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- W3004776766 abstract "Abstract Objective Our objectives were to 1) quantify the frequency of wheezing episodes and asthma diagnosis in young children in a large pediatric primary care network and 2) assess the variability in practice-level asthma diagnosis, accounting for common asthma risk factors and comorbidities. We hypothesized that significant variability in practice-level asthma diagnosis rates would remain after adjusting for associated predictors. Methods We generated a retrospective longitudinal birth cohort of children who visited 1 of 31 pediatric primary care practices within the first 6 months of life from 1/2005 to 12/2016. Children were observed for up to 8 years or until the end of the observation window. We used multivariable discrete time survival models to evaluate predictors of asthma diagnosis by 3-month age intervals. We compared unadjusted and adjusted proportions of children diagnosed with asthma by practice. Results Of the 161,502 children in the cohort, 34,578 children (21%) received at least 1 asthma diagnosis. In multivariable modeling, male gender, minority race/ethnicity, gestational age Conclusions Across pediatric primary care practices, adjusted incidence of asthma diagnosis by age 6 years ranged widely, though variation gauged by the interquartile range was more modest. Potential sources of practice-level variation, such as differing diagnosis thresholds and labeling of different wheezing phenotypes as “asthma,” should be further investigated." @default.
- W3004776766 created "2020-02-14" @default.
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- W3004776766 date "2020-09-01" @default.
- W3004776766 modified "2023-10-18" @default.
- W3004776766 title "Variability in Diagnosed Asthma in Young Children in a Large Pediatric Primary Care Network" @default.
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- W3004776766 doi "https://doi.org/10.1016/j.acap.2020.02.003" @default.
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