FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3004708987> ?p ?o ?g. }

• W3004708987 endingPage "54" @default.
• W3004708987 startingPage "45" @default.
• W3004708987 abstract "Aim: The present research work discussed the preparation of lomustine loaded with chitosan nanoparticles (LNCp) by ionic gelation method with homogenization using the design on experiments by Box-Behnken design. Methods: The nanoparticles are evaluated by particle size, zeta potential, surface morphology, drug content, entrapment efficiency and in-vitro drug release. Results: The FT-IR results support that drug have no interaction with excipients, which are used in the preparation of nanoparticle. The particle size, drug content and encapsulation efficiency of the developed nanoparticles ranged from 190 to 255 nm, 80.88% to 94.02%, and 77.12 to 88.74%, respectively. The drug release rate is diffusion-controlled over 8 hours. The F-value for all of the responses shows that the models are significant. The p-value, less than 0.05 for all the responses reveals the significance of the models. Graphical optimisation is done by desirability plot and overlay plot, which contains optimal values of independent variables with the desirability of 1. Conclusion: In conclusion, the results suggested that the optimised lomustine loaded chitosan nanoparticles are useful for brain targeting hence hold the potential for further research and clinical application." @default.
• W3004708987 created "2020-02-14" @default.
• W3004708987 creator A5016437276 @default.
• W3004708987 creator A5026474821 @default.
• W3004708987 creator A5050038327 @default.
• W3004708987 creator A5086557332 @default.
• W3004708987 creator A5091375645 @default.
• W3004708987 date "2020-08-27" @default.
• W3004708987 modified "2023-09-24" @default.
• W3004708987 title "Design and Development of Lomustine Loaded Chitosan Nanoparticles for Efficient Brain Targeting" @default.
• W3004708987 cites W1783355274 @default.
• W3004708987 cites W1861040943 @default.
• W3004708987 cites W1963866419 @default.
• W3004708987 cites W1987344321 @default.
• W3004708987 cites W2023803166 @default.
• W3004708987 cites W2024268060 @default.
• W3004708987 cites W2044433401 @default.
• W3004708987 cites W2059528376 @default.
• W3004708987 cites W2093512316 @default.
• W3004708987 cites W2136348158 @default.
• W3004708987 cites W2139140183 @default.
• W3004708987 cites W2152626109 @default.
• W3004708987 cites W2263785669 @default.
• W3004708987 cites W2266732512 @default.
• W3004708987 cites W2266814182 @default.
• W3004708987 cites W2273891682 @default.
• W3004708987 cites W2280449106 @default.
• W3004708987 cites W2401124890 @default.
• W3004708987 cites W2475807018 @default.
• W3004708987 cites W2517732758 @default.
• W3004708987 cites W2619415329 @default.
• W3004708987 cites W2762785181 @default.
• W3004708987 cites W2775520115 @default.
• W3004708987 cites W2778335776 @default.
• W3004708987 cites W2794922400 @default.
• W3004708987 cites W2885181252 @default.
• W3004708987 cites W2889303739 @default.
• W3004708987 cites W2913867518 @default.
• W3004708987 cites W2935358028 @default.
• W3004708987 cites W4239646698 @default.
• W3004708987 doi "https://doi.org/10.2174/1871525718666200203112502" @default.
• W3004708987 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32013840" @default.
• W3004708987 hasPublicationYear "2020" @default.
• W3004708987 type Work @default.
• W3004708987 sameAs 3004708987 @default.
• W3004708987 citedByCount "1" @default.
• W3004708987 countsByYear W30047089872020 @default.
• W3004708987 crossrefType "journal-article" @default.
• W3004708987 hasAuthorship W3004708987A5016437276 @default.
• W3004708987 hasAuthorship W3004708987A5026474821 @default.
• W3004708987 hasAuthorship W3004708987A5050038327 @default.
• W3004708987 hasAuthorship W3004708987A5086557332 @default.
• W3004708987 hasAuthorship W3004708987A5091375645 @default.
• W3004708987 hasConcept C141071460 @default.
• W3004708987 hasConcept C147789679 @default.
• W3004708987 hasConcept C150077022 @default.
• W3004708987 hasConcept C155672457 @default.
• W3004708987 hasConcept C170295934 @default.
• W3004708987 hasConcept C171250308 @default.
• W3004708987 hasConcept C185592680 @default.
• W3004708987 hasConcept C187530423 @default.
• W3004708987 hasConcept C192562407 @default.
• W3004708987 hasConcept C2776694085 @default.
• W3004708987 hasConcept C2776755627 @default.
• W3004708987 hasConcept C2779429289 @default.
• W3004708987 hasConcept C2779434656 @default.
• W3004708987 hasConcept C2779732960 @default.
• W3004708987 hasConcept C2780035454 @default.
• W3004708987 hasConcept C43617362 @default.
• W3004708987 hasConcept C55493867 @default.
• W3004708987 hasConcept C71924100 @default.
• W3004708987 hasConcept C86181022 @default.
• W3004708987 hasConcept C98274493 @default.
• W3004708987 hasConceptScore W3004708987C141071460 @default.
• W3004708987 hasConceptScore W3004708987C147789679 @default.
• W3004708987 hasConceptScore W3004708987C150077022 @default.
• W3004708987 hasConceptScore W3004708987C155672457 @default.
• W3004708987 hasConceptScore W3004708987C170295934 @default.
• W3004708987 hasConceptScore W3004708987C171250308 @default.
• W3004708987 hasConceptScore W3004708987C185592680 @default.
• W3004708987 hasConceptScore W3004708987C187530423 @default.
• W3004708987 hasConceptScore W3004708987C192562407 @default.
• W3004708987 hasConceptScore W3004708987C2776694085 @default.
• W3004708987 hasConceptScore W3004708987C2776755627 @default.
• W3004708987 hasConceptScore W3004708987C2779429289 @default.
• W3004708987 hasConceptScore W3004708987C2779434656 @default.
• W3004708987 hasConceptScore W3004708987C2779732960 @default.
• W3004708987 hasConceptScore W3004708987C2780035454 @default.
• W3004708987 hasConceptScore W3004708987C43617362 @default.
• W3004708987 hasConceptScore W3004708987C55493867 @default.
• W3004708987 hasConceptScore W3004708987C71924100 @default.
• W3004708987 hasConceptScore W3004708987C86181022 @default.
• W3004708987 hasConceptScore W3004708987C98274493 @default.
• W3004708987 hasFunder F4320320716 @default.
• W3004708987 hasIssue "1" @default.
• W3004708987 hasLocation W30047089871 @default.
• W3004708987 hasOpenAccess W3004708987 @default.
• W3004708987 hasPrimaryLocation W30047089871 @default.

• next