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• W3004779294 endingPage "340" @default.
• W3004779294 startingPage "321" @default.
• W3004779294 abstract "Poly(ADP-ribose) polymerases (PARPs or ARTDs), originally described as DNA repair factors, have metabolic regulatory roles. PARP1, PARP2, PARP7, PARP10, and PARP14 regulate central and peripheral carbohydrate and lipid metabolism and often channel pathological disruptive metabolic signals. PARP1 and PARP2 are crucial for adipocyte differentiation, including the commitment toward white, brown, or beige adipose tissue lineages, as well as the regulation of lipid accumulation. Through regulating adipocyte function and organismal energy balance, PARPs play a role in obesity and the consequences of obesity. These findings can be translated into humans, as evidenced by studies on identical twins and SNPs affecting PARP activity." @default.
• W3004779294 created "2020-02-14" @default.
• W3004779294 creator A5010130460 @default.
• W3004779294 creator A5077174799 @default.
• W3004779294 date "2020-02-06" @default.
• W3004779294 modified "2023-10-18" @default.
• W3004779294 title "The role of ADP-ribose metabolism in metabolic regulation, adipose tissue differentiation, and metabolism" @default.
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