W3003807790 hasConceptScore W3003807790C181199279 @default.
• W3003807790 hasConceptScore W3003807790C185592680 @default.
• W3003807790 hasConceptScore W3003807790C2780902042 @default.
• W3003807790 hasConceptScore W3003807790C2781109383 @default.
• W3003807790 hasConceptScore W3003807790C39432304 @default.
• W3003807790 hasConceptScore W3003807790C43617362 @default.
• W3003807790 hasConceptScore W3003807790C55493867 @default.
• W3003807790 hasConceptScore W3003807790C71315377 @default.
• W3003807790 hasConceptScore W3003807790C87717796 @default.
• W3003807790 hasConceptScore W3003807790C94061648 @default.

• next