Matches in SemOpenAlex for { <https://semopenalex.org/work/W3004575129> ?p ?o ?g. }
Showing items 1 to 81 of
81
with 100 items per page.
- W3004575129 abstract "Polycyclic polyprenylated acylphloroglucinols (PPAPs) exhibit a broad range of biological activities, such asantidepressant, antibacterial, antiviral and antitumor properties. The content of PPAPs in the producing plants is oftenquite low, and their complex structures make total chemical synthesis difficult and economically impractical. Progressesin synthetic biology provide an alternative approach for the production of these valuable compounds. Here we presentour results on reconstruction of the biosynthetic pathways of PPAP precursors in yeast. Based on our previous works onthe biosynthesis of PPAPs, genes involved in the formation of benzophenones and xanthones from Hypericum sp. andother organisms were expressed in yeast either episomally or by integration into the genome. The production of theexpected products reached around 0.5 mg/l, which is high enough to be the substrate for enzymes of subsequentbiosynthetic steps. The yeast strains will be further engineered by introducing various prenyltransferase enzymes toreconstruct the full biosynthetic pathways of PPAPs." @default.
- W3004575129 created "2020-02-14" @default.
- W3004575129 creator A5023946440 @default.
- W3004575129 creator A5035982169 @default.
- W3004575129 creator A5043435997 @default.
- W3004575129 creator A5052164619 @default.
- W3004575129 creator A5076132183 @default.
- W3004575129 creator A5077269194 @default.
- W3004575129 date "2020-01-01" @default.
- W3004575129 modified "2023-09-26" @default.
- W3004575129 title "Engineering Yeast for Production of Benzophenones and Xanthones as Precursors of Polycyclic Polyprenylated Acylphloroglucinols" @default.
- W3004575129 hasPublicationYear "2020" @default.
- W3004575129 type Work @default.
- W3004575129 sameAs 3004575129 @default.
- W3004575129 citedByCount "0" @default.
- W3004575129 crossrefType "journal-article" @default.
- W3004575129 hasAuthorship W3004575129A5023946440 @default.
- W3004575129 hasAuthorship W3004575129A5035982169 @default.
- W3004575129 hasAuthorship W3004575129A5043435997 @default.
- W3004575129 hasAuthorship W3004575129A5052164619 @default.
- W3004575129 hasAuthorship W3004575129A5076132183 @default.
- W3004575129 hasAuthorship W3004575129A5077269194 @default.
- W3004575129 hasConcept C161790260 @default.
- W3004575129 hasConcept C178790620 @default.
- W3004575129 hasConcept C181199279 @default.
- W3004575129 hasConcept C185592680 @default.
- W3004575129 hasConcept C191503008 @default.
- W3004575129 hasConcept C191908910 @default.
- W3004575129 hasConcept C2776085463 @default.
- W3004575129 hasConcept C2778626014 @default.
- W3004575129 hasConcept C2779222958 @default.
- W3004575129 hasConcept C553450214 @default.
- W3004575129 hasConcept C55493867 @default.
- W3004575129 hasConcept C6350086 @default.
- W3004575129 hasConcept C65024703 @default.
- W3004575129 hasConcept C70721500 @default.
- W3004575129 hasConcept C71240020 @default.
- W3004575129 hasConcept C86803240 @default.
- W3004575129 hasConceptScore W3004575129C161790260 @default.
- W3004575129 hasConceptScore W3004575129C178790620 @default.
- W3004575129 hasConceptScore W3004575129C181199279 @default.
- W3004575129 hasConceptScore W3004575129C185592680 @default.
- W3004575129 hasConceptScore W3004575129C191503008 @default.
- W3004575129 hasConceptScore W3004575129C191908910 @default.
- W3004575129 hasConceptScore W3004575129C2776085463 @default.
- W3004575129 hasConceptScore W3004575129C2778626014 @default.
- W3004575129 hasConceptScore W3004575129C2779222958 @default.
- W3004575129 hasConceptScore W3004575129C553450214 @default.
- W3004575129 hasConceptScore W3004575129C55493867 @default.
- W3004575129 hasConceptScore W3004575129C6350086 @default.
- W3004575129 hasConceptScore W3004575129C65024703 @default.
- W3004575129 hasConceptScore W3004575129C70721500 @default.
- W3004575129 hasConceptScore W3004575129C71240020 @default.
- W3004575129 hasConceptScore W3004575129C86803240 @default.
- W3004575129 hasLocation W30045751291 @default.
- W3004575129 hasOpenAccess W3004575129 @default.
- W3004575129 hasPrimaryLocation W30045751291 @default.
- W3004575129 hasRelatedWork W1994525974 @default.
- W3004575129 hasRelatedWork W2077378005 @default.
- W3004575129 hasRelatedWork W2143322189 @default.
- W3004575129 hasRelatedWork W2288341653 @default.
- W3004575129 hasRelatedWork W2463328062 @default.
- W3004575129 hasRelatedWork W2512713630 @default.
- W3004575129 hasRelatedWork W2613680770 @default.
- W3004575129 hasRelatedWork W2696099391 @default.
- W3004575129 hasRelatedWork W2771313443 @default.
- W3004575129 hasRelatedWork W2805635045 @default.
- W3004575129 hasRelatedWork W2944669622 @default.
- W3004575129 hasRelatedWork W2967765437 @default.
- W3004575129 hasRelatedWork W2980418682 @default.
- W3004575129 hasRelatedWork W2990651486 @default.
- W3004575129 hasRelatedWork W3014474848 @default.
- W3004575129 hasRelatedWork W3014695728 @default.
- W3004575129 hasRelatedWork W3047906548 @default.
- W3004575129 hasRelatedWork W3062354935 @default.
- W3004575129 hasRelatedWork W3180841516 @default.
- W3004575129 hasRelatedWork W3197491374 @default.
- W3004575129 isParatext "false" @default.
- W3004575129 isRetracted "false" @default.
- W3004575129 magId "3004575129" @default.
- W3004575129 workType "article" @default.